Results 21 to 30 of about 35,255 (199)

The anti-inflammatory effect of allopurinol and diclofenac in chicks’ model [PDF]

Iraqi Journal of Veterinary Sciences, 2023
No studies have been conducted on the anti-inflammatory effect of allopurinol; eight-day old chicks are used. The aim of this paper was to study the anti-inflammatory action of allopurinol on a chemical pain model, both when administered alone or in ...
Maab A. Fadel, Khayrea A. Mustafa
doaj   +1 more source

Pharmacokinetic of Diclofenac in the Presence and Absence of Glibenclamide in the Rat

Journal of Pharmacy & Pharmaceutical Sciences, 2009
- PURPOSE. There is evidence that the sulfonylurea antidiabetic agent glibenclamide reduces the analgesic action of non-steroidal anti-inflammatory drugs (NSAIDs), opioids and neuromodulators in animal models. Therefore, in view of the vast clinical uses
María R. León-Reyes, Gilberto Castañeda-Hernández, Mario I Ortiz   +2 more
doaj   +1 more source

Opioid-sparing post-cesarean analgesia using intravenous diclofenac-acetaminophen combination: A prospective, randomized clinical trial

Journal of Obstetric Anaesthesia and Critical Care, 2023
Background: Current research promotes opioid-sparing analgesia as an approach to enhanced recovery after cesarean (ERAC). In developing countries, non-opioid-based analgesia is routinely practiced in obstetric settings, as opioids are not freely ...
Nidhi Bhatia, Kajal Jain, Kamlesh Kumari, Vighnesh Ashok, Ankita Dhir, Mandeep Kumar   +5 more
doaj   +1 more source

Diclofenac Synthesis

, 2021
Diclofenac is an NSAID, Non-Steroidal Anti-Inflammatory Drugs, widely used clinically in the treatement of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, and has been available in the United States since 1988 (Banks et al. 1995). Diclofenac can cause hepatotoxicity, and despite the rare nature of these events, affects a large number ...
openaire   +3 more sources

Comparison of Efficacy of Low Dose (25 mg) with High Dose Diclofenac (50 mg) in Management of Postoperative Pain after Periodontal Flap Surgery: A Randomised Clinical Trial [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: The perception of pain is highly subjective and varies substantially among individuals. Diclofenac is powerful NSAID and is associated with adverse effect, like gastric irritability.
Kshitij K Karmkar, Dilip D Khambete, Abhijit N Gurav, Rahul A Patil, Abhijeet R Shete, Sumit S Shetgar, Nibha S Kulkarni, Swapneel C Bodele   +7 more
doaj   +1 more source

Anti-inflammatory, antinociceptive and ulcerogenic activity of a zinc-diclofenac complex in rats

Brazilian Journal of Medical and Biological Research, 2004
We investigated the anti-inflammatory, antinociceptive and ulcerogenic activity of a zinc-diclofenac complex (5.5 or 11 mg/kg) in male Wistar rats (180-300 g, N = 6) and compared it to free diclofenac (5 or 10 mg/kg) and to the combination of diclofenac (
L.H. Santos, C.A.O. Feres, F.H. Melo, M.M. Coelho, M.S. Nothenberg, S. Oga, C.A. Tagliati   +6 more
doaj   +1 more source

The efficacy of pentazocine + diclofenac versus paracetamol + diclofenac for post- caesarean section analgesia

Nigerian Postgraduate Medical Journal, 2021
Background: The most common major obstetric procedure is caesarean section (CS) and one of the greatest concerns for women after CS is to have optimal pain relief. Aim: This study aims to compare the efficacy of pentazocine + diclofenac and paracetamol +
Jamila Abubakar Garba, Abubakar Abubakar Panti, Daniel C Nnadi, Ibrahim G Ango, Karima A Tunau, Saratu Bello, Saad Zubairu, Asmau'u Muhammad Nasir, Rukayya Ibrahim   +8 more
doaj   +1 more source

Antibacterial and antibiofilm activities of diclofenac against levofloxacin-resistant Stenotrophomonas maltophilia isolates; emphasizing repurposing of diclofenac

Iranian Journal of Microbiology
Background and Objectives: Stenotrophomonas maltophilia is an opportunistic pathogen causing nosocomial infections. Diclofenac is an anti-inflammatory drug that is considered a non-antibiotic drug.
Ingy El-Soudany, Ibrahim A. Abdelwahab, Marwa Atef Yakout   +2 more
doaj   +1 more source

Preparation and Characterization of Chitosan/LDH Composite Membranes for Drug Delivery Application

Membranes, 2023
In this study, composite membranes based on chitosan (CS), layered double hydroxide (LDH), and diclofenac were prepared via dispersing of LDH and diclofenac (DCF) in the chitosan matrix for gradual delivery of diclofenac sodium.
Elena-Ruxandra Radu, Andreea Madalina Pandele, Cristina Tuncel, Florin Miculescu, Stefan Ioan Voicu   +4 more
doaj   +1 more source

Photochemical characteristics of diclofenac and its photodegradation of inclusion complexes with β-cyclodextrins

Química Nova, 2012
Diclofenac is one of most frequently detected compounds in the water cycle. In this work, the effect of initial concentration, liquid inclusion complexes with β-Cyclodextrins (β-CDs) on the photodegradation of diclofenac were studied.
Minmin Qin, Haifeng Yang, Shengwen Chen, Hongyong Xie, Jie Guan   +4 more
doaj   +1 more source