Results 71 to 80 of about 310,541 (335)

Diastolic Dysfunction in Arterial Hypertension [PDF]

The Journal of Clinical Hypertension, 2001
Left ventricular diastolic properties are important markers of pump function and are frequently abnormal when myocardial insults alter tissue structure. Alterations can be limited to the early diastolic phase (early active relaxation) or to late diastolic filling (late ventricular compliance), but more often involve regulation of both phases of ...
DE SIMONE, GIOVANNI, PALMIERI V.
openaire   +3 more sources

Multiscale Construction, Evaluation, and Application of Organoids

Advanced Science, EarlyView.
Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma, Zhenglin Dong, Zhu'anzhen Zheng, Long Bai, Xingcai Zhang, Jiacan Su   +5 more
wiley   +1 more source

Microvascular Health as a Key Determinant of Organismal Aging

Advanced Science, EarlyView.
This review spotlights the emerging field of vascular aging, providing a comprehensive and critical overview of the molecular processes and clinical manifestations of vascular dysfunction during aging. By combining basic angioscience concepts with a critical analysis of innovative pre‐clinical aging models and lifestyle interventions, it offers a ...
Mattia Cenciarini, Andrea Uccelli, Francesca Mangili, Myriam Grunewald, Simone Bersini   +4 more
wiley   +1 more source

Left ventricular diastolic function and cardiotoxic chemotherapy

The Egyptian Heart Journal
Background Left ventricular ejection fraction falls when the myocardium has already lost a significant portion of its functional capacity. There are conflicting data on whether diastolic dysfunction precedes systolic dysfunction after cardiotoxic ...
Haider Rashid, Aamir Rashid, Asif Mattoo, Faisal R. Guru, Syed Mehvish, Shahood Ajaz Kakroo, Ajaz Ahmad Lone, Khursheed Aslam, Imran Hafeez, Hilal Rather   +9 more
doaj   +1 more source

Western Diet-Fed, Aortic-Banded Ossabaw Swine: A Preclinical Model of Cardio-Metabolic Heart Failure. [PDF]

, 2019
The development of new treatments for heart failure lack animal models that encompass the increasingly heterogeneous disease profile of this patient population.
Alex, Linda, Baines, Christopher P, Domeier, Timothy L, Edwards, Jenna C, Emter, Craig A, Ferreira-Nichols, Stephanie C, Ford, David A, Gao, Chen, Ivey, Jan R, Jones, John L, Jurrissen, Thomas J, Klutho, Paula J, Krenz, Maike, McDonald, Kerry S, Olver, T Dylan, Padilla, Jaume, Rau, Christoph, Rector, R Scott, Solaro, R John, Thorne, Pamela K, Veteto, Adam B, Wang, Yibin, Warren, Chad M   +22 more
core  

Biomass Fuel Use and Cardiac Function in Nepali Women. [PDF]

, 2020
BackgroundExposure to household air pollution (HAP) from cooking with biomass fuel affects billions of people. We hypothesized that HAP from woodsmoke, compared to other household fuels, was associated with adverse cardiovascular outcomes, of which there
Alurkar, Vijay, Balmes, John R, Bates, Michael N, Benziger, Catherine, Hooper, Laura, Kafle, Ramchandra, Kaufman, Joel D, Pope, Karl, Sijali, Tula R, Tiwana, Jasleen   +9 more
core   +2 more sources

Thyroid hormone levels within reference range are associated with heart rate, cardiac structure, and function in middle-aged men and women [PDF]

, 2013
Background: Triiodothyronine (T3) has many effects on the heart, and marked changes in cardiac function and structure occur in patients with (subclinical) thyroid disease. We investigated whether between-subject variation in thyroid hormone levels within
De Buyzere, Marc, Gillebert, Thierry, Kaufman, Jean, Rietzschel, Ernst, ROEF, GREET, Taes, Youri, Van daele, Caroline   +6 more
core   +1 more source

Role of estrogen in diastolic dysfunction

American Journal of Physiology-Heart and Circulatory Physiology, 2014
The prevalence of left ventricular diastolic dysfunction (LVDD) sharply increases in women after menopause and may lead to heart failure. While evidence suggests that estrogens protect the premenopausal heart from hypertension and ventricular remodeling, the specific mechanisms involved remain elusive.
Zhuo, Zhao, Hao, Wang, Jewell A, Jessup, Sarah H, Lindsey, Mark C, Chappell, Leanne, Groban   +5 more
openaire   +3 more sources

Evolution and outcome of diastolic dysfunction [PDF]

Heart, 2008
Background: Diastolic dysfunction (DD) is highly prevalent and associated with increased morbidity and mortality, but its natural history remains poorly defined. Objective: This cohort study sought to characterise the influence of clinical features,
Achong, Naomi, Wahi, Sudhir, Marwick, Thomas H.   +2 more
openaire   +3 more sources

Development of Age‐ and Sex‐Specific Metabolomics‐Based Biological Ageing Clocks for 10‐Year Mortality Prediction

Advanced Science, EarlyView.
Metabolomics‐based ageing clocks developed using blood biomarkers from over 215 000 European adults, improved the prediction of 10‐year all‐cause mortality compared to traditional models. Biological age acceleration is associated with higher mortality risk, as each additional year of metabolic age corresponded to at least 8% increased risk. These tools
Lei Peng, Ruijie Xie, Bernd Holleczek, Hermann Brenner, Ben Schöttker   +4 more
wiley   +1 more source