Results 61 to 70 of about 19,492 (198)

NET‐DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy‐Mediated Anoikis Resistance in Endometriosis

Advanced Science, EarlyView.
NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang, Yanling Gou, Huiyan Zhang, Hongli Wang, Beidi Wang, Jinming Liu, Yingying Cao, Ruru Bai, Yuxin Zhao, Xu Han, Chao Feng, Xin Huang, Zongfeng Zhang   +12 more
wiley   +1 more source

Real Time Analysis of Bovine Viral Diarrhea Virus (BVDV) Infection and Its Dependence on Bovine CD46

Viruses, 2020
Virus attachment and entry is a complex interplay of viral and cellular interaction partners. Employing bovine viral diarrhea virus (BVDV) encoding an mCherry-E2 fusion protein (BVDVE2-mCherry), being the first genetically labelled member of the family ...
Christiane Riedel, Hann-Wei Chen, Ursula Reichart, Benjamin Lamp, Vibor Laketa, Till Rümenapf   +5 more
doaj   +1 more source

No effects of noncytopathic bovine viral diarrhea virus type 2 on the reproductive tract of experimentally inoculated boars

Veterinary Microbiology, 2020
Bovine viral diarrhea virus (BVDV) infections in pigs may result in transient leukopenia, chronic gastroenteritis, septicemia, and hemorrhagic lesions. Both classical swine fever virus (CSF) and the atypical porcine pestivirus (APPV) are shed in the semen of infected boars. Because these viruses share conserved regions and present antigenic similarity,
Storino, Gabriel Yuri, Xavier, Eduarda Bellini, Mechler-Dreibi, Marina Lopes, Simonatto, Artur, Gatto, Igor Renan Honorato, Oliveira, Maria Emilia Franco, Pituco, Edviges Maristela, de Oliveira, Luís Guilherme   +7 more
openaire   +4 more sources

Comparative virology and pathology of Monkeypox virus in Syrian hamsters, C57BL/6, and BALB/c mice: A framework for preclinical model selection

Animal Models and Experimental Medicine, EarlyView.
This study compared monkeypox virus (MPXV) infection in three small animal models: Syrian hamsters, C57BL/6 mice, and BALB/c mice. Following intraperitoneal inoculation, Syrian hamsters exhibited the highest susceptibility, with rapid systemic viral dissemination, elevated splenic and renal viral burdens, and severe histopathological damage, followed ...
Xiaohui Wei, Jing Wu, Hekai Yang, Na Li, Binbin Zhao, Wanjun Peng, Na Rong, Wei Zhang, Jing Xue, Jiangning Liu   +9 more
wiley   +1 more source

Outbreaks of pneumonia in beef calves associated with bovine viral diarrhea virus seroconversion and other respiratory pathogens

Journal of Veterinary Medical Research, 2005
The present study describes the clinical, serological and bacteriolological findings in calves from two beef herds experiencing outbreaks of pneumonia. The clinical signs were nasal discharge, cough, pyrexia and increased respiratory rates.
A. M. Khadr
doaj  

Heat Shock Protein 70 in Cold-Stressed Farm Animals: Implications for Viral Disease Seasonality

Microorganisms
The seasonal patterns of viral diseases in farm animals present significant challenges to global livestock productivity, with cold stress emerging as a potential modulator of host–pathogen interactions.
Fanzhi Kong, Xinyue Zhang, Qi Xiao, Huilin Jia, Tengfei Jiang   +4 more
doaj   +1 more source

Cattle connection: molecular epidemiology of BVDV outbreaks via rapid nanopore whole-genome sequencing of clinical samples

BMC Veterinary Research, 2021
Background As a global ruminant pathogen, bovine viral diarrhea virus (BVDV) is responsible for the disease Bovine Viral Diarrhea with a variety of clinical presentations and severe economic losses worldwide.
Jacqueline King, Anne Pohlmann, Kamila Dziadek, Martin Beer, Kerstin Wernike   +4 more
doaj   +1 more source

Virulence Markers in the 5′ Untranslated Region of Genotype 2 Bovine Viral Diarrhea Virus Isolates

Virology, 1998
Virulence markers to distinguish high from low virulence bovine viral diarrhea virus genotype 2 isolates have not been previously reported. The objective of this study was to identify virulence markers by evaluating the primary and secondary structures of the 5'-untranslated region of low and high virulence bovine viral diarrhea virus genotype 2 ...
Topliff, Christina L, Kelling, Clayton L
openaire   +2 more sources

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

Advanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham, Karthikeya S. V. Gottimukkala, Daniel D. Lane, Katrina Poljakov, Patricia Lipson, Mark R. Enstrom, Alessandro Rizzi, Aude G. Chapuis, Jennifer E. Adair   +8 more
wiley   +1 more source

Additional file 2 of Molecular detection and genotyping of bovine viral diarrhea virus in Western China

, 2021
Additional file 2.
Lingling Chang (350993), Yanping Qi (5549528), Dan Liu (108669), Qian Du (280345), Xiaomin Zhao (566041), Dewen Tong (93139)   +5 more
openaire   +2 more sources