Results 31 to 40 of about 35,255 (199)

Photobiomodulation Enhances Tendon Regeneration: A Systematic Review and Meta‐analysis of Preclinical Studies

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To evaluate the preclinical evidence supporting the efficacy of photobiomodulation therapies in tendon regeneration. Methods A comprehensive literature search was conducted in MEDLINE, ScienceDirect, and Google Scholar to identify in vivo animal studies evaluating photobiomodulation therapies for tendon healing.
Yose Waluyo, Diah Nurul Islami Muchsin, Muthiah Nur Afifah, Yaldi Rosadi, M. Salas Al Aldi   +4 more
wiley   +1 more source

The impact of medication shortages on paediatric care: A retrospective impact analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Medication shortages are a growing global concern, with potentially greater consequences in paediatric patients because of the limited availability of safe, evidence‐based and appropriately formulated medication. This study aimed to evaluate the impact of medication shortages on paediatric patients by assessing the suitability and safety of ...
Maaike Johanna Rutten ‐ van Kranenburg, Laurens Christiaan van Rijn, Elisabeth Johanna Ruijgrok, Sinno Henricus Paulus Simons, Brigitta Carolina Maria Witjes, Jan‐Dietert Christoffer Brugma, Robert Bernard Flint   +6 more
wiley   +1 more source

Z‐Scheme BiOCl‐Based Photocatalysts: Recent Advances in Designing, Structural Engineering, Formation Mechanisms, and High Performance Photocatalytic Environmental Remediation

EcoEnergy, EarlyView.
This review deals with the recent advancements in design and engineering of BiOCl‐based Z‐scheme photocatalysts with emphasis on tailoring of structural, optoelectronic properties and heterojunction assembly for environmental applications including photodegradation of industrial organic waste, pharmaceuticals, pesticides, herbicides, toxic heavy metals,
Sakshi Sharma, Neha Kaushal, Victor Ezebuiro, Monika Sindhu, Lovepreet Singh, Yugesh Singh Thakur, Hendrik C. Swart, Jai Prakash   +7 more
wiley   +1 more source

Inhibition of COX-2 expression by topical diclofenac enhanced radiation sensitivity via enhancement of TRAIL in human prostate adenocarcinoma xenograft model

BMC Urology, 2013
Background COX-2 inhibitors have an antitumor potential and have been verified by many researchers. Treatment of cancer cells with external stressors such as irradiation can stimulate the over-expression of COX-2 and possibly confer radiation resistance.
Inoue Takeshi, Anai Satoshi, Onishi Sayuri, Miyake Makito, Tanaka Nobumichi, Hirayama Akihide, Fujimoto Kiyohide, Hirao Yoshihiko   +7 more
doaj   +1 more source

Nephroprotective activity of virgin coconut oil on diclofenac-induced oxidative nephrotoxicity is associated with antioxidant and anti-inflammatory effects in rats [PDF]

Avicenna Journal of Phytomedicine, 2020
Objective: Diclofenac is a non-steroidal anti-inflammatory drug linked with considerable organ toxicity caused via increased generation of reactive oxygen species.
Ademola Famurewa, Gabriel Akunna, Joseph Nwafor, Onyebuchi Chukwu, Chima Ekeleme-Egedigwe, Janet Oluniran   +5 more
doaj   +1 more source

Phytochemical profiling and bioactivity evaluation of Anthocephalus cadamba flower extracts through in vitro, and in silico studies

Food Biomacromolecules, EarlyView.
Abstract Anthocephalus cadamba (Kadamba) is a medicinally important tropical plant with well‐documented antioxidant, anti‐inflammatory, and antimicrobial properties. However, comparative evaluation of solvent extraction efficiency combined with computational validation of bioactive compounds remains limited.
Manisha Panchal, Diksha Sharma, Sunita Khatak, Raushan Kumar Jha, Surbhi Panwar, Ashwani Kumar   +5 more
wiley   +1 more source

Diclofenac inhibits tumor growth in a murine model of pancreatic cancer by modulation of VEGF levels and arginase activity. [PDF]

PLoS ONE, 2010
BACKGROUND: Diclofenac is one of the oldest anti-inflammatory drugs in use. In addition to its inhibition of cyclooxygenases (COX), diclofenac potently inhibits phospholipase A(2) (PLA(2)), thus yielding a broad anti-inflammatory effect.
Nina Mayorek, Nili Naftali-Shani, Myriam Grunewald   +2 more
doaj   +1 more source

The effect of diclofenac on proliferation and production of growth factors by endothelial cells (HMEC-1) under hypoxia and inflammatory conditions

Acta Pharmaceutica, 2014
Diclofenac belongs to non-steroidal anti-inflammatory drugs (NSAIDs) and non-selective COX inhibitors. The aim of this study was to examine the effect of diclofenac on endothelial cell proliferation under the influence of hypoxia or inflammatory ...
Wiktorowska-Owczarek Anna
doaj   +1 more source

New aspects of an old drug--diclofenac targets MYC and glucose metabolism in tumor cells. [PDF]

PLoS ONE, 2013
Non-steroidal anti-inflammatory drugs such as diclofenac exhibit potent anticancer effects. Up to now these effects were mainly attributed to its classical role as COX-inhibitor. Here we show novel COX-independent effects of diclofenac.
Eva Gottfried, Sven A Lang, Kathrin Renner, Anja Bosserhoff, Wolfram Gronwald, Michael Rehli, Sabine Einhell, Isabel Gedig, Katrin Singer, Anton Seilbeck, Andreas Mackensen, Oliver Grauer, Peter Hau, Katja Dettmer, Reinhard Andreesen, Peter J Oefner, Marina Kreutz   +16 more
doaj   +1 more source

A rare case of perineal neuralgia treated with ultrasound‐guided nerve block combined with water separation

Ibrain, Volume 11, Issue 1, Page 106-111, Spring 2025.
A middle‐aged man presented with a right indirect inguinal hernia in November 2020 and underwent laparoscopic high ligation of the right hernial sac. Intermittent acupuncture‐like pain in the skin of the right scrotum and medial thigh occurred 1 month after surgery and lasted for 6 months. Under ultrasound guidance, ilioinguinal nerve and genitofemoral
Yong Wang, Min Wang, Rui Jiang, Zhao‐Qiong Zhu, Guang‐Cai Li   +4 more
wiley   +1 more source