Results 41 to 50 of about 1,234,663 (267)
A 0.15-to-0.5 V Body-Driven Dynamic Comparator with Rail-to-Rail ICMR
Journal of Low Power Electronics and Applications, 2023 In this paper, a novel dynamic body-driven ultra-low voltage (ULV) comparator is presented. The proposed topology takes advantage of the back-gate configuration by driving the input transistors’ gates with a clocked positive feedback loop made of two AND
Riccardo Della Sala +4 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
The American Journal of the Medical Sciences, 1907 n ...
Gautier, A., Rico Oxley, A. J.
openaire +2 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Journal of Epidemiology and Community Health, 2006 Is exposure to antibodies and fatty acids in mother’s milk associated with development of autism? Autism is a disease of unknown aetiology, but complex pathogenesis that seems to have become more common in recent decades. We suggest that efforts exploring the aetiology of autism should pay special attention to patterns of breast and artificial feeding ...
M, Potts, B, Bellows
openaire +2 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
A RISC-V Fault-Tolerant Soft-Processor Based on Full/Partial Heterogeneous Dual-Core Protection
IEEE AccessThe low probability of single event upsets (SEU) within particular satellite orbits, makes Commercial-off-the-shelf (COTS) electronic components a viable solution for space system implementation, thanks to the introduction of design-level fault tolerance
Francesco Vigli +5 more
doaj +1 more source
FEBS Letters, EarlyView.Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source