Evaluation of Sedative and Hypnotic Effects and Acute Toxicity of Paeonia daurica subsp. macrophylla (Albov) D.Y.Hong Root Extracts in Mice [PDF]
Research Journal of Pharmacognosy, 2023 Background and objectives: Paeonia daurica ssp. macrophylla (PD) (Paeoniaceae) is a perennial plant, growing in Iran. In Persian medicine, another species, Paeonia officinalis “Oode-saleeb” has been used especially for treating epilepsy and brain ...
Hamid Reza Monsef-Esfahani +5 more
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Experimental versus theoretical log D7.4, pKa and plasma protein binding values for benzodiazepines appearing as new psychoactive substances [PDF]
, 2018 The misuse of benzodiazepines as new psychoactive substances is an increasing problem around the world. Basic physicochemical and pharmacokinetic data is required on these substances in order to interpret and predict their effects upon humans ...
Manchester, Kieran R. +2 more
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BMC Health Services Research, 2019 Background The use of psychotropic substances is controlled in most parts of the world due to their potential of abuse and addiction. Diazepam is one of the psychotropic substances which can be dispensed in community pharmacies in Tanzania.
Wigilya Padili Mikomangwa +6 more
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Treatments for spasticity and pain in multiple sclerosis: a systematic review [PDF]
, 2003 Objectives: To identify the drug treatments currently available for the management of spasticity and pain in multiple sclerosis (MS), and to evaluate their clinical and cost-effectiveness.
Beard, S.M., Hunn, A., Wight, J.
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Clinical considerations in transitioning patients with epilepsy from clonazepam to clobazam: a case series. [PDF]
, 2014 IntroductionIn treating refractory epilepsy, many clinicians are interested in methods used to transition patients receiving clonazepam to clobazam to maintain or increase seizure control, improve tolerability of patients' overall drug therapy regimens ...
Chung, Steve +4 more
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Oral Diazepam in Febrile Seizures Following Acellular Pertussis Vaccination
Advanced Biomedical Research, 2019 Background: Febrile seizure is the most common type of seizures among children, which is a terrible and frightening experience for parents who are concerned about its recurrence.
Mohammadreza Ghazavi +3 more
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Tetramethylenedisulfotetramine alters Ca²⁺ dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation. [PDF]
, 2012 Tetramethylenedisulfotetramine (TETS) is a potent convulsant that is considered a chemical threat agent. We characterized TETS as an activator of spontaneous Ca²⁺ oscillations and electrical burst discharges in mouse hippocampal neuronal cultures at 13 ...
Cao, Zhengyu +5 more
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Biochemical and toxicological effect of diazepam in stress-induced cardiac dysfunctions
Toxicology Reports, 2020 Diazepam is a medicine of the family benzodiazepine, used to treat various CNS disorders. To date, no study is available for biochemical analysis of diazepam in cardiac dysfunction.
Fahad A. Al-Abbasi +2 more
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Sari Pediatri, 2018 Latar belakang. Literatur terbaru menunjukkan bahwa midazolam yang diberikan secara non-intravena memungkinkan untuk pemberian yang lebih cepat, sama efektif, dan aman bila dibandingkan dengan diazepam IV dalam mengatasi kejang akut pada anak.
Achmad Rafli, Setyo Handryastuti
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Titanocene anticancer complexes and their binding mode of action to human serum albumin: a computational study [PDF]
, 2011 Due to the pivotal role played by human serum albumin (HSA) in the transport and cytotoxicity of titanocene complexes, a docking study has been performed on a selected set of titanocene complexes to aid in the current understanding of the potential mode ...
Nutt, David R. +3 more
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