Deep phenotyping of cardiac function in heart transplant patients using cardiovascular systems models [PDF]
Heart transplant patients are followed with periodic right heart catheterizations (RHCs) to identify post-transplant complications and guide treatment. Post-transplant positive outcomes are associated with a steady reduction of right ventricular and pulmonary arterial pressures, toward normal levels of right-side pressure (about 20mmHg) measured by RHC.
arxiv
Vortex formation and instability in the left ventricle [PDF]
We study the formation of the mitral vortex ring during early diastolic filling in a patient-specific left ventricle (LV) using direct numerical simulation. The geometry of the left ventricle is reconstructed from Magnetic Resonance Imaging (MRI) data of a healthy human subject.
arxiv +1 more source
Western Diet-Fed, Aortic-Banded Ossabaw Swine: A Preclinical Model of Cardio-Metabolic Heart Failure. [PDF]
The development of new treatments for heart failure lack animal models that encompass the increasingly heterogeneous disease profile of this patient population.
Alex, Linda+22 more
core
Progression of Coronary Artery Calcium and Incident Heart Failure: The Multi-Ethnic Study of Atherosclerosis. [PDF]
BackgroundAlthough the association between coronary artery calcium (CAC) and future heart failure (HF) has been shown previously, the value of CAC progression in the prediction of HF has not been investigated.
Ambale-Venkatesh, Bharath+9 more
core +2 more sources
Total plasma sulfde in mild to moderate diastolic heart dysfunction [PDF]
Background. Te early pathophysiological mechanisms of diastolic dysfunction are not understood well. Hydrogen sulfde is an important endogenous gaseous transmitter that can infuence heart remodeling.
DRAGAN KOVAČIĆ+4 more
core +2 more sources
Experimental investigation of the flow downstream of a dysfunctional bileaflet mechanical aortic valve [PDF]
Mechanical heart valve replacement is the preferred alternative in younger patients with severe symptomatic aortic valve disease. However, thrombus and pannus formations are common complications associated with bileaflet mechanical heart valves. This leads to risks of valve leaflet dysfunction, a life threatening event.
arxiv
Early diagnosis of cardiovascular diseases in workers: role of standard and advanced echocardiography [PDF]
Cardiovascular disease (CVD) still remains the main cause of morbidity and mortality and consequently early diagnosis is of paramount importance. Working conditions can be regarded as an additional risk factor for CVD. Since different aspects of the job
Capotosto, Lidia+4 more
core +3 more sources
Objective Cardiovascular disease (CVD) is a leading cause of death in individuals with systemic lupus erythematosus (SLE). We assessed atherosclerotic plaque progression and incident cardiovascular events in patients with SLE over a 10‐year follow‐up.
Nikolaos Papazoglou+2 more
wiley +1 more source
A local optimal diastolic inequality on the two-sphere [PDF]
Using a ramified cover of the two-sphere by the torus, we prove a local optimal inequality between the diastole and the area on the two-sphere near a singular metric. This singular metric, made of two equilateral triangles glued along their boundary, has been conjectured by E.
arxiv
Left ventricular diastolic function in relation to the urinary proteome: a proof-of-concept study in a general population [PDF]
Background: In previous studies, we identified two urinary proteomic classifiers, termed HF1 and HF2, which discriminated subclinical diastolic left ventricular (LV) dysfunction from normal.
Gu, Yumei+9 more
core +2 more sources