Antimicrobial Effect and the Mechanism of Diallyl Trisulfide against Campylobacter jejuni [PDF]
Antibiotics, 2021 Campylobacter jejuni is an important foodborne pathogen causing campylobacteriosis. It can infect humans through the consumption of contaminated chicken products or via the direct handling of animals.
Yuanyue Tang +5 more
doaj +5 more sources
Garlic Derived Diallyl Trisulfide in Experimental Metabolic Syndrome: Metabolic Effects and Cardioprotective Role [PDF]
International Journal of Molecular Sciences, 2020 This study aimed to examine the effects of diallyl trisulfide (DATS), the most potent polysulfide derived from garlic, on metabolic syndrome and myocardial function in rats with metabolic syndrome (MetS). For that purpose, we used 36 male Wistar albino rats divided into control rats, rats with MetS and MetS rats treated with 40 mg/kg of DATS every ...
Jovana V Bradic +2 more
exaly +8 more sources
Diallyl Trisulfide Attenuates Ischemia-Reperfusion-Induced ER Stress and Kidney Dysfunction in Aged Female Mice [PDF]
CellsIschemia-reperfusion injury (IRI) is a common cause of acute kidney injury (AKI) in the aging population. Gender studies show that aging is associated with loss of protection from AKI in the female population.
Sathnur Pushpakumar +5 more
doaj +3 more sources
Diallyl Trisulfide Protects Rat Brain Tissue against the Damage Induced by Ischemia-Reperfusion through the Nrf2 Pathway [PDF]
Antioxidants, 2019 Stroke is a public health problem due to its high mortality and disability rates; despite these, the pharmacological treatments are limited. Oxidative stress plays an important role in cerebral damage in stroke and the activation of the nuclear factor ...
Carlos A. Silva-Islas +5 more
doaj +3 more sources
Diallyl Trisulfide and Cardiovascular Health: Evidence and Potential Molecular Mechanisms. [PDF]
Int J Mol SciTraditionally, garlic has a valuable role in preventing and reducing the incidence of many diseases and pathophysiological disorders. Consequently, some researchers have focused on the beneficial cardiovascular properties of diallyl trisulfide (DATS), the most potent polysulfide isolated from garlic.
Novakovic J +5 more
europepmc +4 more sources
Keap1 cysteine 288 as a potential target for diallyl trisulfide-induced Nrf2 activation. [PDF]
PLoS ONE, 2014 Diallyl sulfide, diallyl disulfide, and daillyl trisulfide (DATS) are major volatile components of garlic oil. In this study, we assessed their relative potency in inducing antioxidant enzyme expression.
Sanghyun Kim +7 more
doaj +5 more sources
Diallyl Trisulfide Inhibits Platelet Aggregation through the Modification of Sulfhydryl Groups
Journal of Agricultural and Food Chemistry, 2020 Diallyl trisulfide (DATS) is a secondary metabolite of allicin, a volatile organosulfur flavoring compound generated by the crushing of garlic. These compounds have various medicinal effects such as antiplatelet activity. In this study, we demonstrated for the first time the cellular mechanism involved in the inhibition of platelet aggregation by DATS ...
Takashi Hosono +4 more
core +4 more sources
VALIDATION AND ANALYSIS OF DIALLYL DISULFIDE AND DIALLYL TRISULFIDE IN GARLIC (ALLIUM SATIVUM L.) USING GAS CHROMATOGRAPHY [PDF]
International Journal of Applied Pharmaceutics, 2020 Objective: The purpose of this research was to optimize and validate a method for measuring the levels of diallyl disulfide (DADS) and diallyl trisulfide(DATS) in garlic and single clove garlic.Methods: The analysis was performed using gas chromatography (GC) equipped with an HP-1 column and a flame ionization detector.
HARMITA HARMITA +2 more
core +4 more sources
Diallyl trisulfide inhibited tobacco smoke-mediated bladder EMT and cancer stem cell marker expression via the NF-κB pathway [PDF]
Journal of International Medical Research, 2021 Objective This study examined the effect of the NF-κB pathway on tobacco smoke-elicited bladder epithelial–mesenchymal transition (EMT) and cancer stem cell (CSC) marker expression in vivo .
Hao Geng +8 more
doaj +2 more sources
Antiviral activity of diallyl trisulfide against H9N2 avian influenza virus infection in vitro and in vivo [PDF]
Virology Journal, 2021 Background Diallyl trisulfide (DATS) is a garlic-derived organosulfur compound. As it has been shown to have anti-viral activity, we hypothesized that it may alleviate infections caused by H9N2 avian influenza virus (AIV), which is prevalent in poultry ...
Le Ming +4 more
doaj +2 more sources