Results 101 to 110 of about 47,596 (285)

The Parkinson's disease-associated protein DJ-1 plays a positive nonmitochondrial role in endocytosis in Dictyostelium cells

Disease Models & Mechanisms, 2017
The loss of function of DJ-1 caused by mutations in DJ1 causes a form of familial Parkinson's disease (PD). However, the role of DJ-1 in healthy and in PD cells is poorly understood. Even its subcellular localization in mammalian cells is uncertain, with
Suwei Chen, Sarah J. Annesley, Rasha A. F. Jasim, Vanessa J. Musco, Oana Sanislav, Paul R. Fisher   +5 more
doaj   +1 more source

Amino acid repeats cause extraordinary coding sequence variation in the social amoeba Dictyostelium discoideum. [PDF]

PLoS ONE, 2012
Protein sequences are normally the most conserved elements of genomes owing to purifying selection to maintain their functions. We document an extraordinary amount of within-species protein sequence variation in the model eukaryote Dictyostelium ...
Clea Scala, Xiangjun Tian, Natasha J Mehdiabadi, Margaret H Smith, Gerda Saxer, Katie Stephens, Prince Buzombo, Joan E Strassmann, David C Queller   +8 more
doaj   +1 more source

Fruiting bodies of the social amoeba Dictyostelium discoideum increase spore transport by Drosophila

BMC Evolutionary Biology, 2014
BackgroundMany microbial phenotypes are the product of cooperative interactions among cells, but their putative fitness benefits are often not well understood.
Jeff Smith, D. Queller, J. Strassmann
semanticscholar   +1 more source

Perspective on Interdisciplinary Approaches on Chemotaxis

Angewandte Chemie International Edition, Volume 64, Issue 47, November 17, 2025.
Chemotaxis is the movement of individual organisms towards or away from a chemical stimulus. This phenomenon is investigated in various disciplines, ranging from biology to physics and even engineering. This perspective aims to summarise recent developments in the field and encourage the unification of terminology to promote interdisciplinary knowledge
Juliane Simmchen, Daniel Gordon, John MacKenzie, Ignacio Pagonabarraga, Christina C. Roggatz, Robert G. Endres, Zuyao Xiao, Benjamin M. Friedrich, Tian Qiu, Kevin J. Painter, Ramin Golestanian, Claudia Contini, Mehmet Can Ucar, Gilad Yossifon, Jens Uwe Sommer, Wouter‐Jan Rappel, Kirsty Y. Wan, Judith Armitage, Robert Insall   +18 more
wiley   +1 more source

Fate and regulation of anterior-like cells in Dictyostelium slugs [PDF]

, 1982
A pattern of two tissue types exists in the Dictyostelium slug. Contained within the posterior tissue are anterior-like cells which comprise about 10% of the developing cell mass.
David, Charles N., Sternfeld, John
core   +1 more source

Interactions Between Active Matters and Endogenous Fields

Advanced Materials, Volume 37, Issue 45, November 13, 2025.
This review synthesizes endogenous field information and computational methods in contexts such as cancer, wounds, and biofilms. It organizes NAMs and AAMs by sensing, transmitting, and executing functions, compares their limitations, and from these contrasts proposes design strategies for next‐generation AAMs, offering perspectives to foster ...
Jinwei Lin, Qiaoxin Guan, Jiangqi Feng, Shuqin Chen, Leilei Xu, Jianguo Guan, Samuel Sánchez   +6 more
wiley   +1 more source

cAMP activates adenylate and guanylate cyclase of Dictyostelium discoideum cells by binding to different classes of cell-surface receptors. A study with extracellular Ca2+ [PDF]

, 1985
cAMP induces a transient increase of cAMP and cGMP levels in Dictyostelium discoideum cells. Fast binding experiments reveal three types of cAMP-binding site (S, H and L), which have different off-rates (t0.5, 0.7-15 s) and different affinities (Kd, 15 ...
Brachet, Bumann, De Wit, Devreotes, Dinauer, Gerisch, Gerisch, Janssens, Juliani, Kay, Konijn, Leichtling, Marin, Mato, Pannbacker, Roos, Schaap, Shaffer, Stadel, Toews, Van Haastert, Van Haastert, Van Haastert, Van Haastert, Van Haastert, Van Haastert   +25 more
core   +3 more sources

The Elmo family forms an ancient group of actin-regulating proteins

Communicative & Integrative Biology, 2009
The Elmo protein family members are important mediators of small G protein activity, regulating actin-mediated processes such as chemotaxis and engulfment.
Joseph A. Brzostowski, Petra Fey, Jianshe Yan, Nilgun Isik, Tian Jin   +4 more
doaj   +1 more source

A Dictyostelium discoideum mitochondrial fluorescent tagging vector that does not affect respiratory function

Biochemistry and Biophysics Reports, 2020
Visualizing mitochondria in living Dictyostelium discoideum cells using fluorescent dyes is often problematic due to variability in staining, metabolism of the dyes, and unknown potential effects of the dyes on mitochondrial function.
Christopher J. Perry, Eleanor C. Warren, Joseph L. Damstra-Oddy, Claire Storey, Lisa M. Francione, Sarah J. Annesley, Paul R. Fisher, Annette Müller-Taubenberger, Robin S.B. Williams   +8 more
doaj   +1 more source

Initiation of multicellular differentiation in Dictyostelium discoideum is regulated by coronin A

Molecular Biology of the Cell, 2014
Multicellular development of Dictyostelium is induced by starvation and is crucial for its long-term survival. Coronin A mediates the transition from growth to development of the cells and initiates the cAMP-dependent relay by regulating the response to ...
Adrien F. Vinet, T. Fiedler, V. Studer, R. Froquet, A. Dardel, P. Cosson, J. Pieters   +6 more
semanticscholar   +1 more source