Results 31 to 40 of about 316,318 (334)

Repolarization Dispersion Is Associated With Diastolic Electromechanical Discoordination in Children With Pulmonary Arterial Hypertension

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Electromechanical dyssynchrony is a well described comorbidity in pulmonary arterial hypertension (PAH). ECG‐derived measurements reflective of diastolic dysfunction and electromechanical imaging markers are yet to be investigated.
Michal Schäfer, Benjamin S. Frank, D. Dunbar Ivy, Max B. Mitchell, Kathryn K. Collins, Pei‐Ni Jone, Johannes C. von Alvensleben   +6 more
doaj   +1 more source

Decreased soluble guanylate cyclase contributes to cardiac dysfunction induced by chronic doxorubicin treatment in mice [PDF]

, 2017
Aims: The use of doxorubicin, a potent chemotherapeutic agent, is limited by cardiotoxicity. We tested the hypothesis that decreased soluble guanylate cyclase (sGC) enzyme activity contributes to the development of doxorubicin-induced cardiotoxicity ...
Allen, Kaitlin, Bartunek, Jozef, Beerens, Manu, Bloch, Donald B, Bloch, Kenneth D, Brouckaert, Peter, Buys, Emmanuel S, Caluwe, Ellen, Gillijns, Hilde, Janssens, Stefan P, Nathan, Daniel I, Scherrer-Crosbie, Marielle, Swinnen, Melissa, Tainsh, Robert E, Vandenwijngaert, Sara, Walravens, Ann-Sophie   +15 more
core   +1 more source

Increased circulating ANG II and TNF-α represents important risk factors in obese Saudi adults with hypertension irrespective of diabetic status and BMI [PDF]

, 2012
Central adiposity is a significant determinant of obesity-related hypertension risk, which may arise due to the pathogenic inflammatory nature of the abdominal fat depot.
A Berrington de Gonzalez, A Harte, A Taube, AG Bertoni, Aimin Xu, Alison L. Harte, Amany O. Mohamed, AV Chobanian, B Chamarthi, BL Goodwin, BM Celoria, BM Cheung, C Asferg, C Asferg, C Savoia, D Gurantz, D Kalra, D Ma, ES Androulakis, F Galletti, F Galletti, G Mancia, H Itani, H Zhang, Hossam M. Draz, J Feber, J Liu, JD Fowler, JE Hall, JM do Carmo, JV Patel, K Ohashi, KF Adams, Khalid M. Alkharfy, L Alhyas, LE Bautista, Lotfi S. Bindahman, M Adamczak, M Carlyle, M Hernandez-Presa, M Pruijm, M Tohidi, M Vlasova, MA Al-Homrany, Majed S. Alokail, MY Baden, N Al-Daghri, Nasser M. Al-Daghri, NM Al-Daghri, NS Kalupahana, Omar S. Al-Attas, Philip G. McTernan, R Fogari, R Summer, RT Sabo, S Sriramula, S Yasue, Sobhy Yakout, T Wago, TA Kotchen, Tahia H. Saleem, X Gao, Y Deng, Y Takeshita   +63 more
core   +15 more sources

Association of fragmented QRS complexes on ECG with left ventricular diastolic function in hypertensive patients

Türk Kardiyoloji Derneği Arşivi, 2015
Objectives: Diastolic dysfunction occurs as a result of interstitial fibrosis in hypertensive patients. Fragmented QRS (fQRS) on ECG signifies myocardial fibrosis in various clinical situations.
Hasan Kadı, Ayşe Kevser Demir, Köksal Ceyhan, İbrahim Halil Damar, Kayıhan Karaman, Çağrı Zorlu   +5 more
doaj   +1 more source

Convenient Novel Method for Diagnosing Diastolic Dysfunction: Electrocardiographic Diastolic Index

International Journal of the Cardiovascular Academy, 2023
Background and Aim:Left ventricular diastolic dysfunction (LVDD) is the primary pathophysiology in patients with preserved ejection heart failure.
Murat Oğuz Özilhan, Özge Çakmak Karaaslan, Cem Çöteli, Orhan Maden   +3 more
doaj   +1 more source

Interval training normalizes cCardiomyocyte function, diastolic Ca²⁺ control, and SR Ca²⁺ release synchronicity in a mouse model of diabetic cardiomyopathy [PDF]

, 2009
In the present study we explored the mechanisms behind excitation-contraction (EC)-coupling defects in cardiomyocytes from mice with type-2 diabetes (db/db), and determined whether 13-weeks of aerobic interval training could restore cardiomyocyte Ca2 ...
Aasum, E., Catalucci, D., Ceci, M., Condorelli, G., Høydal, M.A., Kemi, O.J., Larsen, T., Rolim, N., Smith, G.L., Stølen, T.O., Wisløff, U.   +10 more
core   +2 more sources

Changes in left atrial deformation in hypertrophic cardiomyopathy: Evaluation by vector velocity imaging. [PDF]

, 2012
OBJECTIVES: Hypertrophic cardiomyopathy (HCM) represents a generalized myopathic process affecting both ventricular and atrial myocardium. We assessed the global and regional left atrial (LA) function and its relation to left ventricular (LV) mechanics ...
Badran, HM, Faheem, N, Hassan, H, Nazmy, A, Saadan, H, Soltan, G, Yacoub, MH   +6 more
core   +2 more sources

Functional Diagnostics Methods Comparative Assessment In Determination Of Different Diastolic Dysfunction Types [PDF]

Саратовский научно-медицинский журнал, 2009
Analysis of transmitral flow criteria has been used to underestimate diastolic dysfunction degree. The study goal was to compare the evaluation of different echocardiographic methods to determine diastolic dysfunction types.
S.A. Mironov
doaj  

Detecting impaired myocardial relaxation in sepsis with a novel tissue Doppler parameter (septal e′/s′)

Critical Care, 2017
Background Left ventricular diastolic dysfunction is associated with mortality outcomes in severe sepsis and septic shock. There are ongoing issues with diagnosing diastolic dysfunction in this cohort, partly owing to the poor applicability of ...
David J. Clancy, Michel Slama, Stephen Huang, Timothy Scully, Anthony S. McLean, Sam R. Orde   +5 more
doaj   +1 more source

Practical approach to diastolic dysfunction in light of the new guidelines and clinical applications in the operating room and in the intensive care [PDF]

, 2018
There is growing evidence both in the perioperative period and in the field of intensive care (ICU) on the association between left ventricular diastolic dysfunction (LVDD) and worse outcomes in patients.
Morelli, A., Sanfilippo, F., Scolletta, S., Vieillard-Baron, A.   +3 more
core   +1 more source