Results 51 to 60 of about 20,082 (208)

Different Types of Vaccines against Pestiviral Infections: “Barriers” for “Pestis”

Viruses, 2022
The genus Pestivirus of the family Flaviviridae mainly comprises classical swine fever virus (CSFV), bovine viral diarrhea virus 1 (BVDV-1), BVDV-2, border disease virus (BDV), and multiple new pestivirus species such as atypical porcine pestivirus (APPV)
Mengqi Yuan, Xiaoke Yang, Xin Zhang, Xiaotian Zhao, Muhammad Abid, Hua-Ji Qiu, Yongfeng Li   +6 more
doaj   +1 more source

Structural Polymorphism of polyG Inclusions Revealed by In Situ Cryo‐Electron Tomography

Advanced Science, EarlyView.
Correlative cryo‐electron tomography in primary cortical neurons and NIID mouse brain tissue reveals that polyG inclusions are interconnected ribbon‐like assemblies rather than canonical amyloid fibrils. Multiple compartment‐specific ribbon states show distinct 26S proteasome accessibility, while cytoplasmic ribbons contact and deform ER‐like ...
Yunwen Qian, Yalan Wan, Chen Chen, Xiaoyu Zheng, Wenjing Du, Junhan Yang, Zhihao Quan, Biyu Yang, Jiaxi Yu, Jie Zheng, Zhaoxia Wang, Jianwen Deng, Qiang Guo   +12 more
wiley   +1 more source

Detection of bovine viral diarrhea-mucosal disease (BVD-MD) virus in Dromedary camel in Iraq using ELISA/ A preliminary study [PDF]

Mirror of Research in Veterinary Sciences and Animals, 2016
Bovine Viral Diarrhea- Mucosal Disease (BVD- MD) virus causes a high economic losses. BVD-MD infects a wide range of domestic animals (cattle, buffaloes, sheep and goat).
Khawlah Moh Imran Al-Rubayie
doaj  

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

Advanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon, Seo‐Hyeon Bae, Jungyong Ji, Jisun Lee, Hosam Choi, Min‐Ho Kang, Sang‐In Park, Hyemin Kim, Nakyung Lee, Hajin Lee, Seonghoon Kim, Jungmin Kim, Subin Yoon, Seonghyun Lee, Seongje Cho, Dahyeon Ha, Ayoung Oh, Sohee Jo, Huijeong Choi, Yeeun Lee, Sowon Lee, Hyo‐Jung Park, Gitak Nam, Jisu Shin, Yujin Kang, Wonpil Im, Kiyoun Lee, Jae‐Hwan Nam   +27 more
wiley   +1 more source

Antigenic relationships between Bovine viral diarrhea virus 1 and 2 and HoBi virus [PDF]

Journal of Veterinary Diagnostic Investigation, 2012
The emergence of a newly recognized group of pestiviruses in cattle, the HoBi-like viruses, requires an evaluation of the available diagnostic tools and vaccines. The present study compared antigenic characteristics of Bovine viral diarrhea virus 1 and 2 (BVDV-1, -2) strains and HoBi virus. This comparison was based on detection of
Fernando V, Bauermann, Eduardo F, Flores, Julia F, Ridpath   +2 more
openaire   +2 more sources

Involvement of the Wnt pathway in BVDV cytopathogenic strain replication in primary bovine cells

Virology Journal, 2022
Background Bovine viral diarrhea virus 1 (BVDV-1) of the pestivirus genus is an economically crippling virus in the cattle industry; this positive RNA virus causes mucosal disease resulting in reproductive losses and other disease syndromes.
Rémi La Polla, Marie-Claire Testard, Océane Garcia, Abdelghafar Goumaidi, Catherine Legras-Lachuer, Blandine de Saint-Vis   +5 more
doaj   +1 more source

SPSB1 Promotes Subcutaneous Adipose Hyperplasia in Facial Port‐Wine Stains by Controlling HDAC1 Degradation and Stability Through Two Distinct Proteolytic Pathways

Advanced Science, EarlyView.
In PWS‐ASPCs, FOSL1 drives the expression of SPSB1. SPSB1, as part of the ESC complex, further binds to HDAC1 and promotes K29‐linked and K48‐linked polyubiquitination of HDAC1. These modifications facilitate the degradation of HDAC1 through the ALP and UPS pathways, respectively.
Hongrui Chen, Bin Sun, Yajing Qiu, Chen Hua, Xiaoxi Lin, Wei Gao   +5 more
wiley   +1 more source

The Influence of the Associated Inactivated Vaccine Against Infectious Rhinotracheitis and Bovine Viral Diarrhea on the Formation and Duration of Colostral Immunity in Kazakh Whiteheaded Calves

Vaccines
Objectives: This article presents a study evaluating the antibody levels against infectious bovine rhinotracheitis (IBR) and bovine viral diarrhea (BVD) in Kazakh Whiteheaded calves born to dams immunized with an experimental inactivated combined vaccine
Yerbol Bulatov, Alina Kurmasheva, Zhanat Amanova, Ruslan Abitaev, Zhanna Sametova, Asselya Kyrgyzbayeva, Zhanat Kondybaeva, Sholpan Turyskeldi, Abdurakhman Ussembay, Dariya Toktyrova, Dana Mazbayeva, Yeraly Shayakhmetov, Aslan Kerimbayev, Damir Khussainov, Ma Wentao, Aralbek Rsaliyev, Yergali Abduraimov   +16 more
doaj   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

Advanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie, Yanbo Zhu, Wenhua Jiang, Haobo Xie, Yaojia Li, Mengjie Hu, Kezheng Li, Huan Yu, Yixuan Pan, Chaoyi Jiang, Xueqin Song, Dongsheng Fan, Binbin Deng   +12 more
wiley   +1 more source

Outbreaks of pneumonia in beef calves associated with bovine viral diarrhea virus seroconversion and other respiratory pathogens

Journal of Veterinary Medical Research, 2005
The present study describes the clinical, serological and bacteriolological findings in calves from two beef herds experiencing outbreaks of pneumonia. The clinical signs were nasal discharge, cough, pyrexia and increased respiratory rates.
A. M. Khadr
doaj