Results 81 to 90 of about 1,729,034 (298)

A mixed effect model for bivariate meta-analysis of diagnostic test accuracy studies using a copula representation of the random effects distribution [PDF]

, 2015
Diagnostic test accuracy studies typically report the number of true positives, false positives, true negatives and false negatives. There usually exists a negative association between the number of true positives and true negatives, because studies that
Arends, Aristidis K. Nikoloulopoulos, Brechmann, Chu, Chu, Chu, Chu, Demidenko, Genest, Genest, Genest, Genest, Glas, Hamza, Harbord, Harbord, Heffernan, Hua, Hult, Jackson, Jackson, Joe, Joe, Joe, Joe, Kurowicka, Kuss, Lee, Ma, Mavridis, Mavridis, Nash, Nelsen, Nikoloulopoulos, Nikoloulopoulos, Nikoloulopoulos, Nikoloulopoulos, Nikoloulopoulos, Nikoloulopoulos, Normand, Paul, Reitsma, Riley R, Rutter, Rücker, Sarmanov, Scheidler, Serfling, Shen, Sklar, Stroud, Vuong   +51 more
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Selected microgravity combustion diagnostic techniques [PDF]

During FY 1989-1992, several diagnostic techniques for studying microgravity combustion have moved from the laboratory to use in reduced-gravity facilities.
Greenberg, Paul S., Griffin, Devon W.
core   +1 more source

Automated post-fault diagnosis of power system disturbances [PDF]

, 2006
In order to automate the analysis of SCADA and digital fault recorder (DFR) data for a transmission network operator in the UK, the authors have developed an industrial strength multi-agent system entitled protection engineering diagnostic agents (PEDA).
Davidson, E.M., McArthur, S.D.J.
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Rapid detection of zoonotic Streptococcus suis serotype 2 and 14 by enzyme-activated probe fluorescence quantitative PCR method

BMC Veterinary Research
Streptococcus suis serotypes 2 and 14 are the most common zoonotic strains, but previous identification methods made distinguish these two serotypes from other S. suis serotypes difficult.
Yaxing Su, Jiajia Meng, Mingwei Zhao, Chunling Li, Shaolun Zhai, Yan Li, Pinpin Chu, Zhibiao Bian, Kunli Zhang, Dongxia Yang, Zhiyong Jiang, Hongchao Gou, Chenggang Xu   +12 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Qualitative model-based diagnostics for rocket systems [PDF]

A diagnostic software package is currently being developed at NASA LeRC that utilizes qualitative model-based reasoning techniques. These techniques can provide diagnostic information about the operational condition of the modeled rocket engine system or
Fulton, Christopher, Jankovsky, Amy, Maul, William, Meyer, Claudia   +3 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Explanation-based learning for diagnosis [PDF]

, 1992
Diagnostic expert systems constructed using traditional knowledge-engineering techniques identify malfunctioning components using rules that associate symptoms with diagnoses. Model-based diagnosis (MBD) systems use models of devices to find faults given
Fattah, Yousri El, O'Rorke, Paul
core   +1 more source