Results 161 to 170 of about 4,781 (281)

Sustainable recovery of a chitin–glucan complex–protein biocomposite from yeast biomass using biocompatible ionic liquids

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract Chitin–glucan complex (CGC) is typically extracted from fungal or yeast biomass using harsh alkaline treatments that not only generate high‐salt, organic‐rich effluents, but also negatively impact the structural and functional properties of the recovered copolymer, while wasting the yeast protein fraction, which is discarded.
Inês C. Ferreira   +4 more
wiley   +1 more source

Safety and pharmacokinetics of a novel potent GABA analogue crisugabalin in Chinese subjects with various degrees of renal impairment

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Crisugabalin is a novel calcium channel α2δ subunit ligand and a highly selective oral gamma‐aminobutyric acid (GABA) analogue developed for the treatment of diabetic peripheral neuropathic pain (DPNP) and postherpetic neuralgia (PHN). This study investigated pharmacokinetic properties and safety of crisugabalin in subjects with renal impairment ...
Shibeilei Lin   +6 more
wiley   +1 more source

[Psychological impact of lockdown and the COVID-19 epidemic on haemodialysis patients and carers in France]. [PDF]

open access: yesNephrol Ther, 2021
Guerraoui A   +24 more
europepmc   +1 more source

Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel   +12 more
wiley   +1 more source

Hydrogel Embedding of Mesenchymal Stem Cells Supports Extracellular Vesicle Production

open access: yesBiotechnology and Bioengineering, EarlyView.
This study investigates the effects of 3D culture conditions on extracellular vesicle (EV) production by mesenchymal stem cells (MSCs) in a gelatin‐based hydrogel matrix (GelMA). The EVs from both conditions were found to have similar morphological, molecular, and functional properties, but 3D cultures produced more total EVs per volume.
Rachel K. Moen   +5 more
wiley   +1 more source

Home Sweet Home: A Program Report on Promoting the Uptake of Home Dialysis. [PDF]

open access: yesCan J Kidney Health Dis
Churchill LJ   +4 more
europepmc   +1 more source

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