Results 41 to 50 of about 12,487 (210)

Diallyl trisulfide alleviates chemotherapy sensitivity of ovarian cancer via the AMPK/SIRT1/PGC1α pathway. [PDF]

Cancer Sci, 2023
Platinum‐based chemotherapy promotes drug resistance in ovarian cancer. We investigated the antichemoresistance characteristics of diallyl trisulfide (DATS) in cisplatin‐resistant ovarian cancer cells, in vitro and in vivo.
Wang Z, Yan Y, Lou Y, Huang X, Liu L, Weng Z, Cui Y, Wu X, Cai H, Chen X, Ji Y.   +10 more
europepmc   +2 more sources

The Garlic Compound, Diallyl Trisulfide, Attenuates Benzo[a]Pyrene-Induced Precancerous Effect through Its Antioxidant Effect, AhR Inhibition, and Increased DNA Repair in Human Breast Epithelial Cells. [PDF]

Nutrients
Exposure to B[a]P, the most characterized polycyclic aromatic hydrocarbon, significantly increases breast cancer risk. Our lab has previously reported that diallyl trisulfide (DATS), a garlic organosulfur compound (OSC) with chemopreventive and cell ...
Ferguson DT, Taka E, Messeha S, Flores-Rozas H, Reed SL, Redmond BV, Soliman KFA, Kanga KJW, Darling-Reed SF.   +8 more
europepmc   +2 more sources

Allicin and Digestive System Cancers: From Chemical Structure to Its Therapeutic Opportunities

Frontiers in Oncology, 2021
Digestive system cancer tumors are one of the major causes of cancer-related fatalities; the vast majority of them are colorectal or gastric malignancies. Epidemiological evidence confirmed that allium-containing food, such as garlic, reduces the risk of
Mahshad Sarvizadeh, Omid Hasanpour, Zari Naderi Ghale-Noie, Samaneh Mollazadeh, Mohammad Rezaei, Hossein Pourghadamyari, Mohammadjaber Masoud Khooy, Michael Aschner, Haroon Khan, Nima Rezaei, Nima Rezaei, Nima Rezaei, Layla Shojaie, Hamed Mirzaei   +13 more
doaj   +1 more source

Nontoxic effects of thymol, carvacrol, cinnamaldehyde, and garlic oil on dung beetles: A potential alternative to ecotoxic anthelmintics.

PLoS ONE, 2023
The sustainability of the traditional extensive livestock sector will only be possible if healthy dung-decomposing insect communities are preserved. However, many current pharmaceutical anthelmintics are harmful to dung beetles, their presence can have a
José R Verdú, Vieyle Cortez, Rocío Rosa-García, Antonio J Ortiz, Urcesino García-Prieto, Jean-Pierre Lumaret, Carmelo García Romero, Francisco Sánchez-Piñero   +7 more
doaj   +1 more source

Apoptotic pathway induced by diallyl trisulfide in pancreatic cancer cells [PDF]

World Journal of Gastroenterology, 2014
To investigate the effects of diallyl trisulfide (DATS), a garlic-derived organosulfur compound, in pancreatic cancer cells.Human pancreatic cancer cells with wild-type p53 gene (Capan-2) and normal pancreatic epithelial cells (H6C7) were cultured in RPMI1640. DATS was prepared at a concentration of 100 μmol/L.
Hong-Bing, Ma, Shan, Huang, Xiao-Ran, Yin, Yang, Zhang, Zheng-Li, Di   +4 more
openaire   +2 more sources

Impact of harvest date on the content of volatile components in garlic [PDF]

Journal of Central European Agriculture, 2020
The aim of this study was to define optimal harvesting date of garlic cv. 'Istarski crveni' by comparing the amount of volatile compounds as one of quality indicators.
Iva Bazon, Igor Lukic, Dean Ban, Ivana Horvat, Bernard Prekalj, Smiljana Goreta Ban   +5 more
doaj   +1 more source

Mechanisms of action by sulphur compounds in Allium sativum. A review

Pharmacological Research - Modern Chinese Medicine, 2023
Background: Allium sativum, the bulbous perennial plant of the Alliaceae family has been utilized as a very valuable remedy in the management of numerous diseases even from time immemorial. The plant exhibits antimicrobial activities over a wide range of
Agatha Ngukuran Jikah, Great Iruoghene Edo   +1 more
doaj   +1 more source

Chemical Constituents, In Vitro Antioxidant Activity and In Silico Study on NADPH Oxidase of Allium sativum L. (Garlic) Essential Oil

Antioxidants, 2021
Allium sativum L., also known as garlic, is a perennial plant widely used as a spice and also considered a medicinal herb since antiquity. The aim of this study was to determine by gas chromatography–mass spectrometry (GC–MS) the chemical profile ...
Oscar Herrera-Calderon, Luz Josefina Chacaltana-Ramos, Irma Carmen Huayanca-Gutiérrez, Majed A. Algarni, Mohammed Alqarni, Gaber El-Saber Batiha   +5 more
doaj   +1 more source

Diallyl Trisulfide Promotes Placental Angiogenesis by Regulating Lipid Metabolism and Alleviating Inflammatory Responses in Obese Pregnant Mice. [PDF]

Nutrients, 2022
The placental tissue serves as an exchanger between the mother and the fetus during pregnancy in mammals. Proper placental angiogenesis is central to the health of both the mother and the growth and development of the fetus.
Wang M, Wang Z, Miao Y, Wei H, Peng J, Zhou Y.   +5 more
europepmc   +2 more sources

Valorization of the Hydrolate Byproduct from the Industrial Extraction of Purple Alium sativum Essential Oil as a Source of Nematicidal Products

Life, 2022
The hydrolate byproduct resulting from the industrial essential oil extraction of Spanish purple garlic has been studied against the root-knot nematode Meloidogyne javanica by in vitro and in vivo bioassays.
Alberto Galisteo, Azucena González-Coloma, Purificación Castillo, María Fe Andrés   +3 more
doaj   +1 more source