Results 81 to 90 of about 144,206 (380)

Current practices in managing acutely disturbed patients at three hospitals in Rio de Janeiro-Brazil: a prevalence study [PDF]

, 2002
The medical management of aggressive and violent behaviour is a critical situation for which there is little evidence. In order to prepare for a randomised trial, due to start in the psychiatric emergency rooms of Rio de Janeiro in 2001, a survey of ...
Adams, C.E., Carvalho, A, Coutinho, E, Fagundes, H.M., Gewandszajder, M, Huf, G, Keusen, A, Lopez, J, Oliveira, E.S.   +8 more
core  

Structural Insights into Differences in Drug-binding Selectivity between Two Forms of Human α1-Acid Glycoprotein Genetic Variants, the A and F1*S Forms [PDF]

, 2011
Human α1-acid glycoprotein (hAGP) in serum functions as a carrier of basic drugs. In most individuals, hAGP exists as a mixture of two genetic variants, the F1*S and A variants, which bind drugs with different selectivities. We prepared a mutant of the A
Curry, S, Fukunaga, N, Izumi, M, Maruyama, T, Nakamura, T, Nishi, K, Ono, T, Otagiri, M, Suenaga, A, Watanabe, H, Yamagata, Y   +10 more
core   +2 more sources

GABAA Receptor α Subunits Differentially Contribute to Diazepam Tolerance after Chronic Treatment

PLoS ONE, 2012
Background Within the GABAA-receptor field, two important questions are what molecular mechanisms underlie benzodiazepine tolerance, and whether tolerance can be ascribed to certain GABAA-receptor subtypes.
C. Vinkers, R. van Oorschot, E. Nielsen, J. Cook, H. H. Hansen, L. Groenink, B. Olivier, N. Mirza   +7 more
semanticscholar   +1 more source

Comparative Effect of African Walnut Oil and Docosahexaenoic Acid on, Cancer Antigen C15‐3, Biochemical and Histopathological Markers of Female Wistar Rats With 7,12‐Dimethylbenz[a]anthracene‐Induced Breast Cancer

Cancer Nexus, EarlyView.
ABSTRACT This work compares the effect of African walnut oil and docosahexaenoic acid (DHA) on cancer antigen C15‐3 (CA15‐3), biochemical, and histopathological markers of rats with 7,12‐dimethylbenz[a]anthracene‐induced (DMBA) breast cancer. 18 rats with tumor were randomized into three groups of six rats each: The negative control, the positive ...
Fabrice Tonfack Djikeng, Brenda Sandrine Tiadjo, Eurydice Flore Tiepma Ngongang, Hilaire Macaire Womeni   +3 more
wiley   +1 more source

Implications of Seizure-Cluster Treatment on Healthcare Utilization: Use of Approved Rescue Medications

Neuropsychiatric Disease and Treatment, 2022
Adrian L Rabinowicz,1 Edward Faught,2 David F Cook,1 Enrique Carrazana1,3 1Clinical Development & Medical Affairs, Neurelis, Inc., San Diego, CA, USA; 2Emory Epilepsy Program, Emory University School of Medicine, Atlanta, GA, USA; 3John A.
Rabinowicz AL, Faught E, Cook DF, Carrazana E   +3 more
doaj  

Structure of Heteropentameric GABAA Receptors and Receptor-Anchoring Properties of Gephyrin

Frontiers in Molecular Neuroscience, 2019
γ-Aminobutyric acid type A receptors (GABAARs) mediate the majority of fast synaptic inhibition in the central nervous system (CNS). GABAARs belong to the Cys-loop superfamily of pentameric ligand-gated ion channels (pLGIC) and are assembled from 19 ...
Vikram Babu Kasaragod, Hermann Schindelin   +1 more
doaj   +1 more source

Bacterio-plankton transformation of diazepam and 2-amino-5-chlorobenzophenone in river waters. [PDF]

, 2014
Benzodiazepines are a large class of commonly-prescribed drugs used to treat a variety of clinical disorders. They have been shown to produce ecological effects at environmental concentrations, making understanding their fate in aquatic environments very
Ainsworth, Bianchi, Boxall, Brodin, Brooks, Calisto, Calisto, Cole, Crump, Diaz-Cruz, Gardolinski, Griffiths, Guenet, Halling-Sørensen, Helbling, Holmes, Ibekwe, Kan, Kosjek, Kümmerer, Lane, Liu, Loffler, Muyzer, Muyzer, Nercessian, Onesios-Barry, Porter, Shimp, Straub, Stuer-Lauridsen, Suzuki, Tappin, Tappin, Ternes, Verlicchi, West, WHO, Yoon, Zuccato   +39 more
core   +3 more sources

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

PERBANDINGAN PERUBAHAN LAJU NADI PADA PREMEDIKASI ANTARA DIAZEPAM DAN MIDAZOLAM PADA SPINAL ANESTESI [PDF]

, 2015
Iwing Dwi Purwandi, G0099094, 2006 PERBANDINGAN PERUBAHAN LAJU NADI PADA PREMEDIKASI ANTARA DIAZEPAM DAN MIDAZOLAM PADA SPINAL ANESTESI, Fakultas Kedokteran Universitas Sebelas Maret Dalam anestesiologi, tindakan monitoring sangat vital dalam menjaga ...
PURWANDI, IWING DWI
core  

Complexation between oleanolic and maslinic acids with native and modified cyclodextrins [PDF]

, 2018
Oleanolic (OA) and maslinic (MA) acids are two natural triterpenoids with a wide range of beneficial effects for human health. However, their low solubility and permeability make their application in the food or industry difficult. The complexation of OA
López Miranda, Santiago
core   +2 more sources