Results 121 to 130 of about 90,051 (360)

The mediating role of the left ventricular mass index on the relationship between the fluid balance and left ventricular diastolic function in patients with chronic kidney disease [PDF]

open access: yesKidney Research and Clinical Practice
Background The pathophysiological mechanism of cardiovascular disease in patients with chronic kidney disease (CKD) is complicated. Mediation analysis is an important statistical tool for gaining insight into the complex mechanisms of exposure-outcome ...
Byoung-Geun Han   +4 more
doaj   +1 more source

Assessment Of Response To Heart Failure Therapy: Ventricular Volume Changes Versus Shape Changes [PDF]

open access: yes, 2011
The prolate ellipsoid left ventricular geometry is crucial for its unique contraction and relaxation patterns. Perturbations in optimal cardiac function preceding overt heart failure ensue when this ellipsoid shape assumes a more spherical configuration.
Srilakshmi Adhyapak, V.Rao Parachuri
core   +1 more source

Multiomics and Systematic Analyses Reveal the Roles of Hemoglobin and the HIF‐1 Pathway in Polycystic Ovary Syndrome

open access: yesAdvanced Science, EarlyView.
High‐end normal hemoglobin levels are associated with an increased odds of polycystic ovary syndrome (PCOS), potentially through a mechanism of elevating testosterone levels involving the hypoxia‐inducible factor 1 (HIF‐1) pathway. These findings provide novel insights into the pathophysiology of PCOS and highlight that hemoglobin levels may serve as a
Guiquan Wang   +13 more
wiley   +1 more source

Age‐related changes in the coronary microcirculation influencing the diagnostic performance of invasive pressure‐based indices and long‐term patient prognosis

open access: yesCatheterization and Cardiovascular Interventions, Volume 100, Issue 7, Page 1195-1205, December 1, 2022., 2022
Abstract Objectives Investigate age‐related changes in coronary microvascular function, its effect on hyperemic and non‐hyperemic indices of stenosis relevance, and its prognostic implications. Background Evidence assessing the effect of age on fractional flow reserve (FFR), resting mean distal intracoronary pressure/mean aortic pressure (Pd/Pa), and ...
Daniel Faria   +15 more
wiley   +1 more source

Changes and classification in myocardial contractile function in the left ventricle following acute myocardial infarction [PDF]

open access: yes, 2017
In this research, we hypothesized that novel biomechanical parameters are discriminative in patients following acute ST-segment elevation myocardial infarction (STEMI).
Aderhold, Andrej   +5 more
core   +1 more source

P21‐Activated Kinase 2 as a Novel Target for Ventricular Tachyarrhythmias Associated with Cardiac Adrenergic Stress and Hypertrophy

open access: yesAdvanced Science, EarlyView.
Ca2+/calmodulin‐dependent kinase II (CaMKII) activation is likely driven by oxidative stress, particularly excessive reactive oxygen species (ROS) production. This study identifies P21‐activated kinase 2 (Pak2) as a novel regulator of ROS‐induced CaMKII activation and abnormal Ca2⁺ dynamics in acute adrenergic and chronic pressure‐overload stressed ...
Tao Li   +21 more
wiley   +1 more source

Transcatheter valve repair of tricuspid regurgitation with the PASCAL system: TriCLASP study 30‐day results

open access: yesCatheterization and Cardiovascular Interventions, Volume 100, Issue 7, Page 1291-1299, December 1, 2022., 2022
Abstract Background Severe tricuspid regurgitation (TR) is independently associated with increased morbidity and mortality. Percutaneous transcatheter approaches may offer an alternative for patients not amenable to surgery. Methods TriCLASP is a prospective, single‐arm, multicenter European post‐market clinical follow‐up study (NCT04614402) to ...
Stephan Baldus   +18 more
wiley   +1 more source

The volumetric analysis of cardiac chambers and three-dimensional cardiac reconstruction during chicken embryo cardiogenesis [PDF]

open access: yesМорфологія, 2011
Aim of this study was to quantitatively examine chicken heart’s parameters at the stage HH 29 and HH 35 (Hamburger and Hamilton, 1951). It was achieved by using three-dimensional (3D) reconstruction software to align multiple histological sections of the
Goodlett T.
doaj  

VARIABILITAS TEKANAN DARAH INTRADIALISIS PASIEN PENYAKIT GINJAL KRONIS DENGAN HEMODIALISIS BERKELANJUTAN

open access: yesMajalah Biomorfologi, 2019
Background: Various of studies report there was a link between changes in blood pressure during hemodialysis and the level of patient’s morbidity and mortality.
Maulana Muhtadin Suryansyah   +2 more
doaj   +1 more source

A Novel Mathematical/Numerical Formula for Assessing Right Ventricular Torsion Using Echocardiographic Imaging [PDF]

open access: yesarXiv, 2015
Recently, the ventricular torsional parameters have received special attention because of their significant role in the ventricular systolic and diastolic function. Right ventricular (RV) rotational deformation is a sensitive index for RV performance but difficult to measure.
arxiv  

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