Mechanisms of action by sulphur compounds in Allium sativum. A review
Background: Allium sativum, the bulbous perennial plant of the Alliaceae family has been utilized as a very valuable remedy in the management of numerous diseases even from time immemorial. The plant exhibits antimicrobial activities over a wide range of
Agatha Ngukuran Jikah +1 more
doaj +1 more source
Exploring the role and mechanisms of diallyl trisulfide and diallyl disulfide in chronic constriction-induced neuropathic pain in rats. [PDF]
Garlic oil is a rich source of organosulfur compounds including diallyl disulfide and diallyl trisulfide. There have been studies showing the neuroprotective actions of these organosulfur compounds. However, the potential of these organosulfur compounds in neuropathic pain has not been explored.
Wang G +6 more
europepmc +4 more sources
The hydrolate byproduct resulting from the industrial essential oil extraction of Spanish purple garlic has been studied against the root-knot nematode Meloidogyne javanica by in vitro and in vivo bioassays.
Alberto Galisteo +3 more
doaj +1 more source
Impact of harvest date on the content of volatile components in garlic [PDF]
The aim of this study was to define optimal harvesting date of garlic cv. 'Istarski crveni' by comparing the amount of volatile compounds as one of quality indicators.
Iva Bazon +5 more
doaj +1 more source
Allium sativum L., also known as garlic, is a perennial plant widely used as a spice and also considered a medicinal herb since antiquity. The aim of this study was to determine by gas chromatography–mass spectrometry (GC–MS) the chemical profile ...
Oscar Herrera-Calderon +5 more
doaj +1 more source
Diallyl Trisulfide Induces Apoptosis in Breast Ductal Carcinoma In Situ Derived and Minimally Invasive Breast Cancer Cells. [PDF]
Breast ductal carcinoma in situ (DCIS) is a localized form of breast cancer that can progress to invasive breast cancer. Diallyl trisulfide (DATS) is a bioactive compound from Allium vegetables reported to induce anticancer effects in several cancer ...
Stan SD, Abtahi M.
europepmc +2 more sources
Garlic-inspired trisulfide linkers for thiol-stimulated H2S release [PDF]
Garlic-derived polysulfides (e.g., diallyl trisulfide, DATS) act as potent donors of the cell-signalling mediator H2S when exposed to endogenous thiols. Inspired by this chemistry, we incorporated a trisulfide linkage into a conjugate comprising an mPEG ...
Boyd, Ben J. +16 more
core +1 more source
Alzheimer’s disease is the main reason for dementia, which increases with age. Cholinesterase inhibition and antioxidant potentials of extracts and essential oils from bulbs of A.
Songul Karakaya +6 more
doaj +1 more source
Diallyl polysulfides from Allium sativum as immunomodulators, hepatoprotectors, and antimycobacterial agents [PDF]
Mycobacterium tuberculosis remains one of the world's deadliest killers, with an annual death rate of ∼1.5 million. The medicinal effects of garlic have been well documented, and natural products have been shown to have antimycobacterial activity.
Oosthuizen, Carel +10 more
core +1 more source
Antimicrobial properties of garlic oil against human enteric bacteria: evaluation of methodologies and comparisons with garlic oil sulfides and garlic powder. [PDF]
The antimicrobial effects of aqueous garlic extracts are well established but those of garlic oil (GO) are little known. Methodologies for estimating the antimicrobial activity of GO were assessed and GO, GO sulfide constituents, and garlic powder (GP ...
Ross, Z.M. +4 more
core +1 more source

