Results 61 to 70 of about 12,487 (210)

Bioactive Compounds and Biological Functions of Garlic (Allium sativum L.)

Foods, 2019
Garlic (Allium sativum L.) is a widely consumed spice in the world. Garlic contains diverse bioactive compounds, such as allicin, alliin, diallyl sulfide, diallyl disulfide, diallyl trisulfide, ajoene, and S-allyl-cysteine. Substantial studies have shown
Ao Shang, Shi-Yu Cao, Xiao-Yu Xu, Ren-You Gan, Guo-Yi Tang, Harold Corke, Vuyo Mavumengwana, Hua-Bin Li   +7 more
doaj   +1 more source

Scientific Opinion on Flavouring Group Evaluation 74, Revision 4 (FGE.74Rev4): Consideration of aliphatic sulphides and thiols evaluated by JECFA (53rd and 61st meeting) structurally related to aliphatic and alicyclic mono‐, di‐, tri‐ and polysulphides with or without additional oxygenated functional groups from chemical group 20 evaluated by EFSA in FGE.08Rev5

EFSA Journal, 2018
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to consider evaluations of flavouring substances assessed since 2000 by the Joint FAO/WHO Expert Committee on Food Additives
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF), Vittorio Silano, Claudia Bolognesi, Laurence Castle, Kevin Chipman, Jean‐Pierre Cravedi, Karl‐Heinz Engel, Paul Fowler, Roland Franz, Konrad Grob, Rainer Gürtler, Trine Husøy, Sirpa Kärenlampi, Maria Rosaria Milana, Karla Pfaff, Gilles Riviere, Jannavi Srinivasan, Maria de Fátima Tavares Poças, Christina Tlustos, Detlef Wölfle, Holger Zorn, Romualdo Benigni, Leon Brimer, Gerard Mulder, Agneta Oskarsson, Camilla Svendsen, Jan van Benthem, Maria Anastassiadou, Siiri Saarma, Wim Mennes   +29 more
doaj   +1 more source

Antibacterial Effect of (2E,2E)-4,4-Trisulfanediylbis(but-2-enoic acid) against Staphylococcus aureus. [PDF]

PLoS ONE, 2018
A new highly active molecule, (2E, 2E)-4,4-trisulfanediylbis(but-2-enoic acid) (TSDB), was designed and synthesized through comparative molecular field analysis with the diallyl trisulfide structure of garlic.
Tao Wu, Yina Huang, Yijun Chen, Min Zhang   +3 more
doaj   +1 more source

Role of Bim in diallyl trisulfide‐induced cytotoxicity in human cancer cells [PDF]

Journal of Cellular Biochemistry, 2011
AbstractThe aim of this study was to investigate the effect of garlic constituent diallyl trisulfide (DATS) on the cell‐death signaling pathway in a human breast cell line (MDA‐MB‐231). We observed that DATS (10–100 µM) treatment resulted in dose‐ and time‐dependent cytotoxicity.
Byeong-Chel, Lee, Bae-Hang, Park, Seog-Young, Kim, Yong J, Lee   +3 more
openaire   +2 more sources

Chemical characterization of the Allium sativum and Origanum vulgare essential oils and their inhibition effect on the growth of some food pathogens

Revista Brasileira de Plantas Medicinais, 2014
This study sought to evaluate the chemical composition of the Allium sativum and Origanum vulgare essential oils and their effect on the growth inhibition of microorganisms, such as P. aeruginosa, S. Choleraesuis, A. flavus, A.
A.C.T. Mallet, M.G Cardoso, P.E. Souza, S.M.F. Machado, M.A. Andrade, D.L. Nelson, R.H. Piccoli, C.G Pereira   +7 more
doaj   +1 more source

Garlic-inspired trisulfide linkers for thiol-stimulated H2S release [PDF]

, 2017
Garlic-derived polysulfides (e.g., diallyl trisulfide, DATS) act as potent donors of the cell-signalling mediator H2S when exposed to endogenous thiols. Inspired by this chemistry, we incorporated a trisulfide linkage into a conjugate comprising an mPEG ...
Boyd, Ben J., Whittaker, Michael R, Francesca Ercole, John F. Quinn, Halls, Michelle L., Michelle L. Halls, Quinn, John F., Davis, Thomas P., Halls, Michelle L, Quinn, John F, Boyd, Ben J, Davis, Thomas P, Ben J. Boyd, Whittaker, Michael R., Michael R. Whittaker, Ercole, Francesca, Thomas P. Davis   +16 more
core   +1 more source

The organosulfides diallyl sulfide, diallyl disulfide, and diallyl trisulfide accelerate benzo(a)pyrene metabolism in MCF‐10A cells

The FASEB Journal, 2012
Benzo(a)pyrene (BaP) is a naturally and anthropogenically produced carcinogen created during the incomplete combustion of organic material. BaP is considered a dietary, occupational, and environmental carcinogen, and BaP‐associated adducts have been found in the breast tissue and milk of women.
Candace C. Moyler, Yasmeen Nkrumah-Elie, William Dennis, Alicia Hudson, Rasha Hammamieh, Selina Darling-Reed   +5 more
openaire   +1 more source

Diallyl polysulfides from Allium sativum as immunomodulators, hepatoprotectors, and antimycobacterial agents [PDF]

, 2017
Mycobacterium tuberculosis remains one of the world's deadliest killers, with an annual death rate of ∼1.5 million. The medicinal effects of garlic have been well documented, and natural products have been shown to have antimycobacterial activity.
Oosthuizen, Carel, Hamilton, Chris, Lall, Namrita, Chris Hamilton, Carel Oosthuizen, Namrita Lall, Miriam Arbach, Oosthuizen, Carel Basson, Arbach, Miriam, Debra Meyer, Meyer, Debra   +10 more
core   +1 more source

Evaluating the Anti-Neuroinflammatory Capacity of Raw and Steamed Garlic as Well as Five Organosulfur Compounds

Molecules, 2014
The anti-neuroinflammatory capacities of raw and steamed garlic extracts as well as five organosulfur compounds (OSCs) were examined in lipopolysaccharide (LPS)-stimulated BV2 microglia.
Su-Chen Ho, Min-Sheng Su
doaj   +1 more source

Chemical Composition and Antimicrobial Activity of the Essential Oil from Consumed in Xishuangbanna, Southwest China

Natural Product Communications, 2014
The essential oil from the rhizomes of Allium hookeri Thwaites, obtained by simultaneous distillation extraction, was analyzed by GC-MS. Di-2-propenyl trisulfide (31.8%), diallyl disulfide (28.4%), and dipropyl trisulfide (8.4%) were the main ...
Ren Li, Yuan-Fei Wang, Qian Sun, Hua-Bin Hu   +3 more
doaj   +1 more source