Diallyl Disulfide and Diallyl Trisulfide in Garlic as Novel Therapeutic Agents to Overcome Drug Resistance in Breast Cancer [PDF]
Journal of Pharmaceutical Analysis, 2022 Breast cancer is one of the leading causes of cancer-related deaths in women worldwide. It is a cancer that originates from the mammary ducts and involves mutations in multiple genes.
Rama Rao Malla +2 more
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Diallyl Disulfide: A Bioactive Garlic Compound with Anticancer Potential [PDF]
Frontiers in Pharmacology, 2022 Cancer is a life-threatening disease caused by the uncontrolled division of cells, which culminates in a solid mass of cells known as a tumor or liquid cancer.
Saikat Mitra +14 more
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Development of a Silicone-Based Polymer Matrix as a Suitable Transdermal Therapeutic System for Diallyl Disulfide [PDF]
Pharmaceuticals, 2022 There is an unmet need for novel therapeutic tools relieving chronic pain. Hydrogen sulfide (H2S) is highly involved in pain processes; however, the development of ideal matrices for sulfide donor compounds remains a great pharmaceutical challenge.
Szabolcs László +4 more
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Diallyl Disulfide Induces Chemosensitization to Sorafenib, Autophagy, and Cell Cycle Arrest and Inhibits Invasion in Hepatocellular Carcinoma [PDF]
Pharmaceutics, 2022 Hepatocellular carcinoma is the seventh most common type of cancer in the world, with limited treatment options. A promising strategy to treat cancer is to associate chemotherapeutics and plant bioactive compounds.
Ana Rita Thomazela Machado +4 more
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Cytotoxic Effects of Nanoliposomal Cisplatin and Diallyl Disulfide on Breast Cancer and Lung Cancer Cell Lines [PDF]
Biomedicines, 2023 Dual drug delivery has become the choice of interest nowadays due to its increased therapeutic efficacy in targeting the tumor site precisely. As quoted in recent literature, it has been known to treat several cancers with an acute course of action. Even
Kaavya Gunasekaran +9 more
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Ameliorative role of diallyl disulfide against glycerol-induced nephrotoxicity in rats [PDF]
Journal of Pharmacy and Bioallied Sciences, 2021 Introduction: This study investigated the role of diallyl disulfide (DADS) against glycerol-induced nephrotoxicity in rats. Moreover, the role of peroxisome proliferator activated receptor-γ (PPAR-γ) in DADS-mediated renoprotection has been explored ...
Ashwani Kumar Sharma +9 more
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Diallyl Disulfide Attenuates Ionizing Radiation-Induced Migration and Invasion by Suppressing Nrf2 Signaling in Non–small-Cell Lung Cancer [PDF]
Dose-Response, 2021 Non–small-cell lung cancer (NSCLC) is the leading cause of cancer-associated deaths. Radiotherapy remains the primary treatment method for NSCLC. Despite great advances in radiotherapy techniques and modalities, recurrence and resistance still limit ...
Shuai Xu +9 more
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Retraction: Diallyl Disulfide Suppresses SRC/Ras/ERK Signaling-Mediated Proliferation and Metastasis in Human Breast Cancer by Up-Regulating miR-34a [PDF]
PLoS ONE, 2023 PLOS ONE Editors.
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Sensory-guided Design of Garlic Using tea and Identification of key active components [PDF]
Food Chemistry: XGarlic is widely used as a condiment, yet its sulfur-derived odor persists long after consumption, often limiting sensory acceptance. Using common dietary components to modulate garlic odor is viewed as a promising sensory-guided design strategy for ...
Yongxian Chen +7 more
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The Combination of Oolonghomobisflavan B and Diallyl Disulfide Induces Apoptotic Cell Death via 67-kDa Laminin Receptor/Cyclic Guanosine Monophosphate in Acute Myeloid Leukemia Cells [PDF]
Current Issues in Molecular BiologyDiallyl disulfide (DADS) is a well-known principal functional component derived from garlic (Allium sativum) that has various health benefits. Previously, we identified a 67-kDa laminin receptor, a receptor for oolong tea polyphenol oolonghomobisflavan B
Jaehoon Bae, Su-Jin Park
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