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Solid and liquid phase Raman and infrared spectra of diallyl sulfide and diallyl disulfide
Journal of Molecular Structure, 1989Abstract The Raman and IR spectra of diallyl sulfide and diallyl disulfide in the liquid and solid state are reported and examined in order to determine their most stable conformations. In both the liquid and solid state, the allyl moieties in both molecules are in a “gauche” conformation in which the sulfur atoms and the terminal vinyl carbons ...
Mark T. Devlin +2 more
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Synthesis, characterization and bioactivity evaluation of diallyl disulfide
Journal of Central South University of Technology, 2006Diallyl disulfide was synthesized by phase transfer catalyst (PTC) during microwave irradiation. The effects of different factors, such as the power of microwave irradiation, the time of microwave irradiation, PTC reagents amount and the mole ratio of reactants, on the yield of product were investigated.
Xin-ke Yuan +3 more
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Journal of Toxicology and Environmental Health, 1995
The chemopreventive properties of allyl sulfides on carcinogenesis may be related to the modulation of drug-metabolizing enzymes involved in carcinogen activation or detoxication. In order to investigate the effects of diallyl sulfide (DAS) and diallyl disulfide (DADS) on intestinal and hepatic drug-metabolizing enzymes, rats were fed a diet containing
Haber, Delphine +4 more
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The chemopreventive properties of allyl sulfides on carcinogenesis may be related to the modulation of drug-metabolizing enzymes involved in carcinogen activation or detoxication. In order to investigate the effects of diallyl sulfide (DAS) and diallyl disulfide (DADS) on intestinal and hepatic drug-metabolizing enzymes, rats were fed a diet containing
Haber, Delphine +4 more
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Diallyl disulfide impairs hippocampal neurogenesis in the young adult brain
Toxicology Letters, 2013Garlic and garlic extracts are used as seasonings and are generally considered beneficial to human health, which include antioxidant and neuroprotective properties in neurological disorders. In the present study, we examined the effects of garlic sulfur components on the proliferation of neural progenitor cells (NPCs) and hippocampal neurogenesis.
Seung Taek, Ji +7 more
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Diallyl disulfide in oncotherapy: molecular mechanisms and therapeutic potentials
ApoptosisGarlic possesses a broad spectrum of medicinal properties, such as anti-cancer, antioxidant, anti-diabetic effects, and protective effects on the heart, nervous system, and liver. Diallyl disulfide (DADS), an oil-soluble organic sulfur-containing compound in garlic, has garnered attention in recent years for its demonstrated anti-cancer efficacy in ...
Yun-Fei, Zhou +5 more
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Differentiating and growth inhibitory effects of diallyl disulfide on cancer cells
International Journal of Oncology, 1997Diallyl disulfide caused growth inhibition and differentiation of DS19 mouse erythroleukemic cells as judged by hemoglobin synthesis and induction of acetylcholinesterase activity. There was a 50% inhibition of cell division at about 0.25 mM diallyl disulfide which was much more effective than diallyl sulfide. K562 human erythroleukemia cells and mouse
M, Lea, U, Ayyala
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Russian Journal of Electrochemistry, 2018
The study of the binding of heavy metal ions by organosulfur compounds of garlic is especially important for the understanding of many biological systems. Cadmium is a non-essential heavy metal known to be one of the most toxic environmental pollutant.Interactions between cadmium and diallyl disulfide (DADS), dimethyl disulfide (DMDS) and diallyl ...
Mohammad Ali Kamyabi +2 more
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The study of the binding of heavy metal ions by organosulfur compounds of garlic is especially important for the understanding of many biological systems. Cadmium is a non-essential heavy metal known to be one of the most toxic environmental pollutant.Interactions between cadmium and diallyl disulfide (DADS), dimethyl disulfide (DMDS) and diallyl ...
Mohammad Ali Kamyabi +2 more
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Anti-Cancer Drugs, 1996
The effects of diallyl sulfide (DAS) and diallyl disulfide (DADS) on cisplatin-induced changes in glutathione (GSH) and glutathione-S-transferase (GST) activity in rat liver and kidney was investigated. Cisplatin treatment significantly (p < 0.05) decreased GSH and GST activity in both liver and kidney.
C, Dwivedi, A, Abu-Ghazaleh, J, Guenther
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The effects of diallyl sulfide (DAS) and diallyl disulfide (DADS) on cisplatin-induced changes in glutathione (GSH) and glutathione-S-transferase (GST) activity in rat liver and kidney was investigated. Cisplatin treatment significantly (p < 0.05) decreased GSH and GST activity in both liver and kidney.
C, Dwivedi, A, Abu-Ghazaleh, J, Guenther
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Effect of diallyl disulfide on the hepatic glutathione reductase activity
Archives of Pharmacal Research, 1988The effect of diallyl disulfide on the cytosolic glutathione reductase activity in mouse liver was studied. After treatment with diallyl disulfide, hepatic cytosolic glutathione reductase activity was increased with dose-dependent pattern as compared to control. The Vmax of glutathione reductase was increased by the treatment of diallyl disulfide.
Keun Huh, Jong-Min Park, Sang-Il Lee
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Effect of Diallyl Disulfide Immobilization on the Immunoreaction of Polysulfone Membranes
Textile Research Journal, 2009Diallyl disulfide (DADS) was covalently bonded to a layer of poly(acrylic acid) grafting on the surface of polysulfone (PSF) membranes. The effects of DADS bonding on oxidative stress, removal of cholesterol, triglyceride and endotoxin, and the ability of thrombus prevention were then evaluated.
Chang, L.S. +3 more
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