Attenuative Effect of Diallyl Trisulfide on Caspase Activity in TNF-α-induced Triple Negative Breast Cancer Cells. [PDF]
Background/Aim: Diallyl trisulfide (DATS) has been shown to prevent and inhibit carcinogenesis in cancer cells. We have previously shown DATS’s ability to decrease the percentage of viable cells, inhibit cell migration and modulate genes involved in the ...
Kanga KJW +6 more
europepmc +2 more sources
Activation of PI3K/Akt mediates the protective effect of diallyl trisulfide on doxorubicin induced cardiac apoptosis. [PDF]
Graphical ...
Wen SY +5 more
europepmc +2 more sources
Prediction of the mechanism for the combination of diallyl trisulfide and cisplatin against gastric cancer: a network pharmacology study and pharmacological evaluation. [PDF]
Background: In this research, we aimed to explore the efficacy of diallyl trisulfide (DATS) combined with cisplatin (DDP) for gastric cancer treatment and its underlying mechanism based on network pharmacology.
Lv H +5 more
europepmc +2 more sources
Diallyl Trisulfide Enhances Doxorubicin Chemosensitivity by Inhibiting the Warburg Effect and Inducing Apoptosis in Breast Cancer Cells. [PDF]
Breast cancer is the leading cause of cancer-related mortality among women. Doxorubicin (DOX) is the major chemotherapeutic agent for breast cancer treatment, but its efficacy is hindered by chemoresistance and dose-dependent toxicity.
Chang CM +9 more
europepmc +2 more sources
Diallyl Trisulfide, a Biologically Active Component of Garlic Essential Oil, Decreases Male Fertility in Sitotroga cerealella by Impairing Dimorphic Spermatogenesis, Sperm Motility and Lipid Homeostasis. [PDF]
Diallyl trisulfide (DAT) is a biologically active component of garlic essential oil and exhibits multi-targeted activity against many organisms. The current study tested the capacity of DAT to decrease the male fertility of Sitotroga cerealella.
Shah S +8 more
europepmc +2 more sources
Bioactivity Impact of Essential Oils Allium sativum L. and Citrus reticulata L. Against Stored Product Insects Tribolium castaneum (Herbst) and Rhyzopertha dominica (F.) [PDF]
This study was conducted to estimate the impact of contact and fumigation toxicity of garlic(Allium sativum L.)and mandarin (Citrus reticulata L.) essential oilsagainst two of stored product insects Tribolium castaneum (Herbst) and Rhyzopertha dominica(F.
M. Zayed, A. Omar
doaj +1 more source
Diallyl Trisulfide Induces ROS-Mediated Mitotic Arrest and Apoptosis and Inhibits HNSCC Tumor Growth and Cancer Stemness. [PDF]
Simple Summary Head and neck cancers arise in the mouth, pharynx, salivary glands, and larynx, and most of these cancers are squamous cell carcinomas. Causative agents for head and neck squamous cell carcinoma (HNSCC) include tobacco-derived carcinogens,
Mathan SV +4 more
europepmc +2 more sources
Integrative mRNA and microRNA Analysis Exploring the Inducing Effect and Mechanism of Diallyl Trisulfide (DATS) on Potato against Late Blight. [PDF]
Potato late blight, caused by Phytophthora infestans, leads to a significant reduction in the yield and value of potato. Biocontrol displays great potential in the suppression of plant diseases.
Jian Y +8 more
europepmc +2 more sources
Background Accumulating evidence suggests that hydrogen sulfide ( H2S ), an endogenously produced gaseous molecule, plays a critical role in the regulation of cardiovascular homeostasis. However, little is known about its role in lymphangiogenesis. Thus,
Junya Suzuki +10 more
doaj +1 more source
Molecular Screening of Bioactive Compounds of Garlic for Therapeutic Effects against COVID-19
An outbreak of pneumonia occurred on December 2019 in Wuhan, China, which caused a serious public health emergency by spreading around the globe. Globally, natural products are being focused on more than synthetic ones.
Huma Ashraf +5 more
doaj +1 more source

