Results 51 to 60 of about 35,255 (199)

Cocrystal construction between the ethyl ester with parent drug of diclofenac: structural, stability, and anti-inflammatory study

open access: yesHeliyon, 2019
This study aimed to collect the crystallographic data of ethyl diclofenac and discover a cocrystal from this ester with its parent, diclofenac acid, and to investigate their physicochemical properties and anti-inflammation activity.
Ilma Nugrahani   +5 more
doaj   +1 more source

A Prediction Model for the Differential Diagnosis of Bowen's Disease and Bowenoid Actinic Keratosis

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Bowen's disease and bowenoid actinic keratosis share overlapping clinical and histopathological features, and there is no clear consensus regarding their differential diagnosis. This study aimed to identify clinicopathological differences between the two diseases and to develop a diagnostic prediction model in a Korean population.
Byeonghyun Joo   +6 more
wiley   +1 more source

Effects of diclofenac on the pharmacokinetics of celastrol in rats and its transport

open access: yesPharmaceutical Biology, 2018
Context: Diclofenac and celastrol are always used together for the treatment of rheumatoid arthritis; the herb–drug interaction potential between diclofenac and celastrol is still unknown.
Zengfu Wang, Dali Chen, Zhongwei Wang
doaj   +1 more source

Shoulder‐Tip Pain After Laparoscopic Surgery: A Narrative Review of Intraperitoneal Anaesthesia

open access: yesANZ Journal of Surgery, EarlyView.
ABSTRACT Background and Aims Shoulder‐tip pain is a common and distressing side effect following laparoscopic surgery. Standard systemic analgesic regimens are used to manage postoperative pain but are often associated with side effects such as nausea and vomiting.
Jason Arsanious   +2 more
wiley   +1 more source

Patient‐reported outcomes and visual function after four refractive strategies in cataract surgery: A randomized controlled trial

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To evaluate patient‐reported outcome measures (PROMs) and visual function across four groups of public cataract patients: emmetropia, mini‐monovision, monovision with partial‐range of field (RoF) narrow intraocular lenses (IOLs) and patients implanted with partial‐RoF extended IOLs.
Anne Guldhammer Skov   +4 more
wiley   +1 more source

Importance of the formulation in the skin delivery of topical diclofenac: not all topical diclofenac formulations are the same

open access: yesJournal of Pain Research, 2019
Julie Pradal, Coralie M Vallet, Guillaume Frappin, Frédérique Bariguian, Maria Stella LombardiDepartment of New Product Development, R&D, GSK Consumer Healthcare S.A, Nyon 1, 1260, SwitzerlandPurpose: The current study aimed to compare ...
Pradal J   +4 more
doaj  

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Salt Cocrystal of Diclofenac Sodium-L-Proline: Structural, Pseudopolymorphism, and Pharmaceutics Performance Study

open access: yesPharmaceutics, 2020
Previously, we have reported on a zwitterionic cocrystal of diclofenac acid and L-proline. However, the solubility of this multicomponent crystal was still lower than that of diclofenac sodium salt.
Ilma Nugrahani   +4 more
doaj   +1 more source

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

Effects of topical Persian medicine Amygdalus communis L. var. Amara kernel oil on the symptoms of knee osteoarthritis: a randomized, triple-blind, active, and placebo-controlled clinical trial [PDF]

open access: yesJournal of Medicinal Plants, 2023
Background: The Amygdalus communis L. var. Amara (bitter almond) kernel oil (ACKO) is used topically for palliation of musculoskeletal and joint pains in the Traditional Persian Medicine.
Saeed Kianbakht   +2 more
doaj  

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