Results 51 to 60 of about 47,596 (285)
PLoS Genetics, 2009 Organisms like Dictyostelium discoideum, often referred to as DNA damage "extremophiles", can survive exposure to extremely high doses of radiation and DNA crosslinking agents. These agents form highly toxic DNA crosslinks that cause extensive DNA damage.
Xiao-Yin Zhang +5 more
doaj +1 more source
The dictyostelium kinome--analysis of the protein kinases from a simple model organism. [PDF]
PLoS Genetics, 2006 Dictyostelium discoideum is a widely studied model organism with both unicellular and multicellular forms in its developmental cycle. The Dictyostelium genome encodes 285 predicted protein kinases, similar to the count of the much more advanced ...
Jonathan M Goldberg +6 more
doaj +2 more sources
Role of bacterial surface structures on the interaction of Klebsiella pneumoniae with phagocytes. [PDF]
PLoS ONE, 2013 Phagocytosis is a key process of the immune system. The human pathogen Klebsiella pneumoniae is a well known example of a pathogen highly resistant to phagocytosis.
Catalina March +8 more
doaj +1 more source
The endocytic pathways of Dictyostelium discoideum.
International Journal of Developmental Biology, 2019 The formation and processing of vesicles from the cell surface serves many important cellular functions ranging from nutrient acquisition to regulating the turnover of membrane components and signalling.
James H Vines, J. King
semanticscholar +1 more source
Dictyostelium discoideum transformation by oscillating electric field electroporation
BioTechniques, 2003 Dictyostelium discoideum has been used as a genetically tractable model organism to study many biological phenomena. High-efficiency transformation is a prerequisite for successful genetic screens such as mutant complementation, identification of ...
Laeticia Alibaud +2 more
doaj +1 more source
Unraveling Adaptation in Eukaryotic Pathways: Lessons from Protocells [PDF]
, 2013 Eukaryotic adaptation pathways operate within wide-ranging environmental conditions without stimulus saturation. Despite numerous differences in the adaptation mechanisms employed by bacteria and eukaryotes, all require energy consumption.
De Palo, Giovanna, Endres, Robert G.
core +4 more sources
Evolution of size and pattern in the social amoebas [PDF]
, 2007 A fundamental goal of biology is to understand how novel phenotypes evolved through changes in existing genes. The Dictyostelia or social amoebas represent a simple form of multicellularity, where starving cells aggregate to build fruiting structures ...
Schaap, P.
core +4 more sources
Frontiers in Microbiology, 2016 The social amoeba Dictyostelium discoideum has proven to be a useful model for studying relevant aspects of the host-pathogen interaction. In this work, D.
S. Riquelme +10 more
semanticscholar +1 more source
The role of the cortical cytoskeleton [PDF]
, 1996 We generated Dictyostelium double mutants lacking the two F-actin crosslinking proteins alpha-actinin and gelation factor by inactivating the corresponding genes via homologous recombination.
Albrecht, Richard +8 more
core +1 more source
Msphere, 2016 The genetic factors used for host interaction by the opportunistic human pathogen Pantoea ananatis are largely unknown. We identified two genes that are important for the production of a biosurfactant that confers grazing resistance against the social ...
D. Smith +3 more
semanticscholar +1 more source