Results 101 to 110 of about 1,252,753 (304)

Fucoxanthinol, Metabolite of Fucoxanthin, Improves Obesity-Induced Inflammation in Adipocyte Cells

Marine Drugs, 2015
Fucoxanthin (Fx) is a marine carotenoid found in edible brown seaweeds. We previously reported that dietary Fx metabolite into fucoxanthinol (FxOH), attenuates the weight gain of white adipose tissue of diabetic/obese KK-Ay mice.
Hayato Maeda, Shogo Kanno, Mei Kodate, Masashi Hosokawa, Kazuo Miyashita   +4 more
doaj   +1 more source

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

FAKTOR YANG BERHUBUNGAN DENGAN HAMBATAN DIET DIABETES MELLITUS PADA PASIEN DIABETES MELLITUS TIPE 2 DI WILAYAH KERJA PUSKESMAS WONOSARI KABUPATEN BONDOWOSO

Jurnal Ilmu Kesehatan Masyarakat, 2013
Diabetes mellitus type 2 (DM type 2) is chronic disease that needed long term treatment. Diet plays an important role in the management of diabetes, and a suboptimal diet is a commonly identified problem.
R Rondhianto
doaj  

Gut Microbiota‐Derived Indole‐3‐Propionic Acid Alleviates Diabetic Osteoporosis Through Nrf2‐Mediated Ferroptosis Suppression

Advanced Science, EarlyView.
Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai, Qinyong You, Gao Si, Daole Hu, Ao Sun, Shilong Su, Ruideng Wang, Jixing Fan, Shan Gao, Tengjiao Zhu, Chun‐Li Song, Fang Zhou, Yang Lv   +12 more
wiley   +1 more source

PENGARUH DIET KACANG MERAH TERHADAP KADAR GULA DARAH TIKUS DIABETIK INDUKSI ALLOXAN [Effect of Red Bean Diet on Blood Glucose Concentration of Alloxan-Induced Diabetic Rats]

Jurnal Teknologi dan Industri Pangan, 2003
Hypoglycemic response of red bean were evaluated in alloxan-induced diabetic rats. The objective of this research was to evaluate the effect of red bean (Vigna umbellata) diet compare with soy bean diet on blood glucose concentration in alloxan-induced ...
Y. Marsono 1), Zuheid Noor 1), Fitri Rahmawati 2)   +2 more
doaj  

Prevalence of diabetic retinopathy at Parirenyatwa hospital

, 2019
BACKGROUND: There is a global epidemic of diabetes mellitus. Diabetes mellitus causes a myriad of microvascular and macrovascular complications. Diabetic retinopathy is one of the main microvascular complications. It is preventable.
Maboreke, Nyasha Phanuel
core  

Antihyperglycemic and antidyslipidemic activity of Musa paradisiaca‐based diet in alloxan‐induced diabetic rats

, 2017
This study was aimed at investigating the antihyperglycemic and antidyslipidemic activity of Musa paradisiaca‐based diets in alloxan‐induced diabetic mellitus rats.
Ajiboye, Basiru O., Basiru O. Ajiboye, Salawu, Musa O., Musa O. Salawu, Oloyede, Hussein O. B., Hussein O. B. Oloyede   +5 more
core   +1 more source

Sex‐ and Time‐Resolved Physiological and Gut Ecosystem Responses to a Food‐Grade Microbiome‐Targeted Intervention in Collegiate Endurance Athletes

Advanced Science, EarlyView.
In collegiate endurance athletes, a 6‐week randomized CPYE intervention yielded time‐ and sex‐dependent shifts in field‐based cardiorespiratory, metabolic, and redox indices, accompanied by changes in gut multi‐omics profiles. An exploratory extension during intensified training generates hypotheses warranting future validation.
Meng Zhang, Le Ge, Kaiyang Liu, Yanrong Liu, Guolin Zhao, Lai‐Yu Kwok, Zheng Sun, Zhihong Sun, Wenyi Zhang   +8 more
wiley   +1 more source

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

Advanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi, Qiang Zhao, Yue Lve, Yaming Yuan, Tingting Zhou, Yue Yuan, Dexi Wu, Yifan Tang, Yan Liu, Zhigang Li, Chunping Jiang, Qiurong Ding   +11 more
wiley   +1 more source

PENGARUH FRAKSI NONPROTEIN KACANG KOMAK (Lablab purpureus (L.) Sweet) TERHADAP KADAR GLUKOSA DARAH DAN MALONALDEHIDA TIKUS DIABETES [Effect of Nonprotein Fraction of Hyacinth Bean (Lablab purpureus (L.) Sweet) Diet on Glucose and Malonaldehyde Serum of

Jurnal Teknologi dan Industri Pangan, 2010
The hypoglycemic response to Lablab nonprotein fraction (NPK) was evaluated in alloxan-induced diabetic rats. The objectives of this research were to evaluate the effect of Lablab nonprotein fraction diet on the blood  glucose concentration and the ...
Arif Hartoyo, Sukarno ., Erma Rohmawati
doaj