Results 101 to 110 of about 1,354,199 (345)

Global burden of human brucellosis : a systematic review of disease frequency [PDF]

, 2012
BACKGROUND: This report presents a systematic review of scientific literature published between 1990-2010 relating to the frequency of human brucellosis, commissioned by WHO.
A El Sherbini, A Yacoub, AA Haghdoost, Anna S. Dean, B Bonfoh, B Hernandez, E Jelastopulu, E Schelling, Esther Schelling, F De Massis, F Roth, FK Al-Ani, G Marder, G Pappas, GJ Jennings, Helena Greter, Hélène Carabin, I Avdikou, J Ariza, J Zinsstag, J Zinsstag, JA Al Tawfiq, JA Crump, Jakob Zinsstag, KE Elbeltagy, Lisa Crump, M Minas, MA Al Sekait, MA Idris, MR Hosseini, MR Khorasgani, N Gargouri, O Karabay, QM Abu Shaqra, R Awad, S Vancelik, SA Dahouk, SM Alavi, SR Alballa, TJ Doyle, Z Cetinkaya   +40 more
core   +4 more sources

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

The development of a machine learning algorithm for early detection of viral hepatitis B infection in Nigerian patients

Scientific Reports, 2023
Access to Hepatitis B Virus (HBV) testing for people in low-resource settings has long been challenging due to the gold standard, enzyme immunoassay, being prohibitively expensive, and requiring specialised skills and facilities that are not readily ...
Busayo I. Ajuwon, Alice Richardson, Katrina Roper, Meru Sheel, Rosemary Audu, Babatunde L. Salako, Matthew O. Bojuwoye, Ibraheem A. Katibi, Brett A. Lidbury   +8 more
doaj   +1 more source

The differential diagnosis of Huntington's disease-like syndromes: 'red flags' for the clinician [PDF]

, 2013
A growing number of progressive heredodegenerative conditions mimic the presentation of Huntington's disease (HD). Differentiating among these HD-like syndromes is necessary when a patient with a combination of movement disorders, cognitive decline ...
Bhatia, KP, Martino, D, Stamelou, M
core  

MISSED: an environment for mixed-signal microsystem testing and diagnosis [PDF]

, 1993
A tight link between design and test data is proposed for speeding up test-pattern generation and diagnosis during mixed-signal prototype verification. Test requirements are already incorporated at the behavioral level and specified with increased detail
Docherty, G., Kerkhoff, H.G.
core   +3 more sources

Prospective Evaluation of Three Rapid Diagnostic Tests for Diagnosis of Human Leptospirosis

PLoS Neglected Tropical Diseases, 2013
Background Diagnosis of leptospirosis by the microscopic agglutination test (MAT) or by culture is confined to specialized laboratories. Although ELISA techniques are more common, they still require laboratory facilities.
M. Goris, M. Leeflang, M. Lodén, J. Wagenaar, P. Klatser, R. Hartskeerl, K. Boer   +6 more
semanticscholar   +1 more source

Routine use of coronary computed tomography as initial diagnostic test for angina pectoris

Archives of Cardiovascular Diseases, 2011
Coronary computed tomography (CCT) detects coronary obstruction with high sensitivity and might be useful for diagnosis of angina pectoris.In this pilot study, we sought to prospectively evaluate the performance of CCT as initial work up and determine the significance of this strategy according to the pretest likelihood of having coronary artery ...
Edouard Cheneau, Annamaria Molon, Laurent Bernard, Dimitri Panagides, Bruno Vahdat   +4 more
openaire   +3 more sources

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Comparison of Ultrasonography and Radiography in Detection of Thoracic Bone Fractures; a Systematic Review and Meta-Analysis

Emergency, 2016
Introduction: The potential benefit of ultrasonography for detection of thoracic bone fractures has been proven in various surveys but no comprehensive conclusion has been drawn yet; therefore, the present study aimed to conduct a thorough meta-analytic ...
Mahmoud Yousefifard, Masoud Baikpour, Parisa Ghelichkhani, Hadi Asady, Abolfazl Darafarin, Mohammad Reza Amini Esfahani, Mostafa Hosseini, Mehdi Yaseri, Saeed Safari   +8 more
doaj  

Non-invasive testing for early detection of neovascular macular degeneration in unaffected second eyes of older adults: EDNA diagnostic accuracy study

Health Technology Assessment, 2022
Background: Neovascular age-related macular degeneration is a leading cause of sight loss, and early detection and treatment is important. For patients with neovascular age-related macular degeneration in one eye, it is usual practice to monitor the ...
Katie Banister, Jonathan A Cook, Graham Scotland, Augusto Azuara-Blanco, Beatriz Goulão, Heinrich Heimann, Rodolfo Hernández, Ruth Hogg, Charlotte Kennedy, Sobha Sivaprasad, Craig Ramsay, Usha Chakravarthy   +11 more
doaj   +1 more source