The Anticancer Effects of the Garlic Organosulfide Diallyl Trisulfide through the Attenuation of B[a]P-Induced Oxidative Stress, AhR Expression, and DNA Damage in Human Premalignant Breast Epithelial (MCF-10AT1) Cells. [PDF]
Int J Mol SciBenzo[a]pyrene (B[a]P) is the most characterized polycyclic aromatic hydrocarbon associated with breast cancer. Our lab previously reported that the organosulfur compound (OSC), diallyl trisulfide (DATS), chemoprevention mechanism works through the ...
Ferguson DT +10 more
europepmc +2 more sources
Mechanisms of Action of Diallyl Trisulfide in Breast Ductal Carcinoma In Situ Cells [PDF]
Curr Dev Nutr, 2020 Stan S, Abtahi M.
europepmc +3 more sources
Lipid-Based Nanoparticle Formulation of Diallyl Trisulfide Chemosensitizes the Growth Inhibitory Activity of Doxorubicin in Colorectal Cancer Model: A Novel In Vitro, In Vivo and In Silico Analysis. [PDF]
Molecules, 2022 Garlic’s main bioactive organosulfur component, diallyl trisulfide (DATS), has been widely investigated in cancer models. However, DATS is not suitable for clinical use due to its low solubility.
Alrumaihi F +11 more
europepmc +2 more sources
Anales del Jardín Botánico de Madrid, 2019 Alzheimer’s disease is the main reason for dementia, which increases with age. Cholinesterase inhibition and antioxidant potentials of extracts and essential oils from bulbs of A.
Songul Karakaya +6 more
doaj +1 more source
Garlic (Allium sativum L.) Bioactives and Its Role in Alleviating Oral Pathologies
Antioxidants, 2021 Garlic (Allium sativa L.) is a bulbous flowering plant belongs to the family of Amaryllidaceae and is a predominant horticultural crop originating from central Asia.
Minnu Sasi +22 more
doaj +1 more source
Antimicrobial properties of garlic oil against human enteric bacteria: evaluation of methodologies and comparisons with garlic oil sulfides and garlic powder. [PDF]
, 2007 The antimicrobial effects of aqueous garlic extracts are well established but those of garlic oil (GO) are little known. Methodologies for estimating the antimicrobial activity of GO were assessed and GO, GO sulfide constituents, and garlic powder (GP ...
Ross, Z.M. +4 more
core +1 more source
Heliyon, 2021 Background: Mosquito control programme using synthetic insecticides has been facing the challenges of resistance development. However, synergistic combinations of plant essential oils (EOs) having different modes of actions and potent lethal toxicity may
Sudarshana Mahanta, Bulbuli Khanikor
doaj +1 more source
Antioxidants, 2021 Organosulfur compounds, phenolic acids and flavonoids in raw and black garlic were determined, and followed by preparation of black garlic nanoemulsion for studying their effects on deoxycorticosterone acetate-salt-induced hypertension and associated ...
Chun-Yu Chen +2 more
doaj +1 more source
Research, Society and Development, 2022 The objective of the present study was to determine the antifungal activity, antibiofilm and synergic effect of the compounds diallyl disulfide and diallyl trisulfide in combination with antifungal agents against clinical isolates of Candida albicans, including also a computational study.
Rafael Pereira +7 more
openaire +1 more source
The Effect of Diallyl Polysulfanes on Cellular Signaling Cascades
Natural Product Communications, 2012 Diallyl polysulfanes, such as diallyl trisulfide and diallyl tetrasulfide, are regarded as a group of potential chemopreventive compounds as they have been proven to be effective inhibitors of cancer cells.
Mathias Montenarh, Nathaniel E. B. Saidu
doaj +1 more source