Results 41 to 50 of about 56,639 (202)
From Prediction to Decision Making: PBPK and QSP as Regulatory‐Grade NAMs
Clinical Pharmacology &Therapeutics, EarlyView.New approach methodologies (NAMs) encompass a diverse and rapidly evolving set of experimental and computational tools designed to generate human‐relevant mechanistic data for use in drug development and regulatory decision making. Experimental NAMs provide insights into drug disposition, pharmacological activity, and disease biology that are difficult
Karen Rowland Yeo, Piet H. van der Graaf
wiley +1 more source
The effects of indomethacin, diclofenac, and acetaminophen suppository on pain and opioids consumption after cesarean section [PDF]
Background: Cesarean section is one of the common surgeries of women. Acute post-operative pain is one of the recognized post-operative complications.
Masood Entezariasl +7 more
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EcoEnergy, EarlyView.This review deals with the recent advancements in design and engineering of BiOCl‐based Z‐scheme photocatalysts with emphasis on tailoring of structural, optoelectronic properties and heterojunction assembly for environmental applications including photodegradation of industrial organic waste, pharmaceuticals, pesticides, herbicides, toxic heavy metals,
Sakshi Sharma +7 more
wiley +1 more source
Acta Pharmaceutica, 2014 Diclofenac belongs to non-steroidal anti-inflammatory drugs (NSAIDs) and non-selective COX inhibitors. The aim of this study was to examine the effect of diclofenac on endothelial cell proliferation under the influence of hypoxia or inflammatory ...
Wiktorowska-Owczarek Anna
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New aspects of an old drug--diclofenac targets MYC and glucose metabolism in tumor cells. [PDF]
PLoS ONE, 2013 Non-steroidal anti-inflammatory drugs such as diclofenac exhibit potent anticancer effects. Up to now these effects were mainly attributed to its classical role as COX-inhibitor. Here we show novel COX-independent effects of diclofenac.
Eva Gottfried +16 more
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Научно-практическая ревматология, 2009 Objective. To assess efficacy and safety of two-month therapy with Potentilla tincturecombined with diclofenac in pts with osteoarthritis (OA) in comparison with diclofenac monotherapy (control group). Material and methods.
L N Denisov +4 more
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Advanced Science, 2021 Implant infections caused by methicillin‐resistant Staphylococcus aureus (MRSA) can cause major complications during the perioperative period. Diclofenac, one of the most widely used nonsteroidal anti‐inflammatory drugs, is often used to relieve pain and
Shutao Zhang +6 more
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Ibrain, Volume 11, Issue 1, Page 106-111, Spring 2025.A middle‐aged man presented with a right indirect inguinal hernia in November 2020 and underwent laparoscopic high ligation of the right hernial sac. Intermittent acupuncture‐like pain in the skin of the right scrotum and medial thigh occurred 1 month after surgery and lasted for 6 months. Under ultrasound guidance, ilioinguinal nerve and genitofemoral
Yong Wang +4 more
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Diclofenac sodium UV degradation [PDF]
, 2015 Diclofenac sodium (2- [2 - [(2,6-dicloro-fenil) amino] phenyl] sodium acetate) is an nonsteroidal antiinflammatory drug widely used today as an analgesic, anti-arthritic and anti-rheumatic. It is susceptible to stress caused by UV radiation. In this work
Sarno, María del Carmen Teresa +4 more
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Journal of Chemical Technology &Biotechnology, EarlyView.Abstract BACKGROUND The new European Union Wastewater Directive 2024/3019 requires upgrading sewage treatment plants to achieve 80% removal of micropollutants. This study aimed to compare different Powdered Activated Carbon dosing strategies within a hybrid Moving Bed‐Membrane Bioreactor (PAC‐MB‐MBR) system, to evaluate its performance and to study the
Athanasia Iliopoulou +8 more
wiley +1 more source