Results 171 to 180 of about 12,487 (210)

In vitro anti-synovial sarcoma effect of diallyl trisulfide and mRNA profiling

Gene, 2022
Synovial sarcoma (SS) is a malignant soft tissue sarcoma and its natural history is a long, indolent clinical course followed by high rate of local recurrence and distant metastasis. Current therapies are still limited in increasing satisfactory of 5-year survival, especially for patients with recurrence and metastasis.
Sheng-Li, Xia, Zi-Yuan, Ma, Bin, Wang, Feng, Gao, Cun-Guo, Yi, Xiao-Xiao, Zhou, Sheng-Yang, Guo, Li, Zhou   +7 more
openaire   +2 more sources

Degradation Urushiol Coating Composition Crosslinked by Diallyl Trisulfide

Journal of Polymers and the Environment, 2020
Urushiol (UR) was a kind of natural paint with a long history and excellent performance. Its high price restricts its development. For the sake of the sustainable development of UR, we prepared a new urushiol based coating composition which is of degradation.
Hanyu Xue, Yuchi Zhang, Xinzhong Li, Jianrong Xia, Qi Lin   +4 more
openaire   +1 more source

Diallyl trisulfide inhibits monosodium urate-induced NLRP3 inflammasome activation via NOX3/4-dependent mitochondrial oxidative stress in RAW 264.7 and bone marrow-derived macrophages.

Phytomedicine, 2023
BACKGROUND Monosodium urate (MSU) crystals are associated with gouty inflammatory diseases. MSU-associated inflammation is majorly triggered by NOD-like receptor protein 3 (NLRP3) inflammasome that promotes interleukin (IL)-1β secretion. Although diallyl
M. Kim, EunJin Bang, Hyun Hwangbo, S. Ji, D. Kim, Hyesook Lee, Cheol Park, S. Hong, Gi-Young Kim, Yung-Hyun Choi   +9 more
semanticscholar   +1 more source

Diallyl trisulfide inhibits 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung cancer via modulating gut microbiota and the PPARγ/NF-κB pathway.

Food & Function, 2023
Smoking is the primary risk factor for developing lung cancer. Chemoprevention could be a promising strategy to reduce the incidence and mortality rates of lung cancer.
Zhuo Qu, Jingwen Tian, Jiachen Sun, Ying Shi, Jian-Qiang Yu, Wannian Zhang, Chunlin Zhuang   +6 more
semanticscholar   +1 more source

Diallyl trisulfide ameliorates bone loss and alters specific gut microbiota and serum metabolites in natural aging mice.

Food & Function, 2023
Aging is a major cause of bone loss and osteoporosis. Diallyl trisulfide (DATS), one of the main organic sulfides in garlic oil, has been shown to alleviate arthritis in mice.
Feng Zhang, Jia Xu, Yanzhou Hu, Jingjing Fang, Minglan Yang, Kunlun Huang, Wentao Xu, Xiaoyun He   +7 more
semanticscholar   +1 more source

Diallyl Trisulfide, A Major Bioactive Constituent Of The Garlic, Promotes Colonic Mucosal Healing In Ulcerative Colitis Through Accelerating Focal Adhesion Assembly And Consequent Epithelial Cell Migration Via The Rab21-Integrin Β1-Fak Pathway.

Molecular Nutrition & Food Research, 2023
SCOPE Colonic mucosal healing is the terminal goal for the treatment of ulcerative colitis (UC), but there is currently no specific drug available. This study investigated the beneficial effect of diallyl trisulfide (DATS) on the colonic mucosal healing.
Yajing Zhang, Yi-zhen Guo, Qin Zhang, Yanrong Zhu, Yufeng Xia, Zhifeng Wei, Yue Dai   +6 more
semanticscholar   +1 more source

Diallyl trisulfide inhibits gastric cancer stem cell properties through ΔNp63/sonic hedgehog pathway

Molecular Carcinogenesis, 2023
Gastric cancer is one of the deadliest malignant tumors, and half of the patients develop recurrences or metastasis within 5 years after eradication therapy. Cancer stem cells (CSCs) are considered to be important in this progress.
Miaomiao Ge, Jian-yun Zhu, Kefan Yi, Yue Chen, Wanshuang Cao, Meng-huan Wang, Chun-feng Xie, Xiao-ting Li, Shan-shan Geng, Jie-shu Wu, Cai-yun Zhong, H. Cao, Zhiwei Jiang, Hong-yu Han   +13 more
semanticscholar   +1 more source

Diallyl trisulfide and its active metabolite allyl methyl sulfone attenuate cisplatin-induced nephrotoxicity by inhibiting the ROS/MAPK/NF-κB pathway.

International Immunopharmacology, 2023
Cisplatin, a chemotherapy medication employed in the treatment of various solid tumors, is constrained in its clinical application due to nephrotoxicity.
Xiaoyan Jiang, Xiaosong Zhu, Yan Liu, Nan Zhou, Zhongxi Zhao, Huaiyou Lv   +5 more
semanticscholar   +1 more source

Diallyl trisulfide ameliorates arsenic induced dyslipidemia in rats

Food Science and Biotechnology, 2015
The efficacy of diallyl trisulfide (DATS) against arsenic (As) induced dyslipidemia in the plasma and livers of rats was studied.
Selvaraj Miltonprabu, Naorem Chanu Sumedha   +1 more
openaire   +1 more source

Diallyl Trisulfide Suppresses Tumor‐Associated Macrophage M2‐Like Polarization and Recruitment and Improves the Tumor Microenvironment Through Blocking CCL5/STAT3 Signaling Pathway Against Lung Cancer

Phytotherapy Research
Diallyl trisulfide (DATS) is a promising small molecule phytochemical derived from allium vegetables with antitumor potential. Tumor‐associated macrophages (TAMs) are the most abundant tumor‐infiltrating immune cells within the lung tumor ...
Chun-feng Xie, Juan Yin, Jianyun Zhu
semanticscholar   +1 more source