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Targeting microRNA-143 in colorectal cancer: advances in molecular biosciences for biomarker-based diagnostics, therapeutic strategies, and drug resistance prediction. [PDF]
Wang X, Wang L, Ke L.
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Molecular mechanism of Tembusu virus nonstructural protein 5 antagonising RNA interference. [PDF]
Zhang M +14 more
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Infectious bronchitis-virus-like QX strain transmission, pathogenesis, replication, and host miRNA biogenesis pathway hijacking mechanism. [PDF]
Khan A +8 more
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Dicing DICER-LIKE2 roles: Identification of siRNA-independent DICER-LIKE2 functions
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DICER: structure, function, and regulation
Biophysical Reviews, 2021Regulation of gene expression by small non-coding RNAs, such as miRNAs and siRNAs, is an inherent part of complex biological processes that allow function and survival of eukaryotic cells. The type III ribonuclease DICER is widely recognized as a key step in the production of miRNAs and siRNAs, although it also has non-canonical functions such as DNA ...
Carlos A. Vergani-Junior +3 more
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Nature Plants, 2019
Global analysis revealed extensive uridylation and cytidylation at the 3’ end of plant microRNA precursors.
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Global analysis revealed extensive uridylation and cytidylation at the 3’ end of plant microRNA precursors.
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Dicer is essential for mouse development
Nature Genetics, 2003To address the biological function of RNA interference (RNAi)-related pathways in mammals, we disrupted the gene Dicer1 in mice. Loss of Dicer1 lead to lethality early in development, with Dicer1-null embryos depleted of stem cells. Coupled with our inability to generate viable Dicer1-null embryonic stem (ES) cells, this suggests a role for Dicer, and,
Emily, Bernstein +9 more
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Immunohistochemical expression of Dicer in melanoma.
Journal of Clinical Oncology, 20108591 Background: Little is known about Dicer (D) deregulation in tumour development and/or progression although several recent studies show that a decrease in D expression seems to correlate with s...
CAPALBO, CARLO +4 more
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