Results 91 to 100 of about 41,925 (254)
FEBS Open Bio, Volume 16, Issue 2, Page 268-278, February 2026.IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić +3 more
wiley +1 more source
Biochemistry and Biophysics Reports, 2020 Visualizing mitochondria in living Dictyostelium discoideum cells using fluorescent dyes is often problematic due to variability in staining, metabolism of the dyes, and unknown potential effects of the dyes on mitochondrial function.
Christopher J. Perry +8 more
doaj +1 more source
Highlights of the FEBS3+ meeting Exploring molecular frontiers
FEBS Open Bio, Volume 16, Issue 2, Page 240-242, February 2026.FEBS+ meeting Exploring molecular frontiers, held in Pula, Croatia, in autumn 2024 was jointly organized by the Croatian, Finnish, and Swedish Member Societies of the Federation of European Biochemical Societies (FEBS). The congress covered a wide variety of different biochemical themes, some of the highlights of which are presented in this ‘In the ...
Morana Dulić +2 more
wiley +1 more source
An anatomy ontology to represent biological knowledge in
BMC Genomics, 2008 Background Dictyostelium discoideum is a model system for studying many important physiological processes including chemotaxis, phagocytosis, and signal transduction.
Fey Petra +3 more
doaj +1 more source
Amino acid repeats cause extraordinary coding sequence variation in the social amoeba Dictyostelium discoideum. [PDF]
PLoS ONE, 2012 Protein sequences are normally the most conserved elements of genomes owing to purifying selection to maintain their functions. We document an extraordinary amount of within-species protein sequence variation in the model eukaryote Dictyostelium ...
Clea Scala +8 more
doaj +1 more source
PLoS ONE, 2012 Spontaneous mutations play a central role in evolution. Despite their importance, mutation rates are some of the most elusive parameters to measure in evolutionary biology.
G. Saxer +7 more
semanticscholar +1 more source
Protein tandem repeats that produce frameshifts can generate new structural states and functions
The FEBS Journal, Volume 293, Issue 3, Page 842-858, February 2026.We explored an alternative protein structure landscape by analyzing amino acid sequences from frameshifted tandem repeats—regions prone to frameshifts. These frameshifts, especially in short repeats, lead to more drastic changes than in non‐repetitive regions, often altering structure, function, localization, and potentially contributing to disease ...
Zarifa Osmanli +8 more
wiley +1 more source
Microbiology SpectrumAmong sequenced organisms, the genome of Dictyostelium discoideum is unique in that it encodes for a massive amount of repeat-rich sequences in the coding region of genes.
Felicia N. Williams +5 more
doaj +1 more source
Disease Models & Mechanisms, 2017 The loss of function of DJ-1 caused by mutations in DJ1 causes a form of familial Parkinson's disease (PD). However, the role of DJ-1 in healthy and in PD cells is poorly understood. Even its subcellular localization in mammalian cells is uncertain, with
Suwei Chen +5 more
doaj +1 more source
CHROMOSOME REARRANGEMENTS IN DICTYOSTELIUM DISCOIDEUM [PDF]
Genetics, 1982 ABSTRACT A tandem duplication (D350(III,III)) of the whiB to radB interval of linkage group III has been characterized. The gene order on the duplication-bearing chromosome is: centromere, whiB500, radB+, whiB+, radB24, bsgA5, acrC4. Slow-growing, duplication-bearing strains (yellow-spored, radiation-resistant) produced four classes of ...
D L, Welker, B A, Metz, K L, Williams
openaire +2 more sources