Results 141 to 150 of about 41,873 (277)

Nanomedicine for Oral Delivery: Strategies to Overcome the Biological Barriers

Small Methods, EarlyView.
Oral delivery is a preferred administration route for many clinical applications, valued for its strong patient compliance. In this review, how nanoparticles are engineered and deployed to overcome the gastrointestinal barriers that impede clinical translation of oral delivery formulations is examined.
Luke J. Kubiatowicz, Nima Pourafzal, Audrey T. Zhu, Zhongyuan Guo, Ronnie H. Fang, Liangfang Zhang   +5 more
wiley   +1 more source

Immunological response of locally prepared oil adjuvanted pneumo-5 vaccine in calves

Journal of Veterinary Medical Research, 2017
he present study aimed to prepare a combined inactivated vaccine containing bovine viral diarrhea genotype-1(BVD-1),bovine viral diarrhea genotype-2 (BVD-2), infectious bovine rhinotracheitis (IBR),parainfluenza-3 (PI-3) and bovine respiratory syncytial ...
Rasha,I.EL-Hawary, Hanaa A. Mostafa
doaj  

RAA-CRISPR/Cas12a-based visual field detection system for rapid and sensitive diagnosis of major viral pathogens in calf diarrhea

Frontiers in Cellular and Infection Microbiology
Calf diarrhea is a complex digestive disorder in cattle that imposes significant economic losses in terms of calf mortality, growth impairment, and treatment costs.
Junzhen Chen, Junzhen Chen, Yu Wang, Yu Wang, Rezeguli Aikebaier, Rezeguli Aikebaier, Haoran Liu, Yingxin Li, Yingxin Li, Li Yang, Li Yang, Areayi Haiyilati, Areayi Haiyilati, Lixia Wang, Lixia Wang, Qiang Fu, Qiang Fu, Huijun Shi, Huijun Shi   +18 more
doaj   +1 more source

Descriptive analysis of national bovine viral diarrhoea test data in England (2016–2023)

Veterinary Record, EarlyView.
Abstract Background Bovine viral diarrhoea (BVD) is an endemic disease in the UK. In England, a voluntary control and eradication scheme, BVDFree England, has been running since 2016. Methods We analysed test results from 7005 herds that were submitted to BVDFree England between 2016 and 2023 to investigate changes in the prevalence of BVD in ...
Naomi S. Prosser, Edward M. Hill, Lorna Gow, Massimo Cavallaro, Michael J. Tildesley, Matt J. Keeling, Jasmeet Kaler, Eamonn Ferguson, Martin J. Green   +8 more
wiley   +1 more source

Nanotechnology and cell death: Revolutionizing disease treatment with nanoparticle strategies

VIEW, EarlyView.
Traditional disease treatments often face issues such as poor drug targeting and significant side effects, with many complex diseases lacking effective therapies. Our research utilizes tiny nanomaterials to treat diseases by regulating natural cell death processes, improving the immune environment, etc., enabling drugs to act more precisely.
Yiwen Wan, Wangzheqi Zhang, Yan Liao, Chenglong Zhu, Xiaojing Guo, Zui Zou, Mi Li   +6 more
wiley   +1 more source

Chronic Cellular NAD Depletion Activates a Viral Infection‐Like Interferon Response Through Mitochondrial DNA Leakage

Aging Cell, EarlyView.
Chronic NAD depletion in fibroblasts lowers NAD levels, increases mitochondrial mass, and triggers an interferon‐dependent inflammatory response via mtDNA leakage through VDAC1, activating the cGAS‐STING pathway. This links NAD deficiency to metabolic and inflammatory processes, with implications for diseases associated with NAD decline.
Claudia C. S. Chini, Laura Colman, Eduardo Palmieri, Jessica L. Strange, Sonu Kashyap, Bing Han, Andres Benitez‐Rosendo, Gina L. Ciccio Lopez, Sara Peixoto Rabelo, Shreyartha Mukherjee, Gustavo H. de Souza, John Varga, Ralph G. Meyer, Mirella L. Meyer‐Ficca, Eduardo N. Chini   +14 more
wiley   +1 more source

Role of assisted reproduction biotechniques in the transmission of bovine viral diarrhea virus [PDF]

, 2015
Las biotécnicas de reproducción asistida han adquirido importancia comercial en los últimos años. Asociado a estas técnicas surge el interrogante sobre su rol en la posible transmisión de agentes infecciosos vía semen y ovocitos utilizados como material ...
Gonzalez Altamiranda, Erika Analia, Kaiser, Germán Gustavo, Odeón, Anselmo Carlos   +2 more
core   +1 more source

Single‐dose Pasteurella multocida and Histophilus somni autogenous vaccines administered at induction significantly improved feedlot cattle performance and profitability in Australia

Australian Veterinary Journal, EarlyView.
Background Bovine respiratory disease (BRD) is the most economically important disease affecting feedlot cattle. While viral pathogens are initiating agents, bacterial coinfections exacerbate disease severity. Vaccines for Pasteurella multocida and Histophilus somni are not commercially available in Australia.
GM Werid, T Batterham, L O'Meara, K Petrovski, WS Pitchford, DJ Trott   +5 more
wiley   +1 more source

Radiographic Peri‐Implant Bone Changes in Osteoporotic Women Treated With a Ti‐Zr, Bone Level Tapered Implant With a Hydrophilic Surface: A 12‐Month Prospective Case‐Series

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives This study assessed 12‐month post‐loading 3D peri‐implant radiographic bone changes in osteoporotic women receiving a single titanium‐zirconium bone‐level tapered dental implant with a hydrophilic surface. Materials and Methods This was a prospective case series involving 18 post‐menopausal osteoporotic women in need of a single ...
Calciolari Elena, Mardas Nikos, Palaska Iro, Tagliaferri Sara, Donos Nikolaos   +4 more
wiley   +1 more source

Super‐Enhancer Target Gene CBP/p300‐Interacting Transactivator With Glu/Asp‐Rich C‐Terminal Domain, 2 Cooperates With Transcription Factor Forkhead Box J3 to Inhibit Pulmonary Vascular Remodeling

Cell Proliferation, EarlyView.
During hypoxia, the transcriptional effect of super‐enhancer in promoting CBP/p300‐interacting transactivator with Glu/Asp‐rich C‐terminal domain, 2 reduced, eventually leading to the thickening of the smooth muscle layer of the pulmonary artery.
Songyue Li, Jingya Zhang, Xu Wang, Xinru Wang, Yuyu Song, Xinyue Song, Xiuli Wang, Weiwei Cao, Chong Zhao, Jing Qi, Xiaodong Zheng, Yan Xing   +11 more
wiley   +1 more source