Results 191 to 200 of about 12,487 (210)

Raman spectroscopic characteristics of diallyl trisulfide acting on trans‐crotonaldehyde

Journal of Raman Spectroscopy, 2015
In this paper, the molecular mechanism of diallyl trisulfide (DATS) on trans‐crotonaldehyde (TCA) was studied by UV–vis absorption and Raman spectroscopies combining with density functional theory calculations. Experimental results indicate that the introduction of DATS can not only make the maximum absorption peak of TCA shift 15 nm, but also ...
Yanbin Su, Lei Chen, Yingkun Cheng, Fengrong Zhang, Yanwen Su, Zhengqiang Li   +5 more
openaire   +1 more source

Diallyl trisulfide induces pyroptosis and impairs lung CSC-like properties by activating the ROS/Caspase 1 signaling pathway.

Chemico-Biological Interactions
Lung cancer stem cells (CSCs) drive continuous cancer growth and metastatic dissemination; thus, there is an urgent requirement to acquire effective therapeutic strategies for targeting lung CSCs.
Chun-feng Xie, Xu Zhou, Weiyi Chen, Dongxue Ren, Xiao-ting Li, Runqiu Jiang, Cai-yun Zhong, Jian-yun Zhu   +7 more
semanticscholar   +1 more source

Diallyl trisulfide regulates PGK1/Nrf2 expression and reduces inflammation to alleviate neurological damage in mice after traumatic brain injury.

Brain Research
BACKGROUND Diallyl trisulfide (DATS) has a direct antioxidant capacity and emerges as a promising neuroprotective agent. This study was designed to investigate the role of DATS in traumatic brain injury (TBI).
Yafei Chen, J.-L. Pang, Yulong Chen, Ying Liang, Zhengbo Zhang, Zhangquan Wang   +5 more
semanticscholar   +1 more source

Arsenic-induced hepatic mitochondrial toxicity in rats and its amelioration by diallyl trisulfide

Toxicology Mechanisms and Methods, 2013
The present investigation was aimed to investigate the possible protective role of diallyl trisulfide (DATS) against arsenic (As)-induced hepatic mitochondrial toxicity in rats. Mitochondria were isolated from the liver tissue of rats from all the groups.
S, Miltonprabu, N C, Sumedha
openaire   +2 more sources

Diallyl trisulfide alleviates dextran sulphate sodium‐induced colitis in mice by inhibiting NLRP3 inflammasome activation via ROS/Trx‐1 pathway

Basic & Clinical Pharmacology & Toxicology
Diallyl trisulfide (DATS), a sulphur‐containing compound isolated from the medicinal food plant garlic, has been previously reported to attenuate experimental colitis induced by either dextran sodium sulphate (DSS) or 2,4,6‐trinitrobenzenesulfonic acid ...
Yue He, Ling Xiao, Jing Zhang, Yanrong Zhu, Yi-zhen Guo, Yufeng Xia, Huatou Zhao, Zhifeng Wei, Yue Dai   +8 more
semanticscholar   +1 more source

Anticancer effects of diallyl trisulfide derived from garlic.

Asia Pacific journal of clinical nutrition, 2008
Alk(en)yl sulfides are characteristic flavor components of garlic. Several lines of epidemiological study indicate that the risk of a certain cancer can be prevented by consumption of garlic. In this manuscript, we examined the anticancer property of garlic-derived alk(en)yl sulfides, and the molecular basis especially for diallyl trisulfide which is a
Taiichiro, Seki, Takashi, Hosono, Tomomi, Hosono-Fukao, Kahoru, Inada, Rie, Tanaka, Jun, Ogihara, Toyohiko, Ariga   +6 more
openaire   +1 more source

Diallyl sulfide, diallyl disulfide and diallyl trisulfide affect drug resistant gene expression in colo 205 human colon cancer cells in vitro and in vivo

Phytomedicine, 2012
To elevate chemo-resistance of human cancer cells is a major obstacle in the treatment and management of malignant cancers. Diallyl sulfide (DAS), diallyl disulfide (DADS) and diallyl trisulfide (DATS) are presented in the Alliaceae family particularly in garlic.
Kuang-Chi, Lai, Chao-Lin, Kuo, Heng-Chien, Ho, Jai-Sing, Yang, Chia-Yu, Ma, Hsu-Feng, Lu, Hui-Ying, Huang, Fu-Shin, Chueh, Chien-Chih, Yu, Jing-Gung, Chung   +9 more
openaire   +2 more sources

Diallyl trisulfide and diallyl disulfide ameliorate cardiac dysfunction by suppressing apoptotic and enhancing survival pathways in experimental diabetic rats

Journal of Applied Physiology, 2013
Cardiovascular disease is one of the major causes of mortality in diabetic patients. Mounting studies have shown that garlic exhibits, possibly through its antioxidant potential, diverse biological activities. In this study, we investigated the alleviating effects of garlic oil (GO) and its two major components, diallyl disulfide (DADS) and diallyl ...
Yao-Te, Huang, Chun-Hsu, Yao, Chia-Li, Way, Kung-Wei, Lee, Cheng-Yen, Tsai, Hsiu-Chung, Ou, Wei-Wen, Kuo   +6 more
openaire   +2 more sources

Preparation and stability of diallyl trisulfide self-assembled micellar injection.

PDA journal of pharmaceutical science and technology, 2016
Diallyl trisulfide (DATS) has shown various biological activities, such as antimicrobial, antihyperlipidemic, antithrombotic, and anticancer effects. It is a highly water insoluble thioether compound, which irritates blood vessels and degrades rapidly under normal conditions.
Xiulan, Ju, Shixuan, Zhang, Qing, Wang, Xiaona, Li, Puwen, Yang   +4 more
openaire   +1 more source

Simultaneous determination of diallyl trisulfide and diallyl disulfide in rat blood by gas chromatography with electron-capture detection.

Die Pharmazie, 2007
A simple, rapid and sensitive method has been developed and validated for the simultaneous quantification of diallyl trisulfide (DATS) and diallyl disulfide (DADS) in rat blood by gas chromatography with electron-capture detection. The analytes were prevented from degradation by addition of acetonitrile and extraction with hexane before gas ...
X, Sun, T, Guo, J, He, M, Zhao, M, Yan, F, Cui, Y, Deng   +6 more
openaire   +1 more source