Results 51 to 60 of about 56,639 (202)

Rational therapy of osteoarthritis

Научно-практическая ревматология, 2005
Brief information about modem osteoarthritis treatment with simple analgesics, NSAIDs and chondroprotective drugs is presented. Results of a clinical study of ARTRA in combination with diclofenac (31 pts) comparing with diclofenac only (31 pts) for the ...
E G Zotkin
doaj   +1 more source

Effect of Amoxicillin And Cefalexin on The Pharmacokinetics of Diclofenac Sodium in Healthy Volunteers [PDF]

The Medical Journal of Basrah University, 2015
Background: Studies investigating the effect of antibiotics on the pharmacokinetics of non-steroidal anti-inflammatory drugs are few. Such interaction could be clinically significant in conditions like diabetic nephropathy.
Shaima M. Ali, Nazar Haddad, Abdullah M. Jawad   +2 more
doaj   +1 more source

Gymnema sylvestre: Bioactive constituents, health benefits, and emerging applications in nutraceuticals and functional foods

JSFA reports, EarlyView.
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed, Muhammad Tauseef Sultan, Hassan Raza, Ahmad Mujtaba Noman, Nimra Haroon, Entessar Mohammad Al Jbawi   +5 more
wiley   +1 more source

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat, Yasin Turanlı, Nihat Kurt, Sefa Gözcü, Emre Tunçel, Hilal Bacanak, Eren Aytekin, Sedat Ünal   +7 more
wiley   +1 more source

Effect of iguratimod on diclofenac metabolism by CYP2C9 in rats and human recombinant CYP2C9 yeast cells

Brazilian Journal of Pharmaceutical Sciences
Iguratimod (IGU, also known as T-614), a novel disease modifying antirheumatic drug intended to cure patients with rheumatoid arthritis (RA). The purpose of this study is to evaluate the effect of IGU on the pharmacokinetics of CYP2C9 probe drug ...
Muhammad Usman, Zhu Zhen-Han, Chang Ze-Na, Han Jun-Ping, Qian Wen, Yang Chang-Qing, Nishikawa Miyu, Sakaki Toshiyuki   +7 more
doaj   +1 more source

Pre‐Extubation Low‐Dose Propofol in Pediatric Ear, Nose, and Throat Procedures: A Meta‐Analysis With Trial Sequential Analysis

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Post‐extubation emergence agitation (EA) is common in pediatric ear, nose, and throat (ENT) procedures and may lead to serious complications. Aims To assess the efficacy of low‐dose propofol administered before extubation, compared with placebo, for preventing EA, using meta‐analysis with trial sequential analysis (TSA).
Rafaela Silva, Raphaela Mendes, João Mario Borges, Henrique Pivetta, Rafael Miranda, Isabela Alles, Vinicius Oliveira, Steven Staffa, Walid Alrayashi   +8 more
wiley   +1 more source

Importance of the formulation in the skin delivery of topical diclofenac: not all topical diclofenac formulations are the same

Journal of Pain Research, 2019
Julie Pradal, Coralie M Vallet, Guillaume Frappin, Frédérique Bariguian, Maria Stella LombardiDepartment of New Product Development, R&D, GSK Consumer Healthcare S.A, Nyon 1, 1260, SwitzerlandPurpose: The current study aimed to compare ...
Pradal J, Vallet CM, Frappin G, Bariguian F, Lombardi MS   +4 more
doaj  

Effects of diclofenac on the pharmacokinetics of celastrol in rats and its transport

Pharmaceutical Biology, 2018
Context: Diclofenac and celastrol are always used together for the treatment of rheumatoid arthritis; the herb–drug interaction potential between diclofenac and celastrol is still unknown.
Zengfu Wang, Dali Chen, Zhongwei Wang
doaj   +1 more source

Electrospun PVA Scaffolds Containing MCM‐41/CNC Nanocomposites for Controlled Drug Release in Wound Dressings

Polymer Engineering &Science, EarlyView.
Cellulose nanocrystals extracted from Mauritia flexuosa petiole were combined with MCM‐41 mesoporous silica to create a diclofenac‐loaded hybrid nanocomposite. Incorporation into electrospun PVA scaffolds enabled controlled diclofenac release and high cell viability, highlighting their potential for localized drug delivery.
Karoliny V. Barbosa, Marcos G. M. Brandão, Alex Rojas, Lucas Dall Agnol, Ana Luisa C. Carvalho, Leonardo T. B. Mendonça, Ana C. S. Alcântara, Rebecca J. P. Araujo, Severino Alves Jr., Dayane K. D. N. Santos, Walter M. de Azevedo, Gricirene S. Correia   +11 more
wiley   +1 more source

Diclofenac Synthesis

, 2021
Diclofenac is an NSAID, Non-Steroidal Anti-Inflammatory Drugs, widely used clinically in the treatement of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, and has been available in the United States since 1988 (Banks et al.
Aymen Labidi
core   +2 more sources