Okadaic Acid Is at Least as Toxic as Dinophysistoxin-1 after Repeated Administration to Mice by Gavage [PDF]
Toxins, 2023 Okadaic acid (OA) and its analogues cause diarrhetic shellfish poisoning (DSP) in humans, and risk assessments of these toxins require toxicity equivalency factors (TEFs), which represent the relative toxicities of analogues.
Se Yong Park +6 more
doaj +2 more sources
Identification of 19-epi-okadaic Acid, a New Diarrhetic Shellfish Poisoning Toxin, by Liquid Chromatography with Mass Spectrometry Detection [PDF]
Marine Drugs, 2008 Okadaic acid (1) (OA) and its congeners are mainly responsible for diarrhetic shellfish poisoning (DSP) syndrome. The presence of several OA derivatives have already been confirmed in Prorocentrum and Dinophysis spp.
José J. Fernández +5 more
doaj +2 more sources
Okadaic Acid Meet and Greet: An Insight into Detection Methods, Response Strategies and Genotoxic Effects in Marine Invertebrates [PDF]
Marine Drugs, 2013 Harmful Algal Blooms (HABs) constitute one of the most important sources of contamination in the oceans, producing high concentrations of potentially harmful biotoxins that are accumulated across the food chains.
José M. Eirín-López +3 more
doaj +6 more sources
Quantitation of diarrhetic shellfish poisoning toxins in Chilean Mussel using pyrenyldiazomethane as fluorescent labeling reagent [PDF]
Biological Research, 2003 Diarrhetic shellfish poisoning (DSP) is a gastrointestinal disease caused by lipid soluble polyether toxins produced by dinoflagellates and accumulated in shellfish.
CARLOS GARCÍA +3 more
doaj +7 more sources
Diarrhetic Shellfish Toxins and Other Lipophilic Toxins of Human Health Concern in Washington State
Marine Drugs, 2013 The illness of three people in 2011 after their ingestion of mussels collected from Sequim Bay State Park, Washington State, USA, demonstrated the need to monitor diarrhetic shellfish toxins (DSTs) in Washington State for the protection of human health ...
Bich-Thuy L. Eberhart +7 more
doaj +3 more sources
The CHROMEVALOA Database: A Resource for the Evaluation of Okadaic Acid Contamination in the Marine Environment Based on the Chromatin-Associated Transcriptome of the Mussel Mytilus galloprovincialis [PDF]
Marine Drugs, 2013 Okadaic Acid (OA) constitutes the main active principle in Diarrhetic Shellfish Poisoning (DSP) toxins produced during Harmful Algal Blooms (HABs), representing a serious threat for human consumers of edible shellfish.
José M. Eirín-López +8 more
doaj +5 more sources
Molecular Mechanisms of Algicidal Bacteria in Controlling Harmful Algal Blooms: Advances in Bacteria‐Algae Interactions [PDF]
Environ Microbiol RepThis review elucidates the molecular mechanisms of algicidal bacteria, highlighting critical behaviours like chemotaxis, quorum sensing and extracellular vesicle release. It details how these actions disrupt algal cellular integrity, photosynthesis and calcium homeostasis, providing a theoretical foundation for controlling harmful algal blooms ...
Wang J, Xu B, Huang L.
europepmc +2 more sources
Analytical Sciences, 2018 Okadaic acid (OA) and saxitoxin (STX) are typical toxins of diarrhetic shellfish poisoning (DSP) and paralytic shellfish poisoning (PSP), respectively, which are highly toxic marine toxins threatening human health and environmental safety. OA is a potent inhibitor of serine/threonine protein phosphatases that can cause cellular death, while STX is an ...
Hongbo, Li +6 more
openaire +5 more sources
Drastic hypothermia after intraperitoneal injection of okadaic acid, a diarrhetic shellfish poisoning toxin, in mice. [PDF]
Exp Anim, 2021 Suzuki H.
europepmc +2 more sources
New evidence of pectenotoxins in farmed bivalve molluscs from Sardinia (Italy)
Italian Journal of Food Safety, 2021 Several planktonic dinoflagellates can produce lipophilic phycotoxins that represent a significant threat to public health as well as to shellfish and fish farming.
Alessandro G. Mudadu +12 more
doaj +1 more source