Results 61 to 70 of about 1,679,146 (250)

Small Cell Carcinoma of Ovary, Hypercalcemic Type (Malignant Rhabdoid Tumor of Ovary) with Loss of SMARCA4 (BRG1) Expression: Report of Two Cases

Türk Patoloji Dergisi, 2020
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) / malignant rhabdoid tumor of the ovary (MRTO) is a rare tumor affecting young women. It is frequently misdiagnosed due to overlapping morphological and immunohistochemical features with many
Ayushi SAHAY, Katha KANTE, Santosh MENON, Jaya GHOSH, Rajendra A. KERKAR, Kedar K. DEODHAR   +5 more
doaj   +1 more source

Role of immunohistochemistry in gynec oncopathology including specific diagnostic scenarios with associated treatment implications

Indian Journal of Pathology and Microbiology, 2020
Over the years, immunohistochemistry has emerged as a powerful tool for a more precise diagnosis of certain tumors in gynecologic oncopathology and resolving certain diagnostic dilemmas with significant treatment implications.
Bharat Rekhi
doaj   +1 more source

Aspiration cytology of pleomorphic adenoma with squamous metaplasia: A case series and literature review illustrating diagnostic challenges

, 2022
Objective: Squamous metaplasia is not uncommonly observed in salivary gland neoplasms, including pleomorphic adenomas (PAs). It poses as a diagnostic pitfall with cytomorphologic features overlapping with low-grade epithelial malignances and carcinoma ex-
Eric H. L. Lau, Amy B. W. Chan, Joshua J. X. Li, Li, Joshua J.X., Lau, Eric H.L., Joanna K. M. Ng, Chan, Amy B.W., Ng, Joanna K.M.   +7 more
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

TRK immunohistochemistry in pediatric rhabdomyosarcomas: diagnostic and prognostic utility and limitations

Pathology and Oncology Research
Rhabdomyosarcoma is the third most common extracranial solid tumor in childhood. Treatment of patients is multimodal, based on systemic chemotherapy and local therapy by surgery and/or radiotherapy.
Renáta Lajti, Katalin Dezső, Zoltán Sápi, Gergő Papp, Anna Mohás, Bence Bukovszky, Sándor Szabó, Luca Felkai, Monika Csóka   +8 more
doaj   +1 more source

Immunohistochemistry as an Important Tool in Biomarkers Detection and Clinical Practice

, 2010
The immunohistochemistry technique is used in the search for cell or tissue antigens that range from amino acids and proteins to infectious agents and specific cellular populations.
Leandro Luongo de Matos, Maria Aparecida da Silva Pinhal, Damila Cristina Trufelli, Maria Graciela Luongo de Matos   +3 more
core   +1 more source

"Interchangeability" of PD-L1 immunohistochemistry assays:a meta-analysis of diagnostic accuracy [PDF]

, 2020
Different clones, protocol conditions, instruments, and scoring/readout methods may pose challenges in introducing different PD-L1 assays for immunotherapy.
Fujimoto, D., Ratcliffe, M. J., Chung, Jin-Haeng, Xu, Z., Ionescu, Diana, Chan, A. W. H., Okuda, Katsuhiro, Tsao, Ming-Sound, Tretiakova, Maria, Torlakovic, Emina, Vainer, G. W., Soo, Ross A, Fiset, Pierre O, Hirsch, F. R., Han, Gang, Bigras, Gilbert, Ross, C., Scheel, Andreas H, Rimm, D. L., Cheung, C. C., Torlakovic, E., Xu, Zhaolin, Soo, R. A., Munari, E., Ross, Catherine, Ilie, M., Zielinski, Dirk, Tretiakova, M., Cheung, Carol C, Adam, Julien, Fujimoto, Daichi, Couture, Christian, Ratcliffe, Marianne J, Lim, H. J., Vainer, Gilad W, Røge, R., Munari, Enrico, Lim, Hyun J, Barnes, P., Ionescu, D., Wang, H., Swanson, P. E., To, K. F., Barnes, Penny, Li, C., Røge, Rasmus; id_orcid, To, Ka F, Han, G., Fiset, P. O., Zielinski, D., Okuda, K., Wang, Hangjun, Chan, Anthony W H, Bigras, G., Adam, J., Ilie, Marius, Scheel, A. H., Tsao, M. -S., Rimm, David L, Hirsch, Fred R, Chung, J. -H., Li, Chao, Couture, C., Swanson, Paul E   +63 more
core   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

A diagnostic study of bovine endometritis integrating cytological, histopathological assessments, and immunohistochemical localizations of interleukins [PDF]

Iraqi Journal of Veterinary Sciences
Endometritis significantly impairs cows' reproductive productivity, yet existing diagnostic practices lack the comprehensive accuracy required for precise diagnosis and pathological staging. This study aimed to evaluate and validate a combined diagnostic
Wardi M. Hassan, Isam B. Sharum
doaj   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source