Results 101 to 110 of about 41,925 (254)
Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita +3 more
wiley +1 more source
Cell migration directionality and speed are independently regulated by RasG and Gβ in Dictyostelium cells in electrotaxis. [PDF]
Motile cells manifest increased migration speed and directionality in gradients of stimuli, including chemoattractants, electrical potential and substratum stiffness.
Devreotes, Peter N +6 more
core
Measuring cell adhesion forces with the atomic force microscope at the molecular level [PDF]
In the past 25 years many techniques have been developed to characterize cell adhesion and to quantify adhesion forces. Atomic force microscopy (AFM) has been used to measure forces in the pico-newton range, an experimental technique known as force ...
Benoit, M., Gaub, H. E.
core +1 more source
We developed a general tissue‐extraction strategy that directly purifies native F‐actin and actin–tropomyosin–myosin (ATM) complexes from human and rodent muscles for cryo‐EM. Near‐atomic structures, including an HCM R404Q mouse model, reveal how a disease myosin mutation remodels ATM assembly and alters myosin conformation at the actin interface ...
Danni Li +15 more
wiley +1 more source
Multiarmed Spirals in Excitable Media [PDF]
Numerical studies of the properties of multiarmed spirals show that they can form spontaneously in low excitability media. The maximum number of arms in a multiarmed spiral is proportional to the ratio of the single spiral period to the refractoriness of
Siegert, Florian +2 more
core +1 more source
Developmental decisions in Dictyostelium discoideum
A few hours after the onset of starvation, amoebae of Dictyostelium discoideum start to form multicellular aggregates by chemotaxis to centers that emit periodic cyclic AMP signals. There are two major developmental decisions: first, the aggregates either construct fruiting bodies directly, in a process known as culmination, or they migrate for a ...
openaire +2 more sources
A New Classification Framework to Understand Evolutionary Transitions in Individuality
Classifying biological entities based on whether and how the two fundamental aspects physiological and evolutionary components are represented yields six types of structural organization. The resulting framework allows to compare different forms of organization, and, in this way, provides insight into the evolutionary processes giving rise to these ...
Saskia Wilmsen, Christian Kost
wiley +1 more source
Conditional expression explains molecular evolution of social genes in a microbe
Genetic diversity in social genes is expected to be shaped by conflict. Here, the authors show that in Dictyostelium discoideum, social genes in fact exhibit diversification patterns consistent with relaxed purifying selection, likely due to their ...
Janaina Lima de Oliveira +10 more
doaj +1 more source
Dictyostelium discoideum microvesicles have recently been presented as a valuable model for eukaryotic extracellular vesicles. Here, the advantages of D.
Irène Tatischeff
doaj +1 more source
Abstract Avian eggshell membrane (ESM) is fabricated within the isthmus region of the oviduct and is comprised of three juxtaposed, predominantly proteinaceous layers lying between egg white and the calcified shell. The limiting membrane is less than 0.5 μm in thickness and forms the osmotic barrier for the egg. This first layer provides the foundation
Somayeh Zeinalilathori +6 more
wiley +1 more source

