Results 61 to 70 of about 56,639 (202)
Heliyon, 2019 This study aimed to collect the crystallographic data of ethyl diclofenac and discover a cocrystal from this ester with its parent, diclofenac acid, and to investigate their physicochemical properties and anti-inflammation activity.
Ilma Nugrahani +5 more
doaj +1 more source
Phytotherapy Research, EarlyView.ABSTRACT Asthma affects 260–300 million people worldwide. About 20%–35% of patients use medicinal plants with their asthma medication, often without telling their clinicians. Disclosure rates are low; up to 42% of asthma outpatients use herbal products, with no records in their charts.
Emine Kocyigit +5 more
wiley +1 more source
Phytotherapy Research, EarlyView.Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li +14 more
wiley +1 more source
Mass Spectrometry Imaging of Diclofenac and Its Metabolites in Tissues Using Nanospray Desorption Electrospray Ionization. [PDF]
, 2020 Glucuronidation is a common phase II metabolic process for drugs and xenobiotics which increases their solubility for excretion. Acyl glucuronides (glucuronides of carboxylic acids) present concerns of toxicity as they have been implicated in ...
Fangbiao, Li +10 more
core +2 more sources
Effects of topical Persian medicine Amygdalus communis L. var. Amara kernel oil on the symptoms of knee osteoarthritis: a randomized, triple-blind, active, and placebo-controlled clinical trial [PDF]
Journal of Medicinal Plants, 2023 Background: The Amygdalus communis L. var. Amara (bitter almond) kernel oil (ACKO) is used topically for palliation of musculoskeletal and joint pains in the Traditional Persian Medicine.
Saeed Kianbakht +2 more
doaj
Advances in Unconventional and Sustainable Synthetic Approaches to Benzopyran Scaffolds
The Chemical Record, EarlyView.This review provides a comprehensive and critical analysis of low‐impact synthetic methodologies reported in the last 8 years (2018–2026) for the construction of benzopyran‐derived scaffolds, such as coumarins, flavones, chromones, chromenes, and chromanes. The benzopyran scaffold is a versatile family of heterocycles found in a wide range of bioactive
Nathalia B. Sá +4 more
wiley +1 more source
Diclofenac topical solution compared with oral diclofenac: a pooled safety analysis
, 2011 Sanford H Roth1, Philip Fuller21Arizona Research and Education, Arthritis Laboratory, Arizona State University, Phoenix, AZ, USA; 2Medical Affairs, Covidien, Hazelwood, MO, USABackground: Topical nonsteroidal anti-inflammatory drug (NSAID) formulations ...
Philip Fuller +3 more
core +1 more source
Pharmaceutics, 2020 Previously, we have reported on a zwitterionic cocrystal of diclofenac acid and L-proline. However, the solubility of this multicomponent crystal was still lower than that of diclofenac sodium salt.
Ilma Nugrahani +4 more
doaj +1 more source
Veterinary Record, EarlyView.Abstract Background Oral non‐steroidal anti‐inflammatory drugs (NSAIDs) are commonly used for analgesia in dogs with spontaneous chronic corneal epithelial defects (SCCEDs). Topical NSAIDs can delay epithelialisation and promote stromal melting, but the safety of systemic NSAIDs in SCCEDs is unknown.
Kaitlyn Scheunemann +2 more
wiley +1 more source
Topical Diclofenac-Induced Hepatotoxicity
, 2023 The hepatotoxic potential of diclofenac, a commonly used non-steroidal antiinflammatory agent, is well established in literature. However, cases of diclofenacinduced liver disease have occurred almost exclusively with the oral formulation of this ...
Christopher J Haas +7 more
core +1 more source