Results 11 to 20 of about 35,255 (199)
Antioxidants, 2022 Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) used to treat inflammatory diseases induces cellular toxicity by increasing the production of reactive oxygen species (ROS) and impairing autophagic flux.
Soohee Choi +5 more
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Therapeutic Advances in Musculoskeletal Disease, 2020 Background: Topical diclofenac, a nonsteroidal anti-inflammatory drug, has proven efficacy and safety in the management of osteoarthritis pain. We investigated penetration of topical diclofenac into knee synovial tissue and fluid (primary objective) and ...
Lothar Seefried +8 more
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Protective effects of andrographolide against diclofenac-induced gastric damage
Scientific African, 2021 The use diclofenac in pain management is limited by the development of gastric ulcers. Andrographolide is a clinically approved medicinal plant extract that has been found to possess among others, a gastro protective effect and may therefore be useful in
Augustine Tandoh +5 more
doaj +1 more source
Evaluation of Skin Penetration of Diclofenac from a Novel Topical Non Aqueous Solution: A Comparative Bioavailability Study [PDF]
Journal of Clinical and Diagnostic Research, 2015 Introduction: Different topical formulations of diclofenac have varying skin penetration profile. Recent advances in science and technology has led to the development of many new formulations of drugs for topical drug delivery. One such technological
Manish Nivsarkar +3 more
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AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Hepatotoxic Assessment of Tramadol-Diclofenac Use: A Study in a Rat Model
Biology, Medicine & Natural Product Chemistry, 2019 The concurrent use of tramadol and diclofenac may increase hepatotoxic risk due to their individual hepatotoxic effects. This study assessed the hepatotoxic effect of tramadol-diclofenac administration in albino rats.
Elias Adikwu, Ebinyo Clemente Nelson
doaj +1 more source
Molecules, 2023 Diclofenac belongs to the non-steroidal anti-inflammatory drugs with analgesic, antipyretic and anti-inflammatory effects. Diclofenac administration on the skin may be associated with the appearance of side effects. The study aimed to evaluate the impact
Wioletta Dobrzeniecka +6 more
doaj +1 more source
Enhanced Anti-Inflammatory Effects of Nanoencapsulated Diclofenac
European Journal of Inflammation, 2013 This study was conducted to compare the anti-inflammatory efficacy of nanoencapsulated and free-form diclofenac in rat. Diclofenac-loaded liposomes were prepared using the proliposome method.
J.Z. Goh +7 more
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Diclofenac topical gel in excisional wounds maintain heal quality and reduce phlogistic signals1 [PDF]
Acta Cirúrgica Brasileira, 2014 PURPOSE:To investigate diclofenac topical gel as an alternative to reduce phlogistic signals and maintain quality of wound repair.METHODS:Fifteen Wistar rats were used in this study; four excisional wounds were performed on the dorsum of each animal ...
Felipe Lobato da Silva Costa +5 more
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Inhibition of cAMP-activated intestinal chloride secretion by diclofenac: cellular mechanism and potential application in cholera. [PDF]
PLoS Neglected Tropical Diseases, 2014 Cyclic AMP-activated intestinal Cl- secretion plays an important role in pathogenesis of cholera. This study aimed to investigate the effect of diclofenac on cAMP-activated Cl- secretion, its underlying mechanisms, and possible application in the ...
Pawin Pongkorpsakol +5 more
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