Results 51 to 60 of about 1,943,434 (254)

Dietary restriction, caloric value and the accumulation of hepatic fat

Lipids in Health and Disease, 2012
Background Studies using laboratory animals under what are considered to be "standard" conditions normally offer unrestricted amounts of food to the animals, which can lead to metabolic disorders. Moreover, standard diets have different compositions. Aim
Moura Leandro P, Figueredo Gabriella A, Bertolini Natália O, Ceccato Marilia, Pereira Jessica R, Sponton Amanda Christine S, de Mello Maria Alice R   +6 more
doaj   +1 more source

A fifty percent leucine-restricted diet reduces fat mass and improves glucose regulation

Nutrition & Metabolism, 2021
Background Leucine deprivation modulates the dietary amino acid composition, reducing the fat content and improving the glucose tolerance, thus protecting the organism against obesity.
Ziheng Zhou, Hanrui Yin, Yajie Guo, Yuanyuan Fang, Feixiang Yuan, Shanghai Chen, Feifan Guo   +6 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Vascular dysfunction induced in offspring by maternal dietary fat involves altered arterial polyunsaturated fatty acid biosynthesis

, 2012
Nutrition during development affects risk of future cardiovascular disease. Relatively little is known about whether the amount and type of fat in the maternal diet affect vascular function in the offspring.
Masoodi, Mojgan, Geraldine F Clough, Karen A Lillycrop, Samuel P Hoile, Karen A. Lillycrop, Irvine, Nicola A., Philip C. Calder, Graham C. Burdge, Kelsall, Christopher J., Christopher Torrens (114420), Geraldine F. Clough, Geraldine F. Clough (114433), Christopher J. Kelsall, Lillycrop, Karen A., Calder, Philip C., Mojgan Masoodi (152735), Mark A. Hanson (114427), Hoile, Samuel P., Burdge, Graham C., Christopher J. Kelsall (173702), Mark A Hanson, Christopher J Kelsall, Graham C Burdge, Nicola A. Irvine (173711), Torrens, Christopher, Samuel P. Hoile, Nicola A Irvine, Graham C. Burdge (173729), Philip C Calder, Mojgan Masoodi, Hanson, Mark A., Philip C. Calder (173723), Christopher Torrens, Nicola A. Irvine, Clough, Geraldine F., Mark A. Hanson, Samuel P. Hoile (173705), Karen A. Lillycrop (173718)   +37 more
core   +1 more source

Effects of oil and natural or synthetic vitamin E on ruminal and milk fatty acid profiles in cows receiving a high-starch diet [PDF]

, 2012
Among trans fatty acids, trans-10,cis-12 CLA has negative effects on cow milk fat production and can affect human health. In high-yielding dairy cows, a shift from the trans-11 to the trans-10 pathway of biohydrogenation (BH) can occur in the rumen of ...
Troegeler-Meynadier, Annabelle, Najar, Taha, Zened, Asma, Enjalbert, Francis   +3 more
core   +1 more source

Effects of Antioxidants Supplemment, Astaxanthin, Vitamin E, C, in Rat Fed a High-Fat Diet

Armaghane Danesh Bimonthly Journal, 2010
Introduction & Objective: obesity is independently associated with increased oxidative stress in men and women. Natural antioxidants showed substantial antioxidative and anti-inflammatory activities in vivo.
AA Vahidinia, R Shakerhossini, H Mahjub
doaj  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Data_Sheet_1_Alteration and the Function of Intestinal Microbiota in High-Fat-Diet- or Genetics-Induced Lipid Accumulation.docx

, 2021
Diet and host genetics influence the composition of intestinal microbiota, yet few studies have compared the function of intestinal microbiota in the diet- or genotype-induced lipid deposition, which limits our understanding of the role of intestinal ...
Fang Tan (353838), Liqiao Chen (322720), Zhen-Yu Du (350261), Mei-Ling Zhang (765444), Ling-Yu Li (4922107), Fang Qiao (805531), Hong-Bo Lv (11447980)   +6 more
core   +1 more source