Multiple acquired portosystemic shunts in a cat secondary to chronic diaphragmatic rupture [PDF]
A cat with a chronic diaphragmatic rupture presented with neurological signs, including twitching and focal seizures. Blood ammonia level was markedly elevated and therefore neurological signs were thought to be related to hepatic encephalopathy ...
Birchard SJ +3 more
core +3 more sources
Diaphragm dysfunction induced by mechanical ventilation – pathophysiology and treatment options [PDF]
Majority of mechanically ventilated patients in intensive care units (ICU) suffer from diaphragm dysfunction. It occurs in approximately 60 to 80 % of such patients.
Iva Pažur +2 more
doaj +1 more source
Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment [PDF]
Duchenne muscular dystrophy (DMD) is caused by loss of dystrophin protein, leading to progressive muscle weakness and premature death due to respiratory and/or cardiac complications.
Ball, V +15 more
core +3 more sources
Ventilator-induced diaphragm dysfunction in critical illness [PDF]
Mechanical ventilation is an essential intervention for intensive care unit patients with acute lung injury. However, the use of controlled mechanical ventilation in both animal and human models causes ventilator-induced diaphragm dysfunction, wherein a substantial reduction in diaphragmatic force-generating capacity occurs, along with structural ...
Yung-Yang, Liu, Li-Fu, Li
openaire +2 more sources
Background: Although muscle dysfunction is a major contributor to morbidity in chronic obstructive pulmonary disease (COPD), assessment of skeletal muscle, and diaphragm function is not routinely performed in COPD patients.Objectives: (1) The aim is to ...
Priya Ramachandran +7 more
doaj +1 more source
Diaphragm Dysfunction (Paralysis) in a Cystic Fibrosis Patient [PDF]
Diaphragmatic Paralysis (DP) is a rare disease and usually occurs secondary to systemic processes, although idiopathic forms have been described. Management of diaphragmatic paralysis depends on multiple factors, including the etiology, presence, or absence of symptoms, and more importantly, the presence of nocturnal hypoventilation.
Muhammad Zubair Khan +3 more
openaire +2 more sources
Early changes in rat diaphragm biology with mechanical ventilation [PDF]
To better characterize the effects of 24-hour mechanical ventilation on diaphragm, the expression of myogenic transcription factors, myosin heavy chains, and sarcoplasmic/endoplasmic reticulum calcium-ATPase pumps was examined in rats.
Cadot, Pascal +7 more
core +1 more source
Diaphragm dysfunction: weaning perspective
Weaning is the process of successfully liberating the patient from mechanical ventilation. The majority of patients will separate from the ventilator after a successful spontaneous breathing trial (SBT). In a minority of patients, weaning can be challenging and prolonged.
openaire +1 more source
Ventilator-induced diaphragm dysfunction: cause and effect [PDF]
Mechanical ventilation (MV) is used clinically to maintain gas exchange in patients that require assistance in maintaining adequate alveolar ventilation. Common indications for MV include respiratory failure, heart failure, drug overdose, and surgery.
Scott K, Powers +3 more
openaire +2 more sources
Diaphragmatic thickening fraction as a predictor for intubation in patients with COVID-19
The diaphragm is the primary respiratory muscle, and its dysfunction predisposes patients to respiratory failure. Diaphragm function can be assessed by ultrasound measurement - Diaphragmatic Thickening Fraction (DTF).
Manuel Hache-Marliere +2 more
doaj +1 more source

