Dynamical strategies for obstacle avoidance during Dictyostelium discoideum aggregation: a Multi-agent system model [PDF]
Chemotaxis, the movement of an organism in response to chemical stimuli, is a typical feature of many microbiological systems. In particular, the social amoeba \textit{Disctyostelium discoideum} is widely used as a model organism, but it is not still ...
Maggiora, Marco, Proverbio, Daniele
core +1 more source
Efficient generation of gene knockout plasmids for Dictyostelium discoideum using one-step cloning.
The amoeba Dictyostelium discoideum is a well-established model organism for studying numerous aspects of cellular and developmental functions. Its rather small (~34Mb) chromosomal genome and the high efficiency of gene disruption by homologous ...
Stephan Wiegand +3 more
semanticscholar +1 more source
Developmental decisions in Dictyostelium discoideum
Dictyostelium discoideum is an excellent system in which to study developmental decisions. Synchronous development is triggered by starvation and rapidly generates a limited number of cell types. Genetic and image analyses have revealed the elegant intricacies associated with this simple development system.
Strmecki, L, Greene, D, Pears, C
openaire +3 more sources
Eine Perspektive zu interdisziplinären Ansätzen in der Chemotaxis(forschung)
Chemotaxis ist die Bewegung individueller Agenten hin zu oder weg von einem chemischen Stimulus. Dieses Phänomen wird in den verschiedensten Fachbereichen untersucht, von Biologie hin zu Physik und auch im Ingenieurwesen. Dieses Perspektivpapier zielt darauf ab, neue Entwicklungen im Feld darzustellen und die Vereinheitlichung von Terminologie zu ...
Juliane Simmchen +18 more
wiley +1 more source
ABC Transporters in Dictyostelium discoideum Development
ATP-binding cassette (ABC) transporters can translocate a broad spectrum of molecules across the cell membrane including physiological cargo and toxins. ABC transporters are known for the role they play in resistance towards anticancer agents in chemotherapy of cancer patients.
Miranda, Edward Roshan +6 more
openaire +6 more sources
Perspective on Interdisciplinary Approaches on Chemotaxis
Chemotaxis is the movement of individual organisms towards or away from a chemical stimulus. This phenomenon is investigated in various disciplines, ranging from biology to physics and even engineering. This perspective aims to summarise recent developments in the field and encourage the unification of terminology to promote interdisciplinary knowledge
Juliane Simmchen +18 more
wiley +1 more source
Multiscale modeling of oscillations and spiral waves in Dictyostelium populations
Unicellular organisms exhibit elaborate collective behaviors in response to environmental cues. These behaviors are controlled by complex biochemical networks within individual cells and coordinated through cell-to-cell communication.
Gregor, Thomas +4 more
core +1 more source
Comparative genomics of the social amoebae Dictyostelium discoideum and Dictyostelium purpureum
BackgroundThe social amoebae (Dictyostelia) are a diverse group of Amoebozoa that achieve multicellularity by aggregation and undergo morphogenesis into fruiting bodies with terminally differentiated spores and stalk cells.
R. Sucgang +40 more
semanticscholar +1 more source
Deficiency of Huntingtin Has Pleiotropic Effects in the Social Amoeba Dictyostelium discoideum
Huntingtin is a large HEAT repeat protein first identified in humans, where a polyglutamine tract expansion near the amino terminus causes a gain-of-function mechanism that leads to selective neuronal loss in Huntington's disease (HD).
Michael A. Myre +5 more
semanticscholar +1 more source
The Professional Phagocyte Dictyostelium discoideum as a Model Host for Bacterial Pathogens
The use of simple hosts such as Dictyostelium discoideum in the study of host pathogen interactions offers a number of advantages and has steadily increased in recent years.
S. Bozzaro, L. Eichinger
semanticscholar +1 more source

