Results 181 to 190 of about 835,658 (290)

CNPY2 Aggravates Renal Tubular Cell Ferroptosis in Diabetic Nephropathy by Regulating PERK/ATF4/CHAC1 Pathway and MAM Integrity

Advanced Science, EarlyView.
Canopy FGF signaling regulator 2 (CNPY2) which is contributed to ERS is upregulated in the renal tubules of patients with diabetic nephropathy (DN). Mechanistically, CNPY2 may regulate ferroptosis and MAM integrity in renal tubular epithelial cells through PERK/ATF4/CHAC1 pathway, thereby promoting the progression of DN.
Jingfang Chen, Dongwei Liu, Lei Lei, Ting Liu, Shaokang Pan, Hui Wang, Yong Liu, Yingjin Qiao, Zhangsuo Liu, Qi Feng   +9 more
wiley   +1 more source

Dietary Interventions and Oral Nutritional Supplementation in Inflammatory Bowel Disease: Current Evidence and Future Directions. [PDF]

Nutrients
Barberio B, Bertin L, Facchin S, Bonazzi E, Cusano S, Romanelli G, Pesenti FF, Cazzaniga E, Palestini P, Zingone F, Savarino EV.   +10 more
europepmc   +1 more source

Gelsolin's Protective Role in MASH through F‐Actin Regulation and P53 Degradation

Advanced Science, EarlyView.
Gelsolin (GSN) maintains liver metabolic homeostasis by promoting MDM2‐mediated P53 degradation and inhibiting F‐actin/Yes‐associated protein (YAP) overactivation. Loss of GSN impairs P53 degradation, increases lipid deposition, and enhances YAP‐driven fibrosis and inflammation in metabolic‐associated steatohepatitis.
Yiwei Lu, Tong Ji, Zhichao Ye, Jianing Yan, Chao Wang, Jiachen Chen, Ziyang Jin, Yongji Zhu, Xiujun Cai, Yifan Wang   +9 more
wiley   +1 more source

Effects of exercise with or without a hypocaloric diet on intermuscular and intramuscular fat: a systematic review. [PDF]

Aging Clin Exp Res
Prokopidis K, Varanoske AN, Veronese N, Kirk B, Triantafyllidis KK, Giannaki CD, Stavrinou PS, Church DD, Duque G.   +8 more
europepmc   +1 more source

Release strategy and egg parasitism of Telenomus podisi adults fed with different diets

Biological Control
The release of Telenomus podisi in the pupae stage for the control of Euschistus heros can be negatively affected by biotic and abiotic causes of mortality, reducing parasitoid emergence from pupae in the field.
Leonardo Roswadoski, Weidson P. Sutil, Gabriel S. Carneiro, Rodrigo M.A. Maciel, Aloisio Coelho Jr, Adeney F. Bueno   +5 more
doaj  

Chromosome‐Level Genome Assembly of the Leafcutter Bee Megachile rotundata Reveals Its Ecological Adaptation and Pollination Biology

Advanced Science, EarlyView.
The genome of Megachile rotundata, an extensively managed solitary pollination bee species, has been sequenced, covering 280.68 Mb and predicting 10 701 genes. The study reveals significant expansions of the Toll gene family and their abundant expression in diapause prepupae, highlighting enhanced immune responses during diapause. This genome serves as
Rangjun Shi, Pan Duan, Mengmeng Zhu, Rong Zhang, Zihua Zhao, Xin Nie, Hanhou He, Li Hou, Xianhui Wang   +8 more
wiley   +1 more source

Metabolic Features and Nutritional Interventions in Chronic Diseases. [PDF]

Nutrients
Luo Y, An P, Luo J.
europepmc   +1 more source

Effects of dietary basil (Ocimum basilicum) supplementation on reproductive hormones, semen parameters, and testicular development in Zandi male lambs

Veterinary and Animal Science
This study investigated the potential impact of feeding whole plant basil on sperm quality and the concentration of certain reproductive hormones in male lambs.
Golnor Kosari, Mohammad Ali Norouzian, Behzad Khorrami, Abouzar Najafi   +3 more
doaj  

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

Advanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao, Rui‐Ling Wang, Ran‐Xin Liu, Meng‐Ru Zheng, Li Zhao, Bao‐Feng Li, Jia‐Le Li, De‐Shen Liu, Xiao‐Xia He, Qin‐Bao Peng, Kai Li, Tian‐Xiao Lin, Ying‐Ying Liu, Sheng‐Ping He, Jun Lu, Shao‐Yi Zheng, Xiu Liu, Fang‐Ze Huang   +17 more
wiley   +1 more source

The Impact of Different Nutritional Approaches on Body Composition in People Living with Obesity. [PDF]

Curr Obes Rep
Galasso M, Verde L, Barrea L, Savastano S, Colao A, Frühbeck G, Muscogiuri G.   +6 more
europepmc   +1 more source