Results 61 to 70 of about 8,485 (177)

Diallyl trisulfide induces apoptosis in Jurkat cells by the modification of cysteine residues in thioredoxin [PDF]

Bioscience, Biotechnology, and Biochemistry, 2014
Abstract We reported the regulation of protein function by oxidative modification of the specific cysteine residue(s) by diallyl trisulfide (DATS). In this study, we examined if DATS modifies the cysteine residue of thioredoxin (Trx) by urea-polyacryl amide gel electrophoresis. DATS modified two specific cysteine residues in Trx and this
Kazunari, Watanabe, Takashi, Hosono, Kazuhiro, Watanabe, Tomomi, Hosono-Fukao, Toyohiko, Ariga, Taiichiro, Seki   +5 more
openaire   +2 more sources

Phase Separation, Material State, and Condensate Fate in Mammalian Autophagy

Advanced Science, Volume 13, Issue 54, 28 September 2026.
ABSTRACT Biomolecular phase separation has emerged as a key organizing principle in macroautophagy (hereafter autophagy). In mammalian cells, phase‐separated condensates not only serve as substrates for selective degradation, but also act as dynamic platforms for cargo recognition, signaling integration, and autophagosome assembly.
Yuanqiang Lin, Mingran Dai, Enyong Dai, Rui Kang, Daniel J. Klionsky, Daolin Tang, Yu Sun, Ningning Lv, Junnan Jiang   +8 more
wiley   +1 more source

Effects of Black Garlic Extract and Nanoemulsion on the Deoxy Corticosterone Acetate-Salt Induced Hypertension and Its Associated Mild Cognitive Impairment in Rats

Antioxidants, 2021
Organosulfur compounds, phenolic acids and flavonoids in raw and black garlic were determined, and followed by preparation of black garlic nanoemulsion for studying their effects on deoxycorticosterone acetate-salt-induced hypertension and associated ...
Chun-Yu Chen, Tsung-Yu Tsai, Bing-Huei Chen   +2 more
doaj   +1 more source

Mitochondria as the Hub of Apoptosis: A Comprehensive Insight From Mitochondria to Interactions With Other Organelles

MedComm, Volume 7, Issue 9, September 2026.
Mitochondria is the hub of apoptosis in various diseases. The disruption of mitochondrial structure (including membrane rupture, cristae remodeling, and mitochondrial membrane lipid redistribution), the imbalance of mitochondrial dynamics (including fusion and fission, autophagy), the release, disruption, and mutation of mitochondria DNA, as well as ...
Rubin Tan, Jinming Zhao, Rong Wang, Yue Shi, Zaozao Chen, Yixuan Ma, Na Li, Wenqing Duan, Duo Lin, Chunxiang Zhang   +9 more
wiley   +1 more source

Diallyl Trisulfide Modulates Notch Pathway Components in Breast Cancer Cells [PDF]

, 2016
Breast cancer affects one in eight women throughout the course of their lifetimes creating an immediate demand for novel prevention strategies against this disease.
Kiesel, Violet Abigail, Kiesel, Violet
core   +2 more sources

Antimetastatic Therapies of the Polysulfide Diallyl Trisulfide against Triple-Negative Breast Cancer (TNBC) via Suppressing MMP2/9 by Blocking NF-κB and ERK/MAPK Signaling Pathways.

PLoS ONE, 2015
BackgroundMigration and invasion are two crucial steps of tumor metastasis. Blockage of these steps may be an effective strategy to reduce the risk. The objective of the present study was to investigate the effects of diallyl trisulfide (DATS), a natural
Yuping Liu, Pingting Zhu, Yingyu Wang, Zhonghong Wei, Li Tao, Zhijie Zhu, Xiaobo Sheng, Siliang Wang, Junshan Ruan, Zhaoguo Liu, Yuzhu Cao, Yunlong Shan, Lihua Sun, Aiyun Wang, Wenxing Chen, Yin Lu   +15 more
doaj   +1 more source

Diallyl Trisulfide Protects Rats from Carbon Tetrachloride-Induced Liver Injury [PDF]

The Journal of Nutrition, 2009
Alk(en)yl sulfides have been found to be responsible for the anticancer, antithrombotic, and antioxidant effects of garlic. We sought to identify the most potent structure of sulfides that exhibits a hepatoprotective effect against carbon tetrachloride (CCl(4))-induced acute liver injury in rats. Rats were pretreated with diallyl trisulfide (DATS) i.g.
Tomomi, Hosono-Fukao, Takashi, Hosono, Taiichiro, Seki, Toyohiko, Ariga   +3 more
openaire   +2 more sources

The Therapeutic Potential of H2S‐Releasing Platforms in Cardiovascular Applications

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 8, August 2026.
The Therapeutic Potential of H2S‐Releasing Platforms. ABSTRACT Once known as a toxic gas, hydrogen sulfide (H2S) is now making its way into many therapeutic applications. Similar to its other fellow endogenous gasotransmitters, nitric oxide and carbon monoxide, H2S is a small gas with a short half‐life, making it extremely capable of penetrating ...
Tia N. Shorter, Elizabeth J. Brisbois
wiley   +1 more source

Wild chive oil is an extremely effective larvicide against malaria mosquito vector Anopheles stephensi

Asian Pacific Journal of Tropical Medicine, 2019
Objective: To assess the chemical composition and mosquito larvicidal potentials of essential oil of wild chive (Allium schoenoprasum L.) against Anopheles stephensi. Methods: In the search for an environmentally safer alternative mosquitoes control, the
Alireza Sanei-Dehkordi, Moussa Soleimani-Ahmadi, Yaser Salim Abadi, Azim Paksa   +3 more
doaj   +1 more source

Antibacterial Effect of (2E,2E)-4,4-Trisulfanediylbis(but-2-enoic acid) against Staphylococcus aureus. [PDF]

PLoS ONE, 2018
A new highly active molecule, (2E, 2E)-4,4-trisulfanediylbis(but-2-enoic acid) (TSDB), was designed and synthesized through comparative molecular field analysis with the diallyl trisulfide structure of garlic.
Tao Wu, Yina Huang, Yijun Chen, Min Zhang   +3 more
doaj   +1 more source