Results 131 to 140 of about 1,031,287 (257)

Immune Consequences of Metabolic Syndrome and Its Treatment: A Cytokine Perspective

Immunology, Volume 179, Issue 3, Page 390-405, November 2026.
Peripheral blood mononuclear cells (PBMCs) from individuals with metabolic syndrome (MetS) who were not using glucose‐and/or lipid lowering medication (GLLM) exhibited a broader cytokine production profile after in vitro antigen‐specific stimulation than PBMCs from individuals with MetS using such medications and from healthy donors.
Isabela Ghetti Macedo Isaac, Carolina do Prado Servian, Fernanda de Oliveira Feitosa de Castro, João Lucas Lima Calandrini de Azevedo, Ronaldo Moraes Preto, Miriam Leandro Dorta, Daniela Espíndola Antunes, Simone Gonçalves Fonseca   +7 more
wiley   +1 more source

Structural Polymorphism of polyG Inclusions Revealed by In Situ Cryo‐Electron Tomography

Advanced Science, Volume 13, Issue 56, 9 October 2026.
Correlative cryo‐electron tomography in primary cortical neurons and NIID mouse brain tissue reveals that polyG inclusions are interconnected ribbon‐like assemblies rather than canonical amyloid fibrils. Multiple compartment‐specific ribbon states show distinct 26S proteasome accessibility, while cytoplasmic ribbons contact and deform ER‐like ...
Yunwen Qian, Yalan Wan, Chen Chen, Xiaoyu Zheng, Wenjing Du, Junhan Yang, Zhihao Quan, Biyu Yang, Jiaxi Yu, Jie Zheng, Zhaoxia Wang, Jianwen Deng, Qiang Guo   +12 more
wiley   +1 more source

Experimental infection of pregnant sheep with bovine viral diarrhea virus 1b (AU526)

, 2015
Bovine viral diarrhea virus (BVDV) lacks strict host specificity and can infect many species in the order Artiodactyla. BVDV infection in pregnant heterologous hosts can be deleterious.
Passler, T., Riddell, K. P., Newcomer, B. W., Walz, P. H., Kuca, T., Neill, J. D.   +5 more
core   +1 more source

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2289-2308, October 2026.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu, Rosan Kenana, Rana Chakrabarti, Sarah D. P. Wilhelm, Joseph Andrews, Susan J. Leat, Christina Parker, Michael Miller, Leslie A. Nangle, Wendy McCaul, Ashfia Chowdhury, Natalie Hutchings, Ryan A. Adams, Lauren Guy, Mandy Rhody, Verena Juncal, Marisa I. Mendes, Desiree E. C. Smith, Gajja S. Salomons, Angelica A. Moresco, Daphne L. McCulloch, D. Holmes Morton, Ilka U. Heinemann, C. Anthony Rupar   +23 more
wiley   +1 more source

Variation in Viremic Concentration among Cattle Persistently Infected with Bovine Viral Diarrhea Virus

, 2009
Cattle persistently infected (Pl) with bovine viral diarrhea virus (BVDV) are the main viral reservoir of the disease. Despite associations between BVDV and negative health and performance effects, previous research suggests that PI cattle have minimal ...
Nickell, J. S., Renter, D. R., Larson, R. L ., White, B. J.   +3 more
core   +1 more source

Molecular characterization of positive-stranded RNA viruses [PDF]

, 1993
Rümenapf, T., Unger, G., Thiel, Heinz-Jürgen, Kaaden, Oskar-Rüger, Meyers, G., Stark, R., Conzelmann, Karl-Klaus, Tautz, N.   +7 more
core   +1 more source

RAA-CRISPR/Cas12a-based visual field detection system for rapid and sensitive diagnosis of major viral pathogens in calf diarrhea

Frontiers in Cellular and Infection Microbiology
Calf diarrhea is a complex digestive disorder in cattle that imposes significant economic losses in terms of calf mortality, growth impairment, and treatment costs.
Junzhen Chen, Junzhen Chen, Yu Wang, Yu Wang, Rezeguli Aikebaier, Rezeguli Aikebaier, Haoran Liu, Yingxin Li, Yingxin Li, Li Yang, Li Yang, Areayi Haiyilati, Areayi Haiyilati, Lixia Wang, Lixia Wang, Qiang Fu, Qiang Fu, Huijun Shi, Huijun Shi   +18 more
doaj   +1 more source

A Rare RIPK3 Variant Enhances Necroptosis and Promotes Inflammation in a Still Disease–Like Autoinflammatory Syndrome

Arthritis &Rheumatology, Volume 78, Issue 10, Page 2149-2159, October 2026.
Objective Still disease represents a prototypical polygenic systemic autoinflammatory disease, characterized by recurrent systemic inflammation and dysregulation of innate immunity. Despite extensive clinical characterization, familial clustering Still disease remains unreported.
Longfang Chen, Qihua Dai, Yu Xiao, Jialin Dai, Mengyan Wang, Yuning Ma, Yujie Shen, Zhimo Xu, Jianfen Meng, Xia Chen, Da Yi, Yue Sun, Hui Shi, Honglei Liu, Xiaobing Cheng, Yutong Su, Junna Ye, Huihui Chi, Zhuochao Zhou, Tingting Liu, Jialin Teng, Chengde Yang, Jinchao Jia, Qiongyi Hu   +23 more
wiley   +1 more source

Evaluation of bovine viral diarrhea virus (BVDV) transmission from a persistently infected goat to pregnant goats and calves

, 2014
Infections with bovine viral diarrhea virus (BVDV) occur in various artiodactyls. Persistent infections occur in non-bovine species, but rarely in goats.
Passler, T., Riddell, K. P., Edmondson, M. A., Walz, P. H., Galik, P. K., Zhang, Y.   +5 more
core   +1 more source

Traditional Uses, Phytochemistry, and Multi‐Target Pharmacological Activities of Senna alexandrina

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Senna alexandrina is a medicinally important plant with documented use across Traditional Chinese, Islamic, Ayurvedic, and Unani medicine systems. Phytochemical investigations have yielded 219 characterized compounds, predominantly anthraquinones, flavonoids, and polysaccharides, distributed across leaves, pods, and aerial parts.
Diana Afrina Rella, Khai‐Lin Hew, Yeun‐Mun Choo   +2 more
wiley   +1 more source