Results 21 to 30 of about 12,487 (210)

Diallyl trisulfide induces apoptosis in Jurkat cells by the modification of cysteine residues in thioredoxin [PDF]

Bioscience, Biotechnology and Biochemistry, 2014
Abstract We reported the regulation of protein function by oxidative modification of the specific cysteine residue(s) by diallyl trisulfide (DATS). In this study, we examined if DATS modifies the cysteine residue of thioredoxin (Trx) by urea-polyacryl amide gel electrophoresis. DATS modified two specific cysteine residues in Trx and this
Takashi Hosono, Toyohiko Ariga, Taiichiro Seki   +2 more
exaly   +3 more sources

Diallyl trisulfide modulated autophagy in isoproterenol induced acute myocardial infarction

Clinical Phytoscience, 2022
Background Acute myocardial infarction (AMI) is the most serious manifestation of coronary artery disease. The initial ischemia in AMI causes biochemical and metabolic alterations in cardiomyocytes.
Nahla E. El-Ashmawy, Naglaa F. Khedr, Mohamed N. Shaban, Ghada M. Al-Ashmawy   +3 more
doaj   +2 more sources

Diallyl Trisulfide Acts as a Soil Disinfestation Against the Ilyonectria destructans through Inducing the Burst of Reactive Oxygen Species

Journal of Agricultural and Food Chemistry
Soil-borne diseases represent an impediment to the sustainable development of agriculture. A soil-borne disease caused by Ilyonectria destructans severely impacts Panax species, and soil disinfestation has proven to be an effective management approach ...
Jing Zhao (21160), Jiaqing Wu (9176963), Tao He (23919), Shusheng Zhu (313806), Yixiang Liu (1693243), Min Yang (146229), Yingpin Liu (18399437), Xinyue Mei (680850), Jinyu Liu (140304), Junwei Sun (204047)   +9 more
core   +3 more sources

Keap1 Cysteine 288 as a Potential Target for Diallyl Trisulfide-Induced Nrf2 Activation

PLoS ONE, 2014
Diallyl sulfide, diallyl disulfide, and daillyl trisulfide (DATS) are major volatile components of garlic oil. In this study, we assessed their relative potency in inducing antioxidant enzyme expression. Among the three organosulfur compounds, DATS was found to be most potent in inducing heme oxygenase-1 (HO-1) andquinone oxidoreductase-1 (NQO1) in ...
Sanghyun Kim, Hee-Geum Lee, Sin-Aye Park, Joydeb Kumar Kundu, Young-Sam Keum, Young-Nam Cha, Hye-Kyung Na, Young-Joon Surh   +7 more
openaire   +5 more sources

Allobaculum plays a predominant role in the activation of brown fat tissue by diallyl trisulfide

Food Frontiers
Diallyl trisulfide (DATS) is a bioactive compound in garlic. It has been reported to ameliorate obesity by preventing adipogenesis and lipogenesis in white adipose tissue. But we found DATS could also activate brown adipose tissue (BAT) in high‐fat diet (
Jia Xu, Jiantang Wang, Kunlun Huang, Ruxin Gao, Ye Xu, Xiaoyun He, Yanzhou Hu, Bingxin Huangfu, Ruiqi Zhang, Yunbo Luo, Teng Wang   +10 more
core   +2 more sources

Effect of Diallyl Trisulfide on Ischemic Tissue Injury and Revascularization in a Diabetic Mouse Model. [PDF]

J Cardiovasc Pharmacol, 2018
Background and Objective: Allitridin [diallyl trisulfide (DATS)] is an extract from garlic (Allium sativum) that putatively improves endothelial function and is protective against cardiovascular diseases. Endothelial dysfunction after tissue ischemia in diabetic patients is partially due to poor angiogenic response.
Yang HB, Liu HM, Yan JC, Lu ZY.
europepmc   +4 more sources

Diallyl disulfide and diallyl trisulfide protect endothelial nitric oxide synthase against damage by oxidized low‐density lipoprotein

Molecular Nutrition and Food Research, 2010
AbstractGarlic is viewed as an effective health food against atherosclerosis. In this study, we examined whether diallyl disulfide (DADS) and diallyl trisulfide (DATS) protect endothelial nitric oxide synthase (eNOS) activation against oxidized LDL (ox‐LDL) insult and through what mechanism.
Cheng-Tzu Liu, Lee-Yan Sheen, Haw-Wen Chen   +2 more
exaly   +4 more sources

Diallyl Trisulfide Attenuates Ischemia-Reperfusion-Induced ER Stress and Kidney Dysfunction in Aged Female Mice. [PDF]

Cells
Ischemia-reperfusion injury (IRI) is a common cause of acute kidney injury (AKI) in the aging population. Gender studies show that aging is associated with loss of protection from AKI in the female population.
Pushpakumar S, Juin SK, Almarshood H, Gondim DD, Ouseph R, Sen U.   +5 more
europepmc   +2 more sources

Diallyl Trisulfide From Garlic Regulates RAB18 Phase Separation to Inhibit Lipophagy and Induce Cuproptosis in Hepatic Stellate Cells for Antifibrotic Effects. [PDF]

Adv Sci (Weinh)
Liver fibrosis, a common pathological process, severely impacts human health, yet effective treatments are lacking. Cuproptosis, a newly discovered form of cell death induced by copper ions, triggers cytotoxic stress through lipoylated protein ...
Tian H, Sun S, Qiu X, Wang J, Gao Y, Chen J, Han X, Bao Z, Guo X, Sun Y, Lin Y, Hu M, Zhang F, Zhang Z, Wang F, Zheng S, Shao J.   +16 more
europepmc   +2 more sources

Diallyl trisulfide improves spinal cord ischemia-reperfusion injury damage by activating AMPK to stabilize mitochondrial function. [PDF]

J Orthop Surg Res, 2023
Background Spinal cord ischemia–reperfusion injury (SCII) is a catastrophic event, which can cause paraplegia in severe cases. In the reperfusion stage, oxidative stress was up-regulated, which aggravated the injury and apoptosis of neurons.
Sun Y, Xu D, Yang W, Zhang H, Su Y, Gao B, Zou X, Zhong Y, Sun H, Xiang L.   +9 more
europepmc   +2 more sources