Results 71 to 80 of about 46,917 (300)
Electrophoretic karyotype for Dictyostelium discoideum. [PDF]
Proceedings of the National Academy of Sciences, 1990 This paper reports on the separation of the Dictyostelium discoideum chromosomes by pulse-field electrophoresis and the correlation of the electrophoretic pattern with linkage groups established by classical genetic methods. In two commonly used laboratory strains, five chromosome-sized DNA molecules have been identified.
Edward C. Cox +4 more
openaire +3 more sources
The Social Amoeba Dictyostelium discoideum Is Highly Resistant to Polyglutamine Aggregation*
Journal of Biological Chemistry, 2015 Background: The Dictyostelium proteome is predicted to encode a vast amount of homopolymeric amino acid tracts, including long polyglutamine tracts. Results: Proteins with long polyglutamine tracts are soluble in Dictyostelium.
Stephanie Santarriaga +6 more
semanticscholar +1 more source
A signal transduction blind spot: the function of adenylyl cyclase transmembrane domains
The FEBS Journal, EarlyView.Transmembrane adenylyl cyclases (tmACs) are essential for synthesising the universal second messenger cyclic AMP. All tmACs share a common topology that includes a large 12‐helix transmembrane (TM) domain. This domain accounts for ~ 35% of the coding sequence but its function is still an open question.
Ryan S. Dowsell, Matthew G. Gold
wiley +1 more source
Dictyostelium: An Important Source of Structural and Functional Diversity in Drug Discovery
Cells, 2018 The cellular slime mold Dictyostelium discoideum is an excellent model organism for the study of cell and developmental biology because of its simple life cycle and ease of use.
Yuzuru Kubohara, Haruhisa Kikuchi
doaj +1 more source
DEPENDENCE OF CELL-TYPE PROPORTIONING AND SORTING ON CELL CYCLE PHASE IN DICTYOSTELIUM DISCOIDEUM [PDF]
, 1984 The relationship between the cell cycle phase of vegetative amoebae and prestalk and prespore differentiation in the slug stage were investigated in the slime mould Dictyostelium discoideum.
David, Charles N. +2 more
core
Motility mutants of Dictyostelium discoideum. [PDF]
The Journal of cell biology, 1982 We describe six motility mutants of Dictyostelium discoideum in this report. They were identified among a group of temperature-sensitive growth (Tsg) mutants that had been previously isolated using an enrichment for phagocytosis-defective cells. The Tsg mutants were screened for their ability to produce tracks on gold-coated cover slips, and several ...
Martin Reichel, S C Kayman, M Clarke
openaire +3 more sources
PLoS ONE, 2014 The neuronal ceroid lipofuscinoses (NCL) are a group of inherited, severe neurodegenerative disorders also known as Batten disease. Juvenile NCL (JNCL) is caused by recessive loss-of-function mutations in CLN3, which encodes a transmembrane protein that ...
R. Huber, Michael A. Myre, S. Cotman
semanticscholar +1 more source
Luminal Phospholipase D Attacks Bacterial Membranes in Dictyostelium discoideum Phagosomes
Molecular Microbiology, EarlyView.This study shows that PldX, a luminal Phospholipase D, is necessary for the efficient destruction of ingested Klebsiella pneumoniae bacteria in Dictyostelium discoideum phagosomes. PldX and the AlyL lysozyme together attack the bacterial membrane and permeabilize it. To date, the molecular substrate of PldX remains to be determined. ABSTRACT Phagocytic
Otmane Lamrabet +6 more
wiley +1 more source
Mathematical models for chemotaxis and their applications in self-organisation phenomena [PDF]
, 2018 Chemotaxis is a fundamental guidance mechanism of cells and organisms, responsible for attracting microbes to food, embryonic cells into developing tissues, immune cells to infection sites, animals towards potential mates, and mathematicians into biology.
Painter, K. J.
core +3 more sources
Spore germination in Dictyostelium discoideum. [PDF]
Proceedings of the National Academy of Sciences, 1966 Mutant spores of Dictyostelium discoideum, strain SG-10, differ from wild type spores in their ability to spontaneously germinate, to be activated with 5% dimethyl Sulfoxide (DMSO), and to be deactivated with 0.2 M sucrose. Both heat-activated wild type and mutant spores began to swell after a lag of 60–75 min at ambient temperature. Suspension of heat
D A Cotter, K B Raper
openaire +3 more sources