Results 61 to 70 of about 52,165 (246)
Analysis of Chemotaxis in Dictyostelium [PDF]
Dictyostelium discoideum is an excellent model organism for the study of directed cell migration, since Dictyostelium cells show robust chemotactic responses to the chemoattractant cAMP. Many powerful experimental tools are applicable, including forward and reverse genetics, biochemistry, microscopy, and proteomics.
Chuan Hsiang Huang+3 more
openaire +3 more sources
Origin and evolution of the slime molds (Mycetozoa) [PDF]
The Mycetozoa include the cellular (dictyostelid), acellular (myxogastrid), and protostelid slime molds. However, available molecular data are in disagreement on both the monophyly and phylogenetic position of the group.
Baldauf, S.L., Doolittle, W.F.
core +2 more sources
Protein tandem repeats that produce frameshifts can generate new structural states and functions
We explored an alternative protein structure landscape by analyzing amino acid sequences from frameshifted tandem repeats—regions prone to frameshifts. These frameshifts, especially in short repeats, lead to more drastic changes than in non‐repetitive regions, often altering structure, function, localization, and potentially contributing to disease ...
Zarifa Osmanli+8 more
wiley +1 more source
CRISPR Toolbox for Genome Editing in Dictyostelium
The development of new techniques to create gene knockouts and knock-ins is essential for successful investigation of gene functions and elucidation of the causes of diseases and their associated fundamental cellular processes.
Kensuke Yamashita+3 more
doaj +1 more source
Statistical Modelling of Cell Movement [PDF]
In this paper we demonstrate an application of the unscented Kalman filter in the context of cell movement, using a model defined in terms of stochastic differential equations (SDEs)
Giurghita, Diana, Husmeier, Dirk
core +2 more sources
The morphodynamical plasticity of the endolysosomal system supports the formation and function of specialized intracellular compartments, as exemplified by the pigment organelles in skin cells. In epidermal melanocytes and keratinocytes, membrane trafficking and remodeling coordinate tissue pigmentation and protect the genome from photodamage ...
Laura Salavessa+4 more
wiley +1 more source
Dictyostelium cells are forest soil amoebae, which feed on bacteria and proliferate as solitary cells until bacteria are consumed. Starvation triggers a change in life style, forcing cells to gather into aggregates to form multicellular organisms ...
Salvatore eBozzaro+2 more
doaj +1 more source
A recombinant antibody toolbox for Dictyostelium discoideum
Objective The amoeba Dictyostelium discoideum has been a valuable model organism to study numerous facets of eukaryotic cell biology, such as cell motility, cell adhesion, macropinocytosis and phagocytosis, host–pathogen interactions and multicellular ...
Wanessa C. Lima+2 more
doaj +1 more source
Stereochemically defined inositol pyrophosphate isomers (PP‐InsP4) were synthesized and assigned by NMR spectroscopy using a chiral solvating reagent. In the form of isotopically labeled standards, they were applied in CE‐MS‐based profiling of plant extracts and kinase assays, enabling structural reassignment and functional insight into enzymatic ...
Kevin Ritter+6 more
wiley +1 more source
Chromatin Structure in the Cellular Slime Mold Dictyostelium discoideum [PDF]
The structure of Dictyostelium discoideum chromatin has been studied by the following techniques: electron microscopy, staphylococcal nuclease digestion, acrylamide gel electrophoresis, sucrose gradient centrifugation, and melting.
Bakke, Antony C.+2 more
core