Results 181 to 190 of about 41,308 (256)

Proteomic Profiling of Xenobiotic and Nutrient Transporters in Human Placenta of Different Gestational Ages

Clinical Pharmacology &Therapeutics, EarlyView.
The placenta serves a critical role in nutrient uptake and waste elimination for the developing fetus. The placenta is also responsible for the uptake and/or exchange of xenobiotics, including medications, between the maternal and fetal bloodstreams. An estimated 40–80% of women take medications or drugs during pregnancy.
Eric M. Weaver, Ariel Topletz‐Erickson, Edward J. Kelly, Joanne Wang, Nina Isoherranen, Jashvant D. Unadkat, Samuel L.M. Arnold   +6 more
wiley   +1 more source

DICER cleavage fidelity is governed by 5'-end binding pockets. [PDF]

Nature
Ngo MK, Le CT, Nguyen TA.
europepmc   +1 more source

Electron‐Rich Para‐Methylpyridine‐Functionalized TEMPO Empowers Long‐Lived Neutral Aqueous Organic Redox Flow Batteries

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Three methylpyridine‐functionalized TEMPOs were synthesized through an electron‐rich regulation strategy. The calculation of transition states supported the highest reaction efficiency of para‐MePy‐TEMPOs, which outperformed its analogues to have the best performance of AORFBs, opening a new avenue for exploring TEMPO‐based catholytes.
Shaopeng Wang, Xuri Zhang, Jianyue He, Junjie Huang, Chi Han, Zhikun Xu, Puiki Leung, Xinhui Fan, Sikun Zhang, Xu Liu, Gang He   +10 more
wiley   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

MiSiPi.Rna: an integrated tool for characterizing small regulatory RNA processing. [PDF]

RNA
Jarva T, Baugh C, Zhang J, Lai EC, Flynt A.   +4 more
europepmc   +1 more source

Automated segmentation of postsurgical resection cavities on magnetic resonance imaging in focal epilepsy: A Multicentre Epilepsy Lesion Detection study

Epilepsia, EarlyView.
Abstract Objective Quantitative assessment of extent of tissue resection following epilepsy surgery requires accurate delineation of the resection cavity on postoperative magnetic resonance imaging (MRI). Current methods for resection cavity masking are time‐consuming and labor‐intensive, and existing automated approaches exhibit variable segmentation ...
Jieun Seo, Mathilde Ripart, Helene Kaas, Cornelius Kronlage, Ben Sinclair, Lucy Vivash, Merran R. Courtney, Terence J. O'Brien, Siby Gopinath, Harilal Parasuram, Sedat Kandemirli, Natally Alarab, Lillian Lai, Marcus Likeman, Kai Zhang, Jiajie Mo, Georgian Ciobotaru, James Galea, Philip Sequeiros‐Peggs, Khalid Hamandi, Hua Xie, Venkata Sita Priyanka Illapani, William D. Gaillard, Nathan T. Cohen, Alexander G. Weil, Florence Henrichon‐Goulet, Kenza S. Lahlou, Aristides Hadjinicolaou, Agustín Ibáñez, Gonzalo M. Rojas‐Costa, Horst Urbach, Lara Bücheler, Marcel Heers, Adrián Valls Carbó, Rafael Toledano, Giulia Nobile, Costanza Parodi, Domenico Tortora, Alessandro Consales, Antonella Riva, Mariasavina Severino, Martin Tisdall, Felice D'Arco, Kshitij Mankad, Aswin Chari, Maria H. Eriksson, Rory J. Piper, J. Helen Cross, Torsten Baldeweg, Sofia González‐Ortiz, Jose Pariente, Nuria Bargalló, Yawu Liu, Reetta Kälviäinen, Carmen Barba, Matteo Lenge, Renzo Guerrini, Masaki Iwasaki, Daichi Sone, Hiroyuki Maki, Tomoki Imokawa, Noriko Sato, Julien Jung, Francisco Sepulveda, Daniel Mansilla, Andres Goycoolea, Ingeborg Lopez, Antonio Napolitano, Alessandro De Benedictis, Luca De Palma, Maria Camilla Rossi‐Espagnet, Nikolaos Kondylidis, Kostakis Gkiatis, Kyriakos Garganis, Joshua Pepper, Stefano Seri, John S. Duncan, Clarissa L. Yasuda, Lucas Scárdua‐Silva, Marina K. M. Alvim, Fernando Cendes, Antonio G. Gennari, Ruth O'Gorman Tuura, Georgia Ramantani, Mariam Josyula, Joel Stein, Nishant Sinha, Kate Davis, R. Edward Hogan, Luigi Maccotta, Sophie Adler, Konrad Wagstyl   +91 more
wiley   +1 more source

Molecular Ruler Variation in Insect Dicer-2 Suggests a Structural Basis for Species-Dependent siRNA Length and Antiviral Defense Diversity. [PDF]

Viruses
Zotti MJ, Wegner J, Farias BF, Smagghe G.   +3 more
europepmc   +1 more source

Corrigendum: Dicer-Like Genes Are Required for H2O2 and KCl Stress Responses, Pathogenicity and Small RNA Generation in Valsa mali

Frontiers in Microbiology, 2017
Hao Feng, Ming Xu, Yangyang Liu, Ruqing Dong, Xiaoning Gao, Lili Huang   +5 more
doaj   +1 more source

Non‐contrast MRI reliably captures perfusion abnormalities in status epilepticus

Epilepsia, EarlyView.
Abstract Objective To determine whether non‐contrast pseudo‐continuous arterial spin labeling (pCASL) detects status epilepticus (SE)–related perfusion abnormalities and shows quantitative correspondence with dynamic susceptibility contrast (DSC) perfusion magnetic resonance imaging (MRI), and to compare single‐slice and volumetric approaches for ...
Lukas Machegger, Pilar Bosque‐Varela, Jürgen Steinbacher, Johannes Pfaff, Eugen Trinka, Giorgi Kuchukhidze   +5 more
wiley   +1 more source

Multimodal modeling of the ictal onset zone in refractory insular epilepsy and seizure outcome of magnetic resonance‐guided laser interstitial therapy: A pediatric single‐center retrospective study

Epilepsia, EarlyView.
AbstractObjectiveThis study was undertaken to evaluate seizure outcomes after magnetic resonance‐guided laser interstitial thermal therapy (MRgLITT) in children with insular epilepsy and to assess how the extent of ablation overlaps with multimodal definitions of the ictal onset zone (IOZ).MethodsWe conducted a retrospective, single‐center study ...
Lelio Guida, Emma Losito, Sebastian Rodrigo, Catherine Chiron, Ludovic Fillon, Marie Bourgeois, Anna Kaminska, Johan Pallud, Nicole Chemaly, Volodia Dangouloff‐Ross, Stephane Aunvin, Blandine Dozieres, Rima Nabbout, Olivier David, Nathalie Boddaert, Thomas Blauwblomme   +15 more
wiley   +1 more source