Results 21 to 30 of about 83,280 (287)
Diazepam causes sedative rather than anxiolytic effects in C57BL/6J mice
Scientific Reports, 2021 Diazepam has been broadly accepted as an anxiolytic drug and is often used as a positive control in behavioral experiments with mice. However, as opposed to this general assumption, the effect of diazepam on mouse behavior can be considered rather ...
Marina Pádua-Reis +3 more
doaj +1 more source
Neuropsychopharmacology Reports, Volume 42, Issue 4, Page 421-429, December 2022., 2022 Abstract Background Depression is a common disorder that affects patients' quality of life and incurs health system costs. Due to the resistance to treat depression, better understanding of neurophysiology was considered; one of the implications is the glutamatergic system.
Ahmad Shamabadi
wiley +1 more source
Neuropsychopharmacology Reports, Volume 42, Issue 4, Page 457-467, December 2022., 2022 By using a wearable sensor we examined 3‐dimensional acceleration and heart rate variability (HRV) simultaneously in depressive episode of mood disorders. We found reduced activity and altered HRV indices in depressed patients, compared with healthy participants, particularly in males. Moreover, we found that sympathetic load during sleep significantly
Norie Koga +6 more
wiley +1 more source
Neuropsychopharmacology Reports, Volume 42, Issue 4, Page 502-509, December 2022., 2022 Abstract Aims The Guidelines for the Pharmacotherapy of Schizophrenia were established to improve the quality of medical care, and the EGUIDE project was conducted to train clinicians on guideline usage. A quality indicator (QI) was established to measure the prevalence of the guidelines, and a survey was conducted, which revealed a gap between the ...
Ken Inada +38 more
wiley +1 more source
Journal of Advanced Veterinary and Animal Research, 2014 The comparative efficacy of Diazepam, Ketamine, and Ketamine-Diazepam combination was assessed in adult chickens. The chickens (n=30) were divided into three equal groups (G-1, G-2 and G-3), and were administered with Diazepam dosed at 0.5 mg/kg body ...
Muhammad Abdullahi Mahmud +5 more
doaj +1 more source
Pharmacoepidemiology and Drug Safety, Volume 32, Issue 1, Page 60-65, January 2023., 2023 Abstract Purpose To analyse (1) how often patients insured under the statutory health insurance (SHI) scheme received repeated prescriptions for benzodiazepines or Z‐drugs as private prescriptions and (2) how often doctors switched from SHI prescriptions to private prescriptions and vice versa when issuing repeat prescriptions.
Thomas Grimmsmann, Wolfgang Himmel
wiley +1 more source
BMC Health Services Research, 2019 Background The use of psychotropic substances is controlled in most parts of the world due to their potential of abuse and addiction. Diazepam is one of the psychotropic substances which can be dispensed in community pharmacies in Tanzania.
Wigilya Padili Mikomangwa +6 more
doaj +1 more source
International Journal of Neuropsychopharmacology, 2016 Background: Loss of parvalbumin interneurons in the hippocampus is a robust finding in schizophrenia brains. Rats exposed during embryonic day 17 to methylazoxymethanol acetate exhibit characteristics consistent with an animal model of schizophrenia ...
Yijuan Du, A. Grace
semanticscholar +1 more source
Veterinary Record, Volume 191, Issue 11, 3/10 December 2022., 2022 Abstract Background Weddell seals (Leptonychotes weddellii) are a well‐studied species of phocid with an apparent sensitivity to immobilising agents. Mortality as high as 31% has been reported during field immobilisation. This study investigated the use of a benzodiazepine in combination with an opioid agonist/antagonist for sedation in Weddell seal ...
Sophie Whoriskey +6 more
wiley +1 more source
Evaluation of Sedative and Hypnotic Effects and Acute Toxicity of Paeonia daurica subsp. macrophylla (Albov) D.Y.Hong Root Extracts in Mice [PDF]
Research Journal of Pharmacognosy, 2023 Background and objectives: Paeonia daurica ssp. macrophylla (PD) (Paeoniaceae) is a perennial plant, growing in Iran. In Persian medicine, another species, Paeonia officinalis “Oode-saleeb” has been used especially for treating epilepsy and brain ...
Hamid Reza Monsef-Esfahani +5 more
doaj +1 more source