Results 101 to 110 of about 310,541 (335)

Prognostic impact of cardiac dysfunctions in patients with ST-segment elevation myocardial infarction

open access: yesAmerican Heart Journal Plus
Background: The incidence and impact of cardiac dysfunctions after ST-segment elevation myocardial infarction (STEMI) are not understood. We aimed to characterize the prevalence of follow-up systolic and diastolic dysfunction and their associations with ...
Yan Zhou   +12 more
doaj   +1 more source

Left Ventricular Diastolic Dysfunction in Dialysis Patients Assessed by Novel Speckle Tracking Strain Rate Analysis: Prevalence and Determinants

open access: yesInternational Journal of Nephrology, 2012
Background. Diastolic dysfunction is common among dialysis patients and is associated with increased morbidity and mortality. Novel echocardiographic speckle tracking strain analysis permits accurate assessment of left ventricular diastolic function ...
Mihály K. de Bie   +9 more
doaj   +1 more source

Structural and functional changes in the heart and clinical features of heart failure with preserved left ventricular ejection fraction in patients after myocardial infarction, comorbided with arterial hypertension

open access: yesZaporožskij Medicinskij Žurnal, 2013
Recently, much attention was paid to left ventricular diastolic dysfunction and its role in the occurrence of chronic heart failure. In patients after myocardial infarction, diastolic dysfunction often precedes systolic dysfunction and predicts prognosis.
V. D. Syvolap, Ya. V. Zemlyaniy
doaj   +1 more source

Left ventricular mass and intrarenal arterial stiffness as early diagnostic markers in cardiorenal syndrome type 5 due to systemic sclerosis [PDF]

open access: yes, 2016
Background: Cardiorenal syndrome type 5 (CRS-5) includes a group of conditions characterized by a simultaneous involvement of the heart and kidney in the course of a systemic disease.
AMOROSO, Antonio   +11 more
core   +1 more source

Development of an efficient mice model of cancer‐associated cardiac cachexia

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This work establishes a preclinical framework for targeting ubiquitin pathways to mitigate the morbidity of cancer‐related cardiopathy. Our integrated approach delineates a hierarchical progression from subcellular dysfunction to macroscopic cardiac deterioration. These findings mechanistically link tumor‐induced cachexia to cardiac dysfunction through
Shijie Xiong   +9 more
wiley   +1 more source

Soluble ST2 levels and left ventricular structure and function in patients with metabolic syndrome [PDF]

open access: yes, 2016
Background: A biomarker that is of great interest in relation to adverse cardiovascular events is soluble ST2 (sST2), a member of the interleukin family.
Beunza, Maite   +14 more
core   +1 more source

Pimobendan alleviates myocyte apoptosis and fibrosis associated with mitral regurgitation by targeting endoplasmic reticulum stress

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Mitral regurgitation (MR) causes volume overload and disrupts Ca2+ homeostasis. The volume overload leads to cardiac hypertrophy and fibrosis inferred from histopathological studies. Cardiac hypertrophy was identified by increased myocyte cross‐sectional area, left atrial‐to‐aortic root ratio, and left ventricular internal diameter at end‐diastole ...
Pakit Boonpala   +10 more
wiley   +1 more source

The use of transgenic animals for xenotransplantation: An update

open access: yesAnimal Models and Experimental Medicine, EarlyView.
One way to produce genetically modified pigs is to use somatic cell nuclear transfer (SCNT). This procedure involves removing the metaphase plate from a mature oocyte using micromanipulation and then transferring the modified nucleus from the donor somatic cell to the oocyte.
Julia Motławska   +3 more
wiley   +1 more source

Human cardiomyocyte calcium handling and transverse tubules in mid-stage of post-myocardial-infarction heart failure [PDF]

open access: yes, 2018
Aims: Cellular processes in the heart rely mainly on studies from experimental animal models or explanted hearts from patients with terminal end-stage heart failure (HF).
Condorelli, Gianluigi   +12 more
core   +2 more sources

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