Results 41 to 50 of about 34,990 (204)

Photochemical characteristics of diclofenac and its photodegradation of inclusion complexes with β-cyclodextrins

open access: yesQuímica Nova, 2012
Diclofenac is one of most frequently detected compounds in the water cycle. In this work, the effect of initial concentration, liquid inclusion complexes with β-Cyclodextrins (β-CDs) on the photodegradation of diclofenac were studied.
Minmin Qin   +4 more
doaj   +1 more source

Diclofenac inhibits tumor growth in a murine model of pancreatic cancer by modulation of VEGF levels and arginase activity. [PDF]

open access: yesPLoS ONE, 2010
BACKGROUND: Diclofenac is one of the oldest anti-inflammatory drugs in use. In addition to its inhibition of cyclooxygenases (COX), diclofenac potently inhibits phospholipase A(2) (PLA(2)), thus yielding a broad anti-inflammatory effect.
Nina Mayorek   +2 more
doaj   +1 more source

Shaping Carbon Nitrides for Advanced Macrostructures

open access: yesAdvanced Materials Technologies, EarlyView.
This review examines how carbon nitride can be shaped through a range of printing and interfacial assembly methods. By bringing together additive manufacturing and liquid–liquid structuring concepts, carbon nitride is moving beyond its traditional powder‐based photocatalyst form toward digitally designed robust macroscale architectures with high design
Simona Baluchová, Baris Kumru
wiley   +1 more source

Spatially Separated Redox Centers in One‐Dimensional Sp2‐Carbon Covalent Organic Frameworks Enable Synergistic Photocatalytic Palladium Recovery and Bisphenol A Mineralization

open access: yesAdvanced Science, EarlyView.
A one‐dimensional sp2‐carbon covalent organic framework with spatially segregated redox centers integrates a dual photosensitizing system and a cationic interface for synergistic photocatalysis. The material achieves exceptional palladium recovery (1749 mg g−1) and bisphenol A mineralization (0.1710 min−1) without sacrificial agents, demonstrating ...
Yi‐Ru Chen   +9 more
wiley   +1 more source

Nephroprotective activity of virgin coconut oil on diclofenac-induced oxidative nephrotoxicity is associated with antioxidant and anti-inflammatory effects in rats [PDF]

open access: yesAvicenna Journal of Phytomedicine, 2020
Objective: Diclofenac is a non-steroidal anti-inflammatory drug linked with considerable organ toxicity caused via increased generation of reactive oxygen species.
Ademola Famurewa   +5 more
doaj   +1 more source

Animal models in molecular biology research: Challenges, ethical imperatives, and the path to human‐relevant translation

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The graphical abstract shows how molecular biology research has shifted from using traditional animal models toward using methods that are more relevant to humans. It points out the main problems, differences between species, difficulty in reproducing results, moral issues, and lack of infrastructure that make translational accuracy harder to achieve ...
Md. Shajid Hossain Rafi   +6 more
wiley   +1 more source

Inhibition of COX-2 expression by topical diclofenac enhanced radiation sensitivity via enhancement of TRAIL in human prostate adenocarcinoma xenograft model

open access: yesBMC Urology, 2013
Background COX-2 inhibitors have an antitumor potential and have been verified by many researchers. Treatment of cancer cells with external stressors such as irradiation can stimulate the over-expression of COX-2 and possibly confer radiation resistance.
Inoue Takeshi   +7 more
doaj   +1 more source

New aspects of an old drug--diclofenac targets MYC and glucose metabolism in tumor cells. [PDF]

open access: yesPLoS ONE, 2013
Non-steroidal anti-inflammatory drugs such as diclofenac exhibit potent anticancer effects. Up to now these effects were mainly attributed to its classical role as COX-inhibitor. Here we show novel COX-independent effects of diclofenac.
Eva Gottfried   +16 more
doaj   +1 more source

Asymmetric Fe–Te Pairs Enhance Peroxymonosulfate Activation via Surface‐Bound Hydroxyl Radicals Pathways

open access: yesAngewandte Chemie International Edition, EarlyView.
An asymmetric Fe–Te dual‐atom pair directs peroxymonosulfate activation toward long‐lived surface‐bound hydroxyl radicals through strong p–d hybridization. The resulting electronic asymmetry enables efficient pharmaceutical degradation and reveals a metal–metalloid pairing strategy for steering reactive oxygen species pathways in advanced oxidation ...
Xuheng Li   +6 more
wiley   +1 more source

The effect of diclofenac on proliferation and production of growth factors by endothelial cells (HMEC-1) under hypoxia and inflammatory conditions

open access: yesActa Pharmaceutica, 2014
Diclofenac belongs to non-steroidal anti-inflammatory drugs (NSAIDs) and non-selective COX inhibitors. The aim of this study was to examine the effect of diclofenac on endothelial cell proliferation under the influence of hypoxia or inflammatory ...
Wiktorowska-Owczarek Anna
doaj   +1 more source

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