Results 41 to 50 of about 8,485 (177)

Antifungal activity, antibiofilm and synergic effect of diallyl disulfide and diallyl trisulfide against Candida albicans

Research, Society and Development, 2022
The objective of the present study was to determine the antifungal activity, antibiofilm and synergic effect of the compounds diallyl disulfide and diallyl trisulfide in combination with antifungal agents against clinical isolates of Candida albicans, including also a computational study.
Rafael Pereira, Guilherme Mendes Prado, Raquel Oliveira dos Santos Fontenelle, Francisco César Barroso Barbosa, Hélcio Silva dos Santos, Emmanuel Silva Marinho, Márcia Machado Marinho, Selene Maia de Morais   +7 more
openaire   +1 more source

The Effect of Diallyl Polysulfanes on Cellular Signaling Cascades

Natural Product Communications, 2012
Diallyl polysulfanes, such as diallyl trisulfide and diallyl tetrasulfide, are regarded as a group of potential chemopreventive compounds as they have been proven to be effective inhibitors of cancer cells.
Mathias Montenarh, Nathaniel E. B. Saidu
doaj   +1 more source

Bioactive Compounds and Biological Functions of Garlic (Allium sativum L.)

Foods, 2019
Garlic (Allium sativum L.) is a widely consumed spice in the world. Garlic contains diverse bioactive compounds, such as allicin, alliin, diallyl sulfide, diallyl disulfide, diallyl trisulfide, ajoene, and S-allyl-cysteine. Substantial studies have shown
Ao Shang, Shi-Yu Cao, Xiao-Yu Xu, Ren-You Gan, Guo-Yi Tang, Harold Corke, Vuyo Mavumengwana, Hua-Bin Li   +7 more
doaj   +1 more source

Scientific Opinion on Flavouring Group Evaluation 74, Revision 4 (FGE.74Rev4): Consideration of aliphatic sulphides and thiols evaluated by JECFA (53rd and 61st meeting) structurally related to aliphatic and alicyclic mono‐, di‐, tri‐ and polysulphides with or without additional oxygenated functional groups from chemical group 20 evaluated by EFSA in FGE.08Rev5

EFSA Journal, 2018
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to consider evaluations of flavouring substances assessed since 2000 by the Joint FAO/WHO Expert Committee on Food Additives
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF), Vittorio Silano, Claudia Bolognesi, Laurence Castle, Kevin Chipman, Jean‐Pierre Cravedi, Karl‐Heinz Engel, Paul Fowler, Roland Franz, Konrad Grob, Rainer Gürtler, Trine Husøy, Sirpa Kärenlampi, Maria Rosaria Milana, Karla Pfaff, Gilles Riviere, Jannavi Srinivasan, Maria de Fátima Tavares Poças, Christina Tlustos, Detlef Wölfle, Holger Zorn, Romualdo Benigni, Leon Brimer, Gerard Mulder, Agneta Oskarsson, Camilla Svendsen, Jan van Benthem, Maria Anastassiadou, Siiri Saarma, Wim Mennes   +29 more
doaj   +1 more source

Role of Bim in diallyl trisulfide‐induced cytotoxicity in human cancer cells [PDF]

Journal of Cellular Biochemistry, 2011
AbstractThe aim of this study was to investigate the effect of garlic constituent diallyl trisulfide (DATS) on the cell‐death signaling pathway in a human breast cell line (MDA‐MB‐231). We observed that DATS (10–100 µM) treatment resulted in dose‐ and time‐dependent cytotoxicity.
Byeong-Chel, Lee, Bae-Hang, Park, Seog-Young, Kim, Yong J, Lee   +3 more
openaire   +2 more sources

Chemical characterization of the Allium sativum and Origanum vulgare essential oils and their inhibition effect on the growth of some food pathogens

Revista Brasileira de Plantas Medicinais, 2014
This study sought to evaluate the chemical composition of the Allium sativum and Origanum vulgare essential oils and their effect on the growth inhibition of microorganisms, such as P. aeruginosa, S. Choleraesuis, A. flavus, A.
A.C.T. Mallet, M.G Cardoso, P.E. Souza, S.M.F. Machado, M.A. Andrade, D.L. Nelson, R.H. Piccoli, C.G Pereira   +7 more
doaj   +1 more source

The organosulfides diallyl sulfide, diallyl disulfide, and diallyl trisulfide accelerate benzo(a)pyrene metabolism in MCF‐10A cells

The FASEB Journal, 2012
Benzo(a)pyrene (BaP) is a naturally and anthropogenically produced carcinogen created during the incomplete combustion of organic material. BaP is considered a dietary, occupational, and environmental carcinogen, and BaP‐associated adducts have been found in the breast tissue and milk of women.
Candace C. Moyler, Yasmeen Nkrumah-Elie, William Dennis, Alicia Hudson, Rasha Hammamieh, Selina Darling-Reed   +5 more
openaire   +1 more source

Diallyl Trisulfide Is a Fast H₂S Donor, but Diallyl Disulfide Is a Slow One: The Reaction Pathways and Intermediates of Glutathione with Polysulfides

, 2016
Diallyl trisulfide (DATS) reacts rapidly with glutathione (GSH) to release H2S through thiol–disulfide exchange followed by allyl perthiol reduction by GSH.
Dong Liang (120479), Haixia Wu (296640), Ming Wah Wong (1556854), Dejian Huang (413516)   +3 more
core   +1 more source

H2S-Donating trisulfide linkers confer unexpected biological behaviour to poly(ethylene glycol)-cholesteryl conjugates [PDF]

, 2020
Inspired by the properties of the naturally occurring HS donor, diallyl trisulfide (DATS, extracted from garlic), the biological behaviour of trisulfide-bearing PEG-conjugates was explored.
Davis, Thomas P., Whittaker, Michael R., Ercole, Francesca, Li, Yuhuan, Quinn, John F., Francesca Ercole, John F. Quinn, Michael R. Whittaker, Yuhuan Li, Thomas P. Davis   +9 more
core   +1 more source

Chemical Composition and Antimicrobial Activity of the Essential Oil from Consumed in Xishuangbanna, Southwest China

Natural Product Communications, 2014
The essential oil from the rhizomes of Allium hookeri Thwaites, obtained by simultaneous distillation extraction, was analyzed by GC-MS. Di-2-propenyl trisulfide (31.8%), diallyl disulfide (28.4%), and dipropyl trisulfide (8.4%) were the main ...
Ren Li, Yuan-Fei Wang, Qian Sun, Hua-Bin Hu   +3 more
doaj   +1 more source