Results 71 to 80 of about 19,492 (198)

A Rare RIPK3 Variant Enhances Necroptosis and Promotes Inflammation in a Still Disease–Like Autoinflammatory Syndrome

Arthritis &Rheumatology, EarlyView.
Objective Still disease represents a prototypical polygenic systemic autoinflammatory disease, characterized by recurrent systemic inflammation and dysregulation of innate immunity. Despite extensive clinical characterization, familial clustering Still disease remains unreported.
Longfang Chen, Qihua Dai, Yu Xiao, Jialin Dai, Mengyan Wang, Yuning Ma, Yujie Shen, Zhimo Xu, Jianfen Meng, Xia Chen, Da Yi, Yue Sun, Hui Shi, Honglei Liu, Xiaobing Cheng, Yutong Su, Junna Ye, Huihui Chi, Zhuochao Zhou, Tingting Liu, Jialin Teng, Chengde Yang, Jinchao Jia, Qiongyi Hu   +23 more
wiley   +1 more source

Design Space Assessment of Virus Inactivation in Plasma‐Derived Matrices Establishes a Single Detergent Alternative to TX‐100‐Containing Mixes

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The detergent Triton X‐100 (TX‐100) is a typical component of solvent/detergent (S/D) mixes applied for virus inactivation steps of biomanufacturing processes, yet environmentally unfavorable properties have led to restrictions on its use. Deviron 13‐S9 has recently been described as an eco‐friendly TX‐100 alternative, with powerful virus ...
Johanna Kindermann, Cecilie Klausen, Michael Karbiener, Thomas R. Kreil   +3 more
wiley   +1 more source

Berberine alleviates cell pyroptosis in diabetic retinopathy by regulating AKT1, JUN, and STAT3

Ibrain, EarlyView.
Berberine alleviates diabetic retinopathy by reducing pyroptosis through AKT1/JUN/STAT3 regulation, as validated in rat models via network pharmacology, molecular docking, and experimental assays. Abstract Berberine (BBR) exerts an effective protection for diabetic retinopathy (DR), but the underlying key molecular mechanism remains unknown; this study
Na Li, Ji‐Lin Chen, Yi‐Jian Sun, Jia‐Fan Sun, Fatin Athirah Pauzi, Song‐Lin Zhu, Amy Yi Hsan Saik, Alan Han‐Kiat Ong   +7 more
wiley   +1 more source

Bacterial and viral agents in cattle with and without respiratory signs in dairy herds from São Paulo and Rio Grande do Sul states, Brazil [PDF]

Pesquisa Veterinária Brasileira
: Bovine respiratory disease is a multifactorial syndrome of complex etiology, involving interactions among bacterial and viral agents, and has a significant impact on the cattle industry worldwide.
Natália H. Pedroso, Iasmim F. Dionisio, Nathalia Roberta D. dos Santos, José Valter J. Silva Júnior, Chester P. Batista, Nathália Decaris, Viviani Gomes, Rudi Weiblen, Eduardo F. Flores   +8 more
doaj   +2 more sources

Clinical response and immunomodulation following experimental challenge of calves with type 2 noncytopathogenic bovine viral diarrhea virus [PDF]

Veterinary Research, 2000
Eight calves between 16 and 18 weeks of age that were seronegative to bovine viral diarrhea virus (BVDV), bovine leucosis virus and bovine immunodeficiency-like virus were infected (day 0) intranasally with the type 2 noncytopathogenic Canadian 24515 field isolate of BVDV in order to evaluate the effect of BVDV infection on certain clinical ...
Archambault, Denis, Béliveau, Christian, Couture, Yvon, Carman, Susy   +3 more
openaire   +2 more sources

Botanical treatment enhances biochemical responses in enset (Ensete ventricosum (Welw.) Cheesman) clones

JSFA reports, EarlyView.
Abstract Background Bacterial wilt of enset (Ensete ventricosum (Welw.) Cheesman) is a severe disease caused by Xanthomonas campestris pv. musacearum, resulting in complete crop failure and considerable damage. This study assessed the biochemical responses of two enset clones (one resistant and one susceptible) when inoculated with the pathogen and ...
Getahun Yemata, Masresha Fetene
wiley   +1 more source

Wafer‐Scale Deterministic Fabrication of Axis‐Ratio–Engineered Silicon Nanoparticles for On‐Resonance Electric–Magnetic Dipole Interference

Small, EarlyView.
Wafer‐scale top‐down fabrication yields silicon nanoparticles with exceptional uniformity (CV 1.7%–2.4%), enabling deterministic axis‐ratio tuning. At AR ≈$\approx$ 2.1, electric–magnetic dipoles overlap on‐resonance, producing near‐Kerker forward scattering (F/B ≈$\approx$ 12.5).
Taeyeong Kim, Jungchul Lee
wiley   +1 more source

Effect of Immunization with Two-Step Vaccine Program for Bovine Viral Diarrhea Virus 2

Journal of the Japan Veterinary Medical Association, 2011
SUMMARY We investigated the effects of immunization against bovine viral diarrhea virus (BVDV)h2 with a two-step vaccination program using attenuated live BVDV1 after immunizing by inactivated BVDV1 and BVDV2 vaccine. Fifteen calves that had taken adequate colostrum from a dairy farm in the Nemuro District of Hokkaido, Japan, were used. The calves were
Hajime KATO, Yukiko EMURA, Yoichi SAWAMUKAI, Yohei SATO, Eimitsu NISHIMATSU, Reiichiro SATO, Mamoru OONISHI, Motoshi TAJIMA   +7 more
openaire   +2 more sources

Reusing health records from farm animal practices at scale: A potential complementary method of surveillance

Veterinary Record, EarlyView.
Abstract Background Disease in primary care frequently represents a surveillance blind spot, particularly for diseases affecting farm animals. Methods Electronic health records (EHRs) were collected from four farm animal veterinary practices in Wales (February 2024‒January 2025) as part of a pilot study.
Beverley Hopkins, Peers Davies, Peter‐John Noble, Anna Bunford‐Davies, April Lawson, Gina Pinchbeck, Ifan Lloyd, Robert Smith, Alan D. Radford   +8 more
wiley   +1 more source

A CRISPR/Cas9 Generated Bovine CD46-knockout Cell Line—A Tool to Elucidate the Adaptability of Bovine Viral Diarrhea Viruses (BVDV)

Viruses, 2020
Bovine viral diarrhea virus (BVDV) entry into a host cell is mediated by the interaction of the viral glycoprotein E2 with the cellular transmembrane CD46 receptor.
Kevin P. Szillat, Susanne Koethe, Kerstin Wernike, Dirk Höper, Martin Beer   +4 more
doaj   +1 more source