Results 21 to 30 of about 56,639 (202)

Enhanced Anti-Inflammatory Effects of Nanoencapsulated Diclofenac

European Journal of Inflammation, 2013
This study was conducted to compare the anti-inflammatory efficacy of nanoencapsulated and free-form diclofenac in rat. Diclofenac-loaded liposomes were prepared using the proliposome method.
J.Z. Goh, S.N. Tang, A. Zuraini, Z.A. Zakaria, A.A. Kadir, H.S. Chiong, M.S.O. Fauzee, M.N. Hakim   +7 more
doaj   +1 more source

Diclofenac topical gel in excisional wounds maintain heal quality and reduce phlogistic signals1 [PDF]

Acta Cirúrgica Brasileira, 2014
PURPOSE:To investigate diclofenac topical gel as an alternative to reduce phlogistic signals and maintain quality of wound repair.METHODS:Fifteen Wistar rats were used in this study; four excisional wounds were performed on the dorsum of each animal ...
Felipe Lobato da Silva Costa, Laila Deprá Tiussi, Mayara Silva Nascimento, Antonio Carlos de Souza Corrêa, Edson Yuzur Yasojima, Carla Andréa Avelar Pires   +5 more
doaj   +1 more source

Diclofenac Prolongs Repolarization in Ventricular Muscle with Impaired Repolarization Reserve [PDF]

, 2012
Background: The aim of the present work was to characterize the electrophysiological effects of the non-steroidal anti- inflammatory drug diclofenac and to study the possible proarrhythmic potency of the drug in ventricular muscle.
Juhász Viktor, István Koncz, Biliczki, Péter, Kristóf Attila, Virág, László, Viktor Juhász, Papp Gyula, Papp Julius Gy, Szél Tamás, Varró András, Kristóf, Attila, Norbert Jost, András Varró, Attila Kristóf, Baczkó István, Virág László, Kohajda, Zsófia, László Virág, Husti, Zoltán, Juhász, Viktor, Zsófia Kohajda, Baczkó, István, Kohajda Zsófia, Biliczki Péter, Julius Gy Papp, Jost Norbert László, Jost, Norbert, Husti Zoltán, Varró, András, Tamás Szél, Jost Norbert, Koncz István, Péter Biliczki, Szél, Tamás, István Baczkó, Papp, Gyula, Zoltán Husti   +36 more
core   +2 more sources

Inhibition of cAMP-activated intestinal chloride secretion by diclofenac: cellular mechanism and potential application in cholera. [PDF]

PLoS Neglected Tropical Diseases, 2014
Cyclic AMP-activated intestinal Cl- secretion plays an important role in pathogenesis of cholera. This study aimed to investigate the effect of diclofenac on cAMP-activated Cl- secretion, its underlying mechanisms, and possible application in the ...
Pawin Pongkorpsakol, Nutthapoom Pathomthongtaweechai, Potjanee Srimanote, Sunhapas Soodvilai, Varanuj Chatsudthipong, Chatchai Muanprasat   +5 more
doaj   +1 more source

The anti-inflammatory effect of allopurinol and diclofenac in chicks’ model [PDF]

Iraqi Journal of Veterinary Sciences, 2023
No studies have been conducted on the anti-inflammatory effect of allopurinol; eight-day old chicks are used. The aim of this paper was to study the anti-inflammatory action of allopurinol on a chemical pain model, both when administered alone or in ...
Maab A. Fadel, Khayrea A. Mustafa
doaj   +1 more source

Anti-inflammatory, antinociceptive and ulcerogenic activity of a zinc-diclofenac complex in rats

Brazilian Journal of Medical and Biological Research, 2004
We investigated the anti-inflammatory, antinociceptive and ulcerogenic activity of a zinc-diclofenac complex (5.5 or 11 mg/kg) in male Wistar rats (180-300 g, N = 6) and compared it to free diclofenac (5 or 10 mg/kg) and to the combination of diclofenac (
L.H. Santos, C.A.O. Feres, F.H. Melo, M.M. Coelho, M.S. Nothenberg, S. Oga, C.A. Tagliati   +6 more
doaj   +1 more source

Opioid-sparing post-cesarean analgesia using intravenous diclofenac-acetaminophen combination: A prospective, randomized clinical trial

Journal of Obstetric Anaesthesia and Critical Care, 2023
Background: Current research promotes opioid-sparing analgesia as an approach to enhanced recovery after cesarean (ERAC). In developing countries, non-opioid-based analgesia is routinely practiced in obstetric settings, as opioids are not freely ...
Nidhi Bhatia, Kajal Jain, Kamlesh Kumari, Vighnesh Ashok, Ankita Dhir, Mandeep Kumar   +5 more
doaj   +1 more source

Pharmacokinetic of Diclofenac in the Presence and Absence of Glibenclamide in the Rat

Journal of Pharmacy & Pharmaceutical Sciences, 2009
- PURPOSE. There is evidence that the sulfonylurea antidiabetic agent glibenclamide reduces the analgesic action of non-steroidal anti-inflammatory drugs (NSAIDs), opioids and neuromodulators in animal models. Therefore, in view of the vast clinical uses
María R. León-Reyes, Gilberto Castañeda-Hernández, Mario I Ortiz   +2 more
doaj   +1 more source

Comparison of Efficacy of Low Dose (25 mg) with High Dose Diclofenac (50 mg) in Management of Postoperative Pain after Periodontal Flap Surgery: A Randomised Clinical Trial [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: The perception of pain is highly subjective and varies substantially among individuals. Diclofenac is powerful NSAID and is associated with adverse effect, like gastric irritability.
Kshitij K Karmkar, Dilip D Khambete, Abhijit N Gurav, Rahul A Patil, Abhijeet R Shete, Sumit S Shetgar, Nibha S Kulkarni, Swapneel C Bodele   +7 more
doaj   +1 more source

The efficacy of pentazocine + diclofenac versus paracetamol + diclofenac for post- caesarean section analgesia

Nigerian Postgraduate Medical Journal, 2021
Background: The most common major obstetric procedure is caesarean section (CS) and one of the greatest concerns for women after CS is to have optimal pain relief. Aim: This study aims to compare the efficacy of pentazocine + diclofenac and paracetamol +
Jamila Abubakar Garba, Abubakar Abubakar Panti, Daniel C Nnadi, Ibrahim G Ango, Karima A Tunau, Saratu Bello, Saad Zubairu, Asmau'u Muhammad Nasir, Rukayya Ibrahim   +8 more
doaj   +1 more source