Results 21 to 30 of about 30,606 (133)

Ocrelizumab‐induced colitis: VigiBase disproportionality analysis, case reports and literature review

British Journal of Clinical Pharmacology, EarlyView.
Aims Ocrelizumab is a humanized anti‐CD20 monoclonal antibody used in multiple sclerosis. Since its commercialization, several cases of ocrelizumab‐induced colitis have been reported in the scientific literature. Methods To explore the potential association of ocrelizumab with colitis as an adverse drug reaction (ADR), we conducted a descriptive and ...
Audrey Fresse, Christophe Hommel, Nadine Petitpain, Philippe Kerschen   +3 more
wiley   +1 more source

Layered double hydroxides‐based nanozymes for effective biomedical applications: A review and future perspectives

BMEMat, EarlyView.
In this review, we introduced the preparation methods of LDHzymes and discussed their catalytic activity and mechanisms. Subsequently, the applications of LDHzymes in biomedical were discussed. Finally, potential future work on LDHzymes was proposed to better design these new types of nanozymes.
Jiawei Cui, Lu Zhang, Junyi Li, Yue Chen, Sheng Dai, Manfred F. Maitz, Ansha Zhao, Ping Yang   +7 more
wiley   +1 more source

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

Clinical Pharmacology &Therapeutics, EarlyView.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi, Jessica L. Wallace, Dhakrit Rungkitwattanakul, Britney A. Stottlemyer, Tiffany L. Tran, Melanie Manis Reida, Sandra L. Kane‐Gill   +6 more
wiley   +1 more source

Fe‐Free Photocatalysis‐Self‐Fenton System for Ultraefficient Water Purification Enabled by Carbon Nitride With Strong Built‐in Electric Field

EcoEnergy, EarlyView.
This study reports a photocatalytic H₂O₂ production rate of 14.9 mmol g⁻¹ h⁻¹, representing a 22.2‐fold enhancement. Additionally, the Fe‐free PSFs achieved complete degradation of 100 mg·L⁻¹ tetracycline within 10 min across a wide pH range. ABSTRACT Photocatalytic‐self‐Fenton system (PSFs) hold great promise for water purification through in situ ...
Yuhan Yan, Hongguang Yang, Tianyu Zhou, Wei Jiang, Chunbo Liu, Guangbo Che, Bo Hu   +6 more
wiley   +1 more source

Carbon Dots: An Emerging Frontier for Green and Sustainable Civil Engineering Materials

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Traditional civil engineering materials (CE materials) are usually involved with high‐energy consumption during manufacturing, significant maintenance costs, and substantial environmental impacts throughout their life cycles. The progress of nanotechnology is catalyzing a green and sustainable transformation within the field.
Weiwen Hao, Xiaolong Wang, Xiao Chen, Dong Liu, Zhenhui Kang, Cheng Zhu   +5 more
wiley   +1 more source

Hydrophobic eutectic solvent‐engineered membranes for highly permeable, selective, and antifouling pharmaceutical removal from municipal wastewater

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Single‐step incorporation of a hydrophobic deep eutectic solvent (HDES) into polyethersulfone ultrafiltration membranes via non‐solvent induced phase separation creates selective, antifouling membranes for pharmaceutical removal. The HDES nanodomains enhance permeability, electrostatic interactions, and adsorption affinity, enabling efficient and ...
Anjali Goyal, Tarek Lemaoui, Mahendra Kumar, Ahmad S. Darwish, Ali Zerriouh, Fawzi Banat, Hassan A. Arafat, Shadi W. Hasan, Inas M. AlNashef   +8 more
wiley   +1 more source

The In Vitro Transgenic Rodent Assay in Primary MutaMouse Hepatocytes Compared to the Mammalian Cell Gene Mutation Assay Using the HPRT Gene

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT Gene mutations can be detected in mammalian cells in vitro using indicator genes such as the hypoxanthine‐guanine‐phosphoribosyltransferase (HPRT) gene. These assays have been adopted as OECD test guidelines (TG, e.g., OECD TG no. 476) and are used for regulatory purposes.
Alina Göpfert, Kylee Kendra Marie Ronnenberg, Claudia Ruelker, Silke Spang, Naveed Honarvar, Robert Landsiedel   +5 more
wiley   +1 more source

Microengineering the Liver: Strategies for Constructing Functional Liver‐on‐a‐Chip Devices

Exploration, EarlyView.
This review summarizes recent advances in liver‐on‐a‐chip (LOC) technologies, including fabrication strategies and functional integration approaches, and discusses their promising applications in drug screening and related biomedical fields. ABSTRACT Reliable in vitro liver models are indispensable for researching liver diseases and developing ...
Jie Wang, Ziwei Liang, Jiapu Wang, Zongyi Li, Shaojie Wang, Yan Wei, Xin Xie, Di Huang   +7 more
wiley   +1 more source

A rare case of perineal neuralgia treated with ultrasound‐guided nerve block combined with water separation

Ibrain, Volume 11, Issue 1, Page 106-111, Spring 2025.
A middle‐aged man presented with a right indirect inguinal hernia in November 2020 and underwent laparoscopic high ligation of the right hernial sac. Intermittent acupuncture‐like pain in the skin of the right scrotum and medial thigh occurred 1 month after surgery and lasted for 6 months. Under ultrasound guidance, ilioinguinal nerve and genitofemoral
Yong Wang, Min Wang, Rui Jiang, Zhao‐Qiong Zhu, Guang‐Cai Li   +4 more
wiley   +1 more source

Electrospun encapsulation of grape pomace extract: in vitro antioxidant, anti‐inflammatory, and antihyperglycemic properties

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND The escalating prevalence of lifestyle‐ and aged‐related conditions, including diabetes, chronic inflammation, and cardiovascular disorders, underscores the urgent need for natural therapies. Such alternatives should offer reduced side effects compared to conventional pharmaceuticals while playing a proactive role in disease ...
Estefani Tavares Jansen, Elder Pacheco da Cruz, Laura Martins Fonseca, Marjana Radünz, Taiane Mota Camargo, Alvaro Renato Guerra Dias, Elessandra da Rosa Zavareze   +6 more
wiley   +1 more source