Results 61 to 70 of about 38,088 (249)
CRISPR Toolbox for Genome Editing in Dictyostelium
Frontiers in Cell and Developmental Biology, 2021 The development of new techniques to create gene knockouts and knock-ins is essential for successful investigation of gene functions and elucidation of the causes of diseases and their associated fundamental cellular processes.
Kensuke Yamashita +3 more
doaj +1 more source
The Social Amoeba Dictyostelium discoideum Is Highly Resistant to Polyglutamine Aggregation*
Journal of Biological Chemistry, 2015 Background: The Dictyostelium proteome is predicted to encode a vast amount of homopolymeric amino acid tracts, including long polyglutamine tracts. Results: Proteins with long polyglutamine tracts are soluble in Dictyostelium.
Stephanie Santarriaga +6 more
semanticscholar +1 more source
A recombinant antibody toolbox for Dictyostelium discoideum
BMC Research Notes, 2020 Objective The amoeba Dictyostelium discoideum has been a valuable model organism to study numerous facets of eukaryotic cell biology, such as cell motility, cell adhesion, macropinocytosis and phagocytosis, host–pathogen interactions and multicellular ...
Wanessa C. Lima +2 more
doaj +1 more source
Mechanobiological Dynamics‐Inspired Mechanomodulatory Biomaterials
Advanced Science, Volume 13, Issue 4, 19 January 2026.Recent advances in biomaterial‐mediated mechanomodulation of stem cell fate, encompassing 2, 3, and 4D systems and their synergy with artificial intelligence is overviewed. By integrating knowledge from diverse fields, this review ultimately aims to inspire the design of smarter biomaterial systems that can accelerate the clinical translation of ...
Letao Yang +6 more
wiley +1 more source
Monitoring Autophagy in Dictyostelium
, 2013 Autophagy is an intracellular degradation mechanism essential for cell survival and maintenance of cellular homeostasis, differentiation, and development. Recent research has highlighted the impact of autophagy in neurodegenerative diseases and aging.
Mesquita A +3 more
openaire +4 more sources
An anatomy ontology to represent biological knowledge in
BMC Genomics, 2008 Background Dictyostelium discoideum is a model system for studying many important physiological processes including chemotaxis, phagocytosis, and signal transduction.
Fey Petra +3 more
doaj +1 more source
Aggregate, Volume 7, Issue 1, January 2026.We developed a general tissue‐extraction strategy that directly purifies native F‐actin and actin–tropomyosin–myosin (ATM) complexes from human and rodent muscles for cryo‐EM. Near‐atomic structures, including an HCM R404Q mouse model, reveal how a disease myosin mutation remodels ATM assembly and alters myosin conformation at the actin interface ...
Danni Li +15 more
wiley +1 more source
Triparental inheritance in Dictyostelium [PDF]
Proceedings of the National Academy of Sciences, 2018 Sex promotes the recombination and reassortment of genetic material and is prevalent across eukaryotes, although our knowledge of the molecular details of sexual inheritance is scant in several major lineages. In social amoebae, sex involves a promiscuous mixing of cytoplasm before zygotes consume the majority of cells, but for ...
Gareth Bloomfield +4 more
openaire +2 more sources
Recent Advances in CRISPR/Cas9-Mediated Genome Editing in Dictyostelium
Cells, 2019 In the last 30 years, knockout of target genes via homologous recombination has been widely performed to clarify the physiological functions of proteins in Dictyostelium.
Tetsuya Muramoto +3 more
doaj +1 more source
PLoS ONE, 2020 Cell-substrate adhesion of the social amoeba Dictyostelium discoideum, a model organism often used for the study of chemotaxis, is non-specific and does not involve focal adhesion complexes.
Richa Karmakar +7 more
doaj +1 more source