Diallyl Trisulfide, the Antifungal Component of Garlic Essential Oil and the Bioactivity of Its Nanoemulsions Formed by Spontaneous Emulsification [PDF]
Molecules, 2021 The aim of this study was to evaluate the chemical compounds of garlic essential oil (EO), and determine the antifungal efficacy of garlic EO and its major components, diallyl trisulfide and its nanoemulsions against wood-rotting fungi, Trametes hirsuta ...
Hongjia Liu
exaly +4 more sources
Diallyl Disulfide and Diallyl Trisulfide in Garlic as Novel Therapeutic Agents to Overcome Drug Resistance in Breast Cancer [PDF]
Journal of Pharmaceutical Analysis, 2022 Breast cancer is one of the leading causes of cancer-related deaths in women worldwide. It is a cancer that originates from the mammary ducts and involves mutations in multiple genes.
Rama Rao Malla +2 more
exaly +4 more sources
The Potential of Diallyl Trisulfide for Cancer Prevention and Treatment, With Mechanism Insights [PDF]
Frontiers in Cell and Developmental BiologyCancer has become an important public health problem worldwide, and there is currently a lack of effective treatment and prevention strategies. Natural plant active ingredients have been proven to be a safe and highly promising method for preventing and ...
Zhaofeng Liang, Jiajia Song, Longtao Jin
exaly +4 more sources
Recent Research Advances in Multi-Functional Diallyl Trisulfide (DATS): A Comprehensive Review of Characteristics, Metabolism, Pharmacodynamics, Applications, and Drug Delivery Systems [PDF]
International Journal of NanomedicineMaoru Wang,1,* Jiangping Yu,2,* Hui Xu,3 Kexin Xu,3 Muhammad Sohail,4 Jisheng Wang,1 Hong Ning,2 Jianqiao Zhang,5 Bin Yu2 1Drug Dispensing Department, The Third Hospital of Mianyang, Sichuan Mental Health Center, Mianyang, Sichuan, People’s ...
Hui Xu, Bin Yu
exaly +4 more sources
Diallyl Trisulfide Causes Male Infertility with Oligoasthenoteratospermia in Sitotroga cerealella through the Ubiquitin–Proteasome Pathway [PDF]
Cells, 2023 Essential oils extracted from plant sources along with their biologically active components may have negative effects on insects. Diallyl trisulfide (DAT) is an active component of garlic essential oil, and it exhibits multi-targeted activity against ...
Sakhawat Shah +8 more
doaj +2 more sources
Activation of PI3K/Akt mediates the protective effect of diallyl trisulfide on doxorubicin induced cardiac apoptosis [PDF]
Current Research in Toxicology, 2023 Diallyl trisulfide (DATS), an organosulfide compound derived from garlic, is renowned for its potent antioxidant properties, particularly in countering the generation of reactive oxygen species (ROS).
Su-Ying Wen +5 more
doaj +2 more sources
Diallyl trisulfide improves spinal cord ischemia–reperfusion injury damage by activating AMPK to stabilize mitochondrial function [PDF]
Journal of Orthopaedic Surgery and Research, 2023 Background Spinal cord ischemia–reperfusion injury (SCII) is a catastrophic event, which can cause paraplegia in severe cases. In the reperfusion stage, oxidative stress was up-regulated, which aggravated the injury and apoptosis of neurons.
Yang Sun +9 more
doaj +2 more sources
Folic Acid Functionalized Diallyl Trisulfide–Solid Lipid Nanoparticles for Targeting Triple Negative Breast Cancer [PDF]
Molecules, 2023 DATS (diallyl trisulfide), an anti-oxidant and cytotoxic chemical derived from the plant garlic, has been found to have potential therapeutic activity against triple-negative breast cancer (TNBC).
Anindita De +6 more
doaj +2 more sources
Diallyl Trisulfide, a Biologically Active Component of Garlic Essential Oil, Decreases Male Fertility in Sitotroga cerealella by Impairing Dimorphic Spermatogenesis, Sperm Motility and Lipid Homeostasis [PDF]
Cells, 2023 Diallyl trisulfide (DAT) is a biologically active component of garlic essential oil and exhibits multi-targeted activity against many organisms. The current study tested the capacity of DAT to decrease the male fertility of Sitotroga cerealella.
Sakhawat Shah +8 more
doaj +2 more sources
Diallyl Trisulfide Enhances the Survival of Multiterritory Perforator Skin Flaps [PDF]
Frontiers in Pharmacology, 2022 The multiterritory perforator flap is one of the widest flap patterns used to repair tissue defects. However, flap necrosis of the distal part is still a challenging issue for plastic surgeons.
Chengji Dong +29 more
doaj +2 more sources