Results 31 to 40 of about 84,808 (235)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Effect of diet with or without exercise on abdominal fat in postmenopausal women – a randomised trial

open access: yesBMC Public Health, 2019
Background We assessed the effect of equivalent weight loss with or without exercise on (intra-) abdominal fat in postmenopausal women in the SHAPE-2 study.
Willemijn A. van Gemert   +9 more
doaj   +1 more source

TRAILS TO IMPROVE GROWTH AND CARCASS QUALITY IN DUCK [PDF]

open access: yesKafrelsheikh Veterinary Medical Journal, 2009
Reducing fat in duck lean is consider the first step towards improvingcarcass quality. A total of 144 male and female, one day old whitePeking ducks were divided into 6 equal groups, each group subdividedinto 2 subgroup.
O Sakr, K. Gaffar, S M. Hegazi
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Low fat-diet and circulating adipokines concentrations: a systematic review and meta-analysis of randomized controlled trials

open access: yesDiabetology & Metabolic Syndrome
Background Low-fat diets have gained considerable attention in the management of obesity. The present meta-analysis evaluated randomized controlled trials (RCTs) to determine whether adults adhering to low-fat diets (≤ 30% of total energy intake ...
Sepideh Soltani   +8 more
doaj   +1 more source

The calorically restricted ketogenic diet, an effective alternative therapy for malignant brain cancer

open access: yesNutrition & Metabolism, 2007
Background Malignant brain cancer persists as a major disease of morbidity and mortality in adults and is the second leading cause of cancer death in children. Many current therapies for malignant brain tumors fail to provide long-term management because
Zhou Weihua   +5 more
doaj   +1 more source

Effect of toxic trace element detoxification, body fat reduction following four-week intake of the Wellnessup diet: a three-arm, randomized clinical trial

open access: yesNutrition & Metabolism, 2020
Background Detox diet are known as a popular dieting strategies that helps toxins elimination and weight manage but there is very little clinical evidence.
Su-Jin Jung   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Changes in gene expression foreshadow diet-induced obesity in genetically identical mice.

open access: yesPLoS Genetics, 2006
High phenotypic variation in diet-induced obesity in male C57BL/6J inbred mice suggests a molecular model to investigate non-genetic mechanisms of obesity. Feeding mice a high-fat diet beginning at 8 wk of age resulted in a 4-fold difference in adiposity.
Robert A Koza   +7 more
doaj   +2 more sources

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